Healthy volunteer trial research hub
50 indexed studies · 0 currently recruiting
- ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test whether food influences the amount of BI 3731579 in the blood
This study is for healthy men to see if eating food changes how much of a new medicine, called BI 3731579, gets into their blood. It's an early-stage study to understand the medicine better.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test whether BI 1815368 influences the amount of metformin in the body
This study is looking for healthy men to understand how a new medicine, BI 1815368, affects how much metformin stays in the body. Metformin is a common treatment for diabetes. This early-stage research helps scientists learn more about new drugs safely.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A study to test how well different doses of BI 3810477 are tolerated by healthy men
This study is looking for healthy men aged 18 and over to test a new medicine called BI 3810477. It's the very first time this medicine will be given to people. The main aim is to see how well different doses are handled and if they cause any side effects.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test whether erythromycin influences the amount of BI 1291583 in the blood.
This study is looking for healthy people to help us understand how a common antibiotic, erythromycin, affects a new medicine called BI 1291583 in the body. It's a first step to see how these medicines might interact, making sure future treatments are safe and work well.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test how 2 different doses of BI 1291583 are taken up in the body when given in 3 different formulations.
This study is looking at a new medicine called BI 1291583. It wants to see how well different forms and doses of this medicine are absorbed by the body in healthy adults. It's a very early stage study to understand the medicine better.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
"A study in healthy people to test how 2 different formulations of a combination treatment (vicadrostat and empagliflozin) are taken up in the body and how food influences the amount of the medicines in the blood"
This study is looking at an experimental treatment that combines two medicines, vicadrostat and empagliflozin. We want to see how these medicines are absorbed and how food affects them in healthy volunteers, to help us understand how best to use them in the future.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to compare how 3 different formulations of survodutide are taken up in the body
This study is looking at how a new medicine, called survodutide, works in healthy people. We want to see how different forms of the medicine are absorbed by the body. This helps us learn more about how to give the medicine effectively.
Germany - ongoing, recruitingPhase I and Phase II (Integrated)- Other
Effect of itraconazole on the pharmacokinetics of a single oral dose of BI 1584862 in healthy male subjects (an open-label, two-period, fixed-sequence design study)
This study looks at how a common antifungal medicine, itraconazole, affects a new study drug called BI 1584862 in healthy men. It checks how much of the new drug gets into the body and how quickly, to understand how they work together.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test whether carbamazepine influences the amount of nerandomilast in the blood
This study is looking at how a new medicine, called nerandomilast, behaves in the bodies of healthy men when taken with carbamazepine, a common epilepsy drug. Researchers want to understand if carbamazepine changes how much nerandomilast is in the blood.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to compare how 2 different formulations of survodutide are taken up in the body
This study is looking at a new medicine called survodutide. We want to see how two different ways of giving this medicine are absorbed by healthy people. This helps us understand which way works best for the body.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test how bosentan influences the amount of nerandomilast in the blood
This study is looking at how a medicine called bosentan might change levels of another medicine, nerandomilast, in healthy men. It's a very early-stage trial designed to understand how the medicines interact in the body.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test whether carbamazepine influences the amount of BI 1810631 in the blood
This study is looking at how a common medicine, carbamazepine, affects a new drug called BI 1810631 in healthy men. Researchers want to see if carbamazepine changes the amount of BI 1810631 in the bloodstream, which is important for understanding how new medicines work together.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A study in healthy men to find out how different doses of BI 3009947 are tolerated and how different formulations or food influence how BI 3009947 is taken up into the blood
This study is for healthy men to test a new medicine called BI 3009947. We want to see how different doses affect the body and how it gets into the blood, especially when taken with food or in different forms.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test whether BI 3000202 affects how 2 other medicines (rosuvastatin and digoxin) are taken up in the body
This study is looking for healthy volunteers to see how a new medicine, BI 3000202, affects how your body uses two common medicines, rosuvastatin (for cholesterol) and digoxin (for heart conditions). It's an early-stage study to understand how medicines interact.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test whether BI 1291583 influences the amount of dabigatran in the body
This study is looking for healthy men aged 18 and over to see how a new medicine, BI 1291583, affects dabigatran. Dabigatran is a common blood-thinning drug. Scientists want to understand if taking both medicines changes the amount of dabigatran in the body.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test how itraconazole influences the amount of BI 764198 in the blood
This study is looking for healthy men to understand how a common anti-fungal medicine, itraconazole, affects levels of another trial medicine, BI 764198, in the body. It helps researchers learn how these medicines interact when taken together.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test how BI 1584862 is processed in the body
Scientists are doing a study to understand how a new medicine, called BI 1584862, moves through the bodies of healthy men. This helps them learn how the medicine works and if it's safe. It's the first step in testing new medicines.
