RecruitingNAINTERVENTIONAL

Respiratory Rehabilitation and Sleep Quality in COPD Patients

This study is for people with Chronic Obstructive Pulmonary Disease (COPD) who often struggle with sleep. COPD can cause breathing difficulties, cough, and phlegm. Many people with COPD also report poor sleep, which can make their breathing worse and affect their daily life. We know that respiratory rehabilitation, which involves special exercises and learning breathing techniques, can help with COPD symptoms and quality of life. However, we don't fully understand its effect on sleep. This study aims to find out if this rehabilitation program can improve sleep quality in people with COPD. Some people will do the program, and some won't, to see the difference.

At a glance

Status

Recruiting

Phase

Sponsor

University Hospital, Rouen

Enrolment target

Start

19 Feb 2025

Estimated completion

01 Feb 2028

COPD (Chronic Obstructive Pulmonary Disease)

What is this study about?

If you have Chronic Obstructive Pulmonary Disease (COPD), you'll know that it's a long-term lung condition that makes it hard to breathe. This happens because the air passages in your lungs become inflamed and blocked. Many people with COPD also experience problems with their sleep, which can make their breathing feel even worse during the day and affect their overall well-being. This study wants to explore a possible way to help.

We're focusing on something called respiratory rehabilitation. This is a special program that includes exercises and breathing techniques designed to help people with lung conditions manage their symptoms and improve their quality of life. While we know it helps with things like exercise ability and general health, we're not entirely sure how much it impacts sleep quality in people with COPD. That's what this study hopes to figure out.

We believe that taking part in a respiratory rehabilitation program could lead to better sleep for people with COPD. To test this idea, we'll compare two groups of people with COPD. One group will take part in the rehabilitation program, and the other group will continue with their usual care. By comparing these groups, we hope to see if the rehabilitation program truly makes a difference to how well people sleep.

Key takeaways

Study examines if breathing and exercise programs improve sleep in COPD.
People with COPD often have poor sleep, which can worsen breathing.
Respiratory rehabilitation is a proven treatment for COPD symptoms.
Participants will either do rehabilitation or continue usual care.
Sleep quality will be measured using overnight sleep tests.
The study aims to improve understanding of sleep in COPD.

Who may be eligible?

This study is looking for men and women aged 50 or older who have COPD. You should be in a stable condition, meaning you haven't had a flare-up of your COPD in the last month, and your doctor thinks respiratory rehabilitation would be good for you. You also shouldn't have taken part in a similar rehabilitation program in the past year.

There are also some reasons why you might not be able to join. For example, if you are very overweight (with a BMI of 30 or more), or if you already use a breathing machine for sleep problems like sleep apnea. We also can't include people who are taking certain medications that affect the brain, such as some strong pain relievers or sedatives, or those with other severe health issues like active cancer or certain types of nerve or muscle problems.

It's important that you can understand the study information and give your permission to take part. Women who could become pregnant must be using effective contraception. If you are pregnant or breastfeeding, you won't be able to join this study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 50 years old or older?
Do you have COPD and it's currently stable (no recent flare-ups)?
Have you NOT had a breathing exercise program in the last year?
Are you able to understand the study information and give consent?
Are you NOT very overweight (BMI under 30)?
Do you NOT use a breathing machine for sleep problems (like CPAP)?

Answer every question to see your result.

What does participation involve?

If you join this study, you will be placed into one of two groups by chance – like flipping a coin. One group will take part in a respiratory rehabilitation program, and the other group will continue with their usual care for about two months.

Before the study begins, and again after two months, you will have your sleep monitored overnight using a special test called polysomnography. This test involves wearing sensors that record your brain activity, breathing, and heart rate during sleep. This helps us understand your sleep patterns. There are no medications involved in this study, just the rehabilitation program for one group. The total duration of your active participation will be around two months.

Potential risks and benefits

Taking part in this study may offer potential benefits, especially for those in the rehabilitation group, as respiratory rehabilitation is known to improve breathing and quality of life for people with COPD. We hope it will also improve sleep. There are generally low risks associated with respiratory rehabilitation, but as with any exercise program, there's a small chance of discomfort or strain. The sleep monitoring tests are non-invasive and generally safe, though some people might find wearing the sensors a little uncomfortable. You are free to withdraw from the study at any time, for any reason, without it affecting your usual medical care.

Locations (4)

Chu Amiens
Verified postcode
Amiens, France· Not yet recruiting
Gh Le Havre
Verified postcode
Le Havre, France· Not yet recruiting
Centre de Sante Adir
Verified postcode
Rouen, France· Not yet recruiting
Chu Rouen
Verified postcode
Rouen, France· Recruiting

Common questions

What is respiratory rehabilitation?

It's a supervised program of exercises and breathing techniques designed to help people with lung conditions like COPD improve their fitness, strength, and breathing.

What is polysomnography?

It's a special sleep study where sensors are attached to you overnight to record your brain waves, breathing, heart rate, and other body functions to understand how you sleep.

Will I have to take any new medications?

No, this study does not involve taking or changing any medications. It focuses on the effects of a rehabilitation program.

How long will the study last for me?

Your active participation, including the rehabilitation program for one group and sleep tests, will last for about two months.

Can I leave the study if I change my mind?

Yes, you can leave the study at any time without having to give a reason, and it won't affect your medical care.

How to find out more

Marie-Anne Melone, MD, PhD

marieanne.melone@chu-rouen.fr (+33) 0232888265 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.