COPD : chronic obstructive Pulmonary disease research hub
16 indexed studies · 13 currently recruiting
- recruitingTherapeutic confirmatory (Phase III)
CORTICOP_Comparison of corticosteroids versus placebo on duration of ventilatory support during severe acute exacerbations of COPD patients in the intensive care unit: a multicentre randomized controlled trial
This clinical trial looks at whether a steroid injection called methylprednisolone helps people with severe COPD flare-ups in intensive care. Researchers want to see if this medicine helps patients breathe on their own sooner and spend less time on breathing machines compared to a dummy injection (placebo).
France - recruitingPHASE3
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
This study is looking at a new inhaler for people with COPD who are also at risk of heart and lung problems. It compares a new 'triple therapy' inhaler with an existing one to see if it improves health outcomes for these individuals.
United States · Argentina · Australia - recruiting
A Study to Understand the Accuracy of a New Breathing Device Compared to Standard Testing for Asthma and COPD
This study is testing a new, easy-to-use breathing device called the N-Tidal Handset. It hopes to improve how doctors diagnose asthma and COPD, making it quicker and simpler than current methods, especially in local clinics. It aims to see if AI can accurately read your breath to tell if you have asthma or COPD.
United Kingdom - active not recruitingNA
Effects of Vibrating Mesh Nebulisation in Patients With COPD During Non-invasive Ventilation (VMN-NIV)
This study compares two ways of giving breathing medicines – a newer vibrating mesh method and a traditional jet method – to people with COPD who use a breathing machine at home. We want to see which one works better for breathing and symptoms.
United Kingdom - not yet recruiting
Prevalence and Functional Impact of Urinary Incontinence in Women With Chronic Obstructive Pulmonary Disease Undergoing Rehabilitation: a Cross-sectional Study
This study looks at how common bladder leaks (urinary incontinence) are in women with long-term lung disease (COPD) who are in rehabilitation. It also explores how these leaks affect their daily lives and overall well-being.
France - recruitingNA
The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema
This study looks at a new way to treat severe emphysema called ETLA. It aims to see if this treatment is safe and effective by shrinking parts of the lung that are over-inflated, helping people breathe better and improve their quality of life.
Austria · Germany · Netherlands - recruitingNA
Routine vs On-demand ECMO for Lung Transplantation
This study looks at the best way to use a heart-lung support machine (ECMO) during lung transplants. We're comparing using it for everyone versus only using it if a patient needs it during the operation for conditions like severe lung disease.
Canada - recruiting
Assessing Functional Capacity in Directly and Remotely Monitored Home-based Settings: A Protocol for a Multinational Validation Study in Individuals With Chronic Respiratory Diseases
This study looks at a new step test for lung conditions like COPD. It checks if the step test is accurate, if it works well at home with remote support, and if it's safe. It compares the step test to other common exercise tests.
Canada · France - recruitingNA
Respiratory Rehabilitation and Sleep Quality in COPD Patients
This study looks at how a breathing and exercise program, called respiratory rehabilitation, might improve sleep in people with a lung condition called COPD. We want to see if better breathing exercises lead to better sleep quality.
France - recruiting
Using Multiomics to Define Mechanisms of Rhinovirus-induced Chronic Obstructive Pulmonary Disease Exacerbations to Develop Novel Therapies and Therapeutic Targets
This study investigates why common cold viruses worsen COPD, aiming to find new treatments. Researchers will compare people with COPD and healthy volunteers after giving them a safe, contained dose of the common cold virus. This will uncover how the body reacts and identify ways to tackle flare-ups.
United Kingdom - recruiting
Exploring How Viral Infections Affect People With Chronic Lung Disease
This study looks at how viruses cause flare-ups in people with long-term lung conditions like COPD and bronchiectasis. We need volunteers to provide samples when they are well and when they have a flare-up to understand the role of viruses and how the body's defence system reacts. This could lead to better treatments.
United Kingdom - recruitingNA
Balance Training Following Pulmonary Rehabilitation on Balance in People With Chronic Obstructive Pulmonary Disease (COPD)
This study is looking at a new balance training programme, called Sport4Steadiness, for people with COPD. It wants to see if the programme is helpful and easy to use, and if the study can be run smoothly. The aim is to help people with COPD improve their balance and potentially reduce falls.
United Kingdom - not yet recruitingPHASE1
Phase 1 PK Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD Patients
This study looks at a new inhaled medicine for people with COPD, called AERO-007. It's a combination of two drugs, given through a nebuliser. Researchers want to see how the body handles this new medicine, especially how much gets into the bloodstream compared to other similar treatments.
United Kingdom - active not recruitingNA
Changing Outcomes Through Achievement Emails in COPD Using Routine Healthcare Audits
This study looks at how emails sent to GP practices can help improve prescriptions for people with COPD. It tests if personalised emails or simple notification emails work better to help doctors follow national guidelines for lung medication.
United Kingdom - active not recruitingPHASE1
A Study to Investigate GB-0895 in Adults With Mild to Moderate Asthma or COPD
This study is looking into a new medication called GB-0895 for people with mild to moderate asthma or COPD. Researchers want to see if it's safe, how the body handles it, and if it works. It's an early-stage study to gather basic information.
United States · Germany · United Kingdom - not yet recruiting
Comparing Advanced Technologies to Standard Testing for the Diagnosis of Airway Disease in Hospital and Community Settings
This study compares new, easier breathing tests with standard methods to diagnose lung conditions like COPD. We want to see if these new tests are accurate, practical, and comfortable for patients, both in hospitals and local clinics, to help find problems earlier.
United Kingdom