EPA for Metastasis Trial 2

To join this study, you need to be an adult (18 years or older) and have received a diagnosis of bowel cancer that has spread to your liver. You must be planning to have surgery to remove these liver growths with the aim of curing the cancer. If you've had previous liver surgery for the current spread, you unfortunately can't join, but if this is a new spread needing surgery, you might be eligible.

You also can't join if you have cancer that has spread to other parts of your body that can't be treated, or if you're already regularly taking other omega-3 supplements or fish oil. People with certain allergies (like fish, soya, peanuts) or conditions (like certain bleeding disorders) are also not able to take part. Women who are pregnant or breastfeeding, or who could become pregnant and are not willing to use effective contraception, also cannot join.

It's important that you're able to follow the study's instructions and attend all follow-up appointments. If you've had other cancers in the last 5 years (apart from bowel cancer or very early-stage cancers like non-melanoma skin cancer that was completely removed), you also won't be able to participate.

If you join the study, you'll be given either the EPA supplement or a dummy capsule to take. You'll start taking these capsules before your planned liver surgery and continue for up to four years after your surgery. You'll have regular hospital visits and check-ups, just as you would normally for your cancer care, but there may be some additional assessments or questionnaires related to the study. The study doctors will monitor your health and any cancer recurrence carefully throughout this period.