A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Laroprovstat, Rosuvastatin and Placebo on LDL-C in LLT-naïve Patients.

To be considered for this study, you need to be at least 18 years old. We're looking for people who have high cholesterol but have never taken cholesterol-lowering medication before in the last three months. It's also important that you don't have a history of heart disease or blocked arteries, and your risk of developing these over the next 10 years is considered low.

There are certain reasons why you wouldn't be able to join. For example, if you've had problems taking statin medicines in the past, or if you have certain other health conditions that aren't well-controlled. These include severe high blood pressure, type 2 diabetes, or an underactive thyroid. The study also cannot include people of Asian origin.

If you decide to take part in this study, you will be assigned to one of several groups by chance. You might receive the new combination medicine, one of the medicines by itself, or a dummy pill (placebo). You won't know which one you're taking, nor will your study doctor, to ensure the results are fair.

You'll need to attend regular visits to the clinic for check-ups. During these visits, doctors and nurses will monitor your health, take blood samples to check your cholesterol levels, and ask you about any side effects you might be experiencing. They will also make sure you're taking the study medicine as prescribed. The total length of your participation in the study will be explained to you by the study team, including how long you'll be taking the medication and how many follow-up visits you'll need.