Netherlands - authorisedHuman Pharmacology (Phase I)- Bioequivalence Study
A study in healthy people to compare two tablet formulations of pramipexole
This study is looking at two different tablet versions of a medicine called pramipexole to see if they work the same way in healthy people. It helps make sure new medicines are safe and effective before they are given to patients.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test how well different doses of BI 3000202 are tolerated and how they affect the way the body handles midazolam
This study is looking for healthy people to test a new medicine called BI 3000202. We want to see if it's safe, what dose people can take, and how it affects how your body handles another medicine called midazolam. It's an early-stage study.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A study to test how well different doses of BI 3034701 are tolerated by healthy men and people with overweight or obesity
This study is testing a new medicine, BI 3034701, for the first time in people. We want to see how different doses are handled by healthy men and people who are overweight or obese. It's about finding a safe dose.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men and women to test whether BI 1569912 influences the amount of repaglinide, midazolam and bupropion in the blood
This study is looking for healthy men and women to see how a new medicine, BI 1569912, affects other common medications like repaglinide, midazolam, and bupropion in the body. It helps us understand how different medicines might interact.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A study in healthy men to test how well different doses of BI 3731579 are tolerated
This study is looking for healthy men to test a new medicine called BI 3731579 for the first time. We want to see how different doses are handled by the body and if there are any side effects. It's an early step to make sure new medicines are safe.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test how itraconazole influences the amount of BI 3031185 in the blood
This study is looking for healthy men to understand how a common anti-fungal medicine, itraconazole, affects levels of a new medicine called BI 3031185 in the body. It helps check how they interact when taken together.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test how 3 different formulations of BI 764198 are taken up in the body and how this is influenced by food
This study is looking for healthy volunteers to test a new medicine called BI 764198. We want to see how your body absorbs it and if eating food changes this. It's an early-stage study to gather important information safely.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test how empagliflozin is taken up in the body when taken as a whole tablet or dissolved in water and mixed with food
This study looks at how a medicine called empagliflozin gets into the body. We want to see if it's absorbed differently when taken as a tablet or mixed with food after being dissolved. It's for healthy people.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test whether BI 764198 influences the amount of metformin in the body
This study is looking for healthy people to help us understand how a new medicine, BI 764198, interacts with metformin. Metformin is a common diabetes drug. We want to see if BI 764198 changes how much metformin stays in the body. It's an early-stage study to gather important safety information.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A randomised, single-blind, placebo-controlled trial to investigate safety, tolerability, and pharmacokinetics of single rising doses of BI 3000202 administered as tablet to healthy male subjects, and a randomised, open-label, single-dose, two-way cross-over relative bioavailability comparison of BI 3000202 as tablet with and without food in healthy male subjects
This early study looks at a new medicine, BI 3000202, in healthy men. It checks if the medicine is safe, how well the body handles it, and how it acts when taken with or without food. This is the first time it's being given to people.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test how BI 1810631 is taken up in the body when taken with or without food
This study is looking at how a new drug, BI 1810631, is absorbed by the body in healthy men. Researchers want to see if eating food at the same time makes a difference to how the drug works. It's an early stage study to understand the drug better.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test whether BI 1015550 influences the amount of nintedanib and pirfenidone in the blood
This study is looking for healthy men to find out how a new medicine, BI 1015550, affects how two existing medicines, nintedanib and pirfenidone, move through the body. It's a very early-stage trial to understand how these drugs interact.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test how BI 1291583 is taken up by the body
This study is looking for healthy men to test a new medicine called BI 1291583. It's an early-stage study to understand how the body uses this medicine and if it's safe. It's not for treating an illness.
Netherlands - authorisedHuman Pharmacology (Phase I)- Other
A study in healthy men to test how bosentan influences the amount of zongertinib in the blood
This study is looking at how two medicines, bosentan and zongertinib, interact in the body. Healthy men aged 18 and over are needed to see if bosentan changes the amount of zongertinib in their blood. This helps scientists understand how these medicines work together.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Relative bioavailability of two different formulations of nerandomilast and investigation of the food effect on new formulation following oral administration in healthy adult male and female subjects (an open-label, randomised, single-dose, three-way crossover trial)
This study looks at a new medicine called nerandomilast. We want to see how two different forms of this medicine are absorbed by the body. We'll also check if food changes how a new form of it works, helping us understand the best way to take it.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A study in healthy men to test how different doses of BI 3031185 are tolerated and how food influences the amount of BI 3031185 in the blood
This study is looking for healthy men aged 18 and over to test a new medicine, BI 3031185. We want to see how different doses are handled by the body and if food changes how much of the medicine gets into the blood. It’s a very early stage of testing.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men and women to test how BI 3000202 is taken up and processed by the body
This study is looking at a new medicine called BI 3000202 in healthy adults. Researchers want to understand how the body takes in, uses, and gets rid of this medicine. It's an early-stage study to check its safety and how it works in people.
