Active not recruitingOBSERVATIONAL

Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction

This study is for people who have recently had a heart attack. Doctors want to understand why some patients go on to develop further heart problems, especially a condition called 'diastolic heart failure' where the heart struggles to relax properly. Researchers will check how stiff blood vessels are, along with other health factors, about one month after the heart attack. The main goal is to find out which signs and tests can help predict who might be at higher risk of developing future heart issues, another heart attack, or bleeding problems. This information could lead to better ways to identify and care for patients after a heart attack, helping them live healthier lives.

At a glance

Status

Active not recruiting

Sponsor

University Hospital, Lille

Enrolment target

2,000

Start

17 Feb 2020

Estimated completion

01 Mar 2030

Myocardial Infarction Vascular Stiffness Heart Failure

What is this study about?

This research study is looking at people who have recently experienced a heart attack. After a heart attack, it's really important for doctors to understand which patients might be at higher risk of developing other serious health problems, especially new heart conditions or a recurrence of a heart attack.

One particular area of interest for this study is a condition called 'diastolic heart failure'. This is when the heart muscle becomes stiff and struggles to relax properly between beats, making it harder to fill with blood. The study aims to deeply investigate various factors, including how stiff a person's blood vessels are (this is called 'vascular stiffness'), about a month after their heart attack. They will also look at other things like imaging results and general health information.

The main goal is to identify specific things – whether they are signs doctors can see, measurements from tests, or results from scans – that are linked to a poorer outlook for patients. This includes figuring out who might be more likely to develop diastolic heart failure, have another heart attack, or experience bleeding complications. By understanding these risk factors better, doctors hope to improve care and tailor treatments more effectively for patients after a heart attack.

Key takeaways

This study focuses on people who have recently had a heart attack.
It aims to find new ways to predict future heart problems like heart failure.
Researchers will assess blood vessel stiffness and other health factors.
No new medications are given as part of this study.
Participation involves assessments typically around one month after your heart attack.

Who may be eligible?

To be part of this study, you need to be at least 18 years old and have had a heart attack within the last 48 hours. You also need to agree to take part by signing a consent form and be covered by national health insurance in France.

There are some reasons why you couldn't join. For example, if your heart attack was caused by something other than a blocked artery (called a 'Type 2 MI'), or if more than 48 hours have passed since your heart attack symptoms started. We also can't include people who are pregnant, breastfeeding, or if you simply don't wish to take part. Also, if you don't have French national health insurance, you wouldn't be able to join this particular study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

I am at least 18 years old.
I had a heart attack within the last 48 hours.
My heart attack was not a 'Type 2 MI' (caused by something other than a blocked artery).
I am not pregnant or breastfeeding.
I would be willing to sign a consent form to participate.

Answer every question to see your result.

What does participation involve?

If you decide to join this study, you would mostly be involved in assessments around one month after your heart attack. This would include various checks and scans to measure things like the stiffness of your blood vessels and how well your heart is working. These are all standard medical evaluations. The study will mainly involve collecting information and results from these assessments at that one-month point. You won't be given any new medications specifically for the study. The total duration of your active participation would likely be focused around that one-month assessment period, though researchers may follow your health records over time.

Potential risks and benefits

Taking part in this study may not offer immediate personal health benefits, but the information gained could greatly help improve care for future heart attack patients. All assessments are standard medical procedures, so any risks are generally those associated with routine hospital visits and tests. You are free to withdraