Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage

This study is looking for adults aged 18 or over who are having surgery for certain types of bowel cancer. Specifically, it's for people having an operation on the left side of their colon or for a high rectal cancer, where the surgeon plans to join the bowel ends back together inside the tummy. You would need to be well enough for planned surgery and be part of the French social security system.

There are several reasons why you wouldn't be able to join. For example, if you need emergency surgery, or if your cancer requires a very extensive operation that removes a lot of the bowel. You also can't participate if you have a recurring cancer, or if you've had similar bowel surgery before. People with certain other medical conditions like inflammatory bowel disease, or a known allergy to the indocyanine dye, cannot take part.

Also, if you are pregnant, under guardianship, or if you simply prefer not to participate or cannot give informed consent, you won't be included. The study is designed for a specific group of patients to ensure the results are clear and helpful for future cancer treatment.

If you join this study, you'll be randomly put into one of two groups. One group will have the standard bowel cancer surgery, and the other group will have the same surgery but also receive the special indocyanine green dye injection during the operation to help the surgeons see blood flow. The dye is given once during the operation. After your surgery, the research team will keep track of your health for 90 days (about three months) to see if any complications, like an anastomotic leak, occur. Your regular follow-up appointments and check-ups during this time will be part of the study monitoring. There are no extra tests or medications beyond your normal care, except for the dye if you are in that particular group.