A study in healthy people or otherwise healthy with overweight or obesity to compare 2 formulations of survodutide given in different ways, either as a pre-filled syringe or a pen-like injector
This Phase 1 study looks at an experimental medicine called survodutide, which is being developed to help treat obesity and related metabolic conditions. In this study, scientists want to compare how the body takes in the medicine when it is given using two different devices: a traditional pre-filled syringe versus an easy-to-use pen-like injector. The trial is open to adults aged 18 and older who are either at a standard weight or living with overweight or obesity, but otherwise in good health. Because this is an early-stage study, researchers are focusing on safety, how the body absorbs the medicine, and how comfortable each injection device is to use. Participants will receive close medical monitoring, regular health checks, and blood tests to track the medicine's journey through the body.
At a glance
What is this study about?
When a new medicine is developed, the way a person takes it is just as important as the medicine itself. Survodutide is an experimental treatment being researched to help people manage their weight and improve liver health. It is given as an injection under the skin. To make taking the treatment as simple and comfortable as possible, researchers are testing different ways to package and deliver it.
In this clinical trial, researchers are comparing two different delivery tools: a standard pre-filled syringe and an auto-injector pen. They want to check whether the body absorbs the medicine in the exact same way no matter which device is used. They will also look at how easy the devices are to use and whether either method causes mild skin irritation, such as redness or temporary soreness.
This is a Phase 1 clinical study. These early studies often involve healthy volunteers to help scientists see clearly how a drug behaves without interference from other illnesses or regular medicines. The results will help doctors choose the best injection device for larger trials and future patients.
Key takeaways
- Tests survodutide using two different injection devices: a pre-filled syringe and a pen injector.
- Open to adults aged 18 and older who are healthy or living with overweight/obesity.
- A Phase 1 trial designed to check safety, absorption, and device usability.
- Requires clinic visits, physical health checks, and routine blood tests.
- Taking part is completely voluntary and you can withdraw at any time.
Who may be eligible?
This trial is open to men and women aged 18 and over. You may be able to join if you are in good general health at a standard weight, or if you are living with overweight or obesity but have no other major health problems.
Being 'otherwise healthy' means you should not have significant long-term medical conditions, such as poorly controlled diabetes, severe heart trouble, or active liver disease. The medical team will review your health background and run basic tests to confirm you can safely take part.
You might not be eligible if you take certain regular prescription drugs, have allergies to similar injection medicines, or are pregnant or breastfeeding. A full medical check at the clinic will confirm whether the study is suitable for you.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- You are aged 18 or older.
- You are in good general health, with or without overweight or obesity.
- You do not have severe, uncontrolled chronic health conditions.
- You are comfortable receiving injections under the skin.
- You are able to travel to the trial clinic for appointments and tests.
- You are not currently taking part in another clinical drug trial.
What does participation involve?
Taking part begins with a screening appointment at the clinic. During this visit, staff will check your blood pressure, test your heart rhythm (using an ECG), and take blood and urine samples. If you are eligible, you will receive an injection of survodutide using either the syringe or the pen injector. Depending on the trial plan, you may receive one or more doses. You might be asked to stay at the clinic for a short period or attend several daytime follow-up visits. Doctors will take regular blood samples to measure drug levels and monitor your health closely until the medicine has fully left your system.
Potential risks and benefits
Locations (1)
- —UnverifiedGermany
Common questions
What is survodutide?
Survodutide is a new medicine being researched to help people manage excess weight and related metabolic health conditions.
Why compare two different injection devices?
Scientists want to ensure that a pen-style injector delivers the medicine just as reliably as a traditional syringe, while seeing if one is easier or more comfortable to use.
Will I be compensated for taking part?
Phase 1 trials often provide travel expenses and compensation for your time and inconvenience. The study team can give you specific details.
Is taking part safe?
All clinical trials follow strict UK safety regulations and ethics reviews. A medical team will monitor you closely during every stage of the study.
Can I leave the study if I change my mind?
Yes. Taking part is entirely your choice, and you can withdraw at any point without it affecting your standard medical care.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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