Netherlands - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to test how well multiple doses of BI 765423 are tolerated by healthy men
This study is looking for healthy men aged 18 and over to test a new medicine called BI 765423. It's a very early-stage trial to see if the medicine is safe and how well people tolerate different doses. It's not for treating any illness.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to test how well different doses of BI 1584862 are tolerated by healthy men
This study is looking for healthy men to test a new medicine called BI 1584862. We want to find out if different doses are safe and how the body reacts to them. This is an early-stage study to learn more about the medicine before it's given to people with illnesses.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A study in healthy men to test how well different doses of BI 3802876 are tolerated
This study is looking for healthy men to test a new medicine called BI 3802876. It's the very first time this medicine will be given to people. Researchers want to see if it's safe and how different doses are handled by the body.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test how BI 1015550 is taken up in the body when given with or without food
This study is looking for healthy people to help us understand how a new medicine, called BI 1015550, is absorbed by the body. We want to see if eating food at the same time changes how the body takes up the medicine.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to compare two different tablets of BI 685509 and to test how food and esomeprazole influence the amount of BI 685509 in the blood
This study is for healthy volunteers to compare two versions of a new medicine, BI 685509. We want to see how the body handles it, especially with food or another common stomach medicine. It's a first step to understand this new treatment better.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to test whether multiple doses of BI 456906 have an effect on cardiac safety in people with overweight or obesity.
This study looks at a new medicine called BI 456906. We want to see if it's safe for people who are overweight or have obesity when given several times, especially checking its effects on the heart. It's an early-stage study with healthy people.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test whether esomeprazole influences the amount of BI 3000202 in the blood
This study is looking for healthy men aged 18 and over. It's testing how a new medicine, BI 3000202, acts in the body when taken with omeprazole, a common stomach medicine. This helps researchers understand how the medicines might work together.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A study in healthy people to see how zongertinib is taken up into the blood when given as tablets made by two different manufacturers
This study is looking at a new medicine called zongertinib in healthy volunteers. It wants to see how well two different versions of the tablet are absorbed into the body. This helps decide which version works best and is safest for future use.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to test how well healthy people tolerate spesolimab when given in 2 different ways.
This study is testing a new medicine called spesolimab in healthy volunteers. Researchers want to see how well people tolerate it when given in two different ways. It's a very early study to understand the medicine's safety before it's used for specific illnesses.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test how BI 1569912 is processed in the body
This study is for healthy men to understand how a new medicine, BI 1569912, works in the body. It's an early-stage study to see how the medicine is processed and leaves the body, helping researchers learn more about its effects.
Netherlands - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to test how BI 1839100 is taken up and handled by the body
This study is looking for healthy men to find out how a new medicine, called BI 1839100, works in the body and how it is removed. It's an early-stage study to understand the medicine better and make sure it's safe for people.
Netherlands - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy people to test how 2 different formulations of BI 690517 are taken up in the body and how probenecid influences the amount of BI 690517 in the blood
This study is looking at how two different ways of giving a medicine called BI 690517 are absorbed by the body in healthy people. Researchers also want to see if another medicine, probenecid, changes how much BI 690517 stays in the blood.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to test how different doses of BI 3731579 are tolerated by healthy people
This study is looking for healthy people to test a new medicine called BI 3731579. It's a very early stage trial to see how different doses are handled by the body and if there are any side effects. Your safety is the priority.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to test how well multiple doses of BI 3810477 are tolerated by healthy adults.
This study is looking for healthy adults to test a new medicine called BI 3810477. We want to see if it's safe and how well people tolerate different doses. It's an early-stage study to understand the medicine better.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy men to compare the amount of vicadrostat and empagliflozin in the blood when taken separately and together
This study is looking at how two medicines, vicadrostat and empagliflozin, behave in the body when healthy men take them. Researchers want to see if taking them together changes how much of each medicine is in the blood compared to taking them separately.
Germany - authorisedHuman Pharmacology (Phase I)- Other
A study in healthy people or otherwise healthy but overweight or obese to compare 2 formulations of survodutide given in different ways, either as a pre-filled syringe or a pen-like injector
This study is looking at how a new medicine, survodutide, works when given in two different ways: using a pre-filled syringe or a pen injector. It involves healthy adults, including those who are overweight, to see which way of giving the medicine is best.
Germany