A study in healthy people to test how vicadrostat affects the heart
This clinical trial is testing an experimental medicine called vicadrostat in healthy adult volunteers. Before any new medicine can be given to patients who are ill, scientists must check how safe it is and how it behaves in the human body. In this study, researchers are focusing specifically on the heart. They want to find out whether vicadrostat causes any changes to heart rate, blood pressure, or electrical heart rhythms. Because this is an early-stage study, participants will not receive any direct medical benefit from the medicine. To take part, you must be aged 18 or over and in good general health. Volunteers will be looked after by a specialist medical team and will have regular heart tracings and blood tests. Taking part is completely voluntary, and you can leave at any time.
At a glance
What is this study about?
When scientists develop a new medicine, their first priority is to make sure it is safe to use. This clinical trial is studying an experimental medicine called vicadrostat. Doctors want to understand how the medicine moves through the body and, in particular, whether it has any effect on the heart.
The heart relies on steady electrical signals to pump blood properly. Sometimes, medicines can cause minor, temporary changes to these signals or alter the heart rate. By testing vicadrostat in healthy volunteers, doctors can track these signals very carefully using standard heart tests, such as electrocardiograms (ECGs).
This is a Phase 1 trial, which is one of the earliest stages of human research. Because the volunteers are already healthy, the goal is not to cure an illness. Instead, the study aims to gather clear safety information. If the results show that vicadrostat is safe for the heart, researchers can take the next steps toward testing it in patients who might benefit from it in the future.
Key takeaways
- This is an early-stage study testing the safety of a medicine called vicadrostat.
- The main goal is to check how the medicine affects the heart and heart rhythms.
- The trial is open to healthy adults aged 18 and older.
- Participants will have regular health checks, including blood tests and heart tracings (ECGs).
- Taking part is completely voluntary, and you can withdraw at any time.
Who may be eligible?
This trial is open to adults aged 18 and over who are in good general health. Men and women can both apply to take part.
Because the study is designed to test safety in healthy people, you will generally not be able to join if you have serious long-term medical conditions, particularly heart disease, high blood pressure, or kidney problems.
Before you can join, the study team will carry out health checks to make sure taking part is safe for you. They will check your medical history, test your heart rhythm, and review any regular medications or supplements you take.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- You are aged 18 or older.
- You are in good general health.
- You do not have a history of heart conditions.
- You are able to travel to the clinic for scheduled visits or monitoring.
- You are happy to have routine health tests like blood draws and ECGs.
What does participation involve?
Taking part involves attending a specialist clinical research clinic. First, you will have a screening visit to check your general health, blood results, and heart rhythm. If you are suitable and decide to take part, you will be given the study medicine, vicadrostat. You will spend time at the clinic where doctors and nurses can monitor you closely. They will take regular blood samples, check your blood pressure, and perform ECG heart tests to see how your body responds. After the treatment period, you will have a final follow-up visit to ensure you are well. The study team will explain the exact number of clinic visits and hours required before you agree to join.
Potential risks and benefits
Locations (1)
- —UnverifiedGermany
Common questions
What is the main purpose of this study?
The study aims to find out if the medicine vicadrostat causes any changes to heart function or heart rhythms in healthy adults.
Will I be paid for taking part?
Healthy volunteer trials usually offer payment to cover your time and travel expenses. The study team can give you details about this.
Do I have to stay overnight at the clinic?
Early-stage trials often involve a short stay or full-day visits so doctors can monitor you closely. The study team will explain the schedule before you sign up.
What happens if I feel unwell during the trial?
Doctors and nurses will be on hand throughout the study to care for you and treat any side effects straight away.
Can I leave the study if I change my mind?
Yes. You can leave the trial at any point, and you do not need to give a reason.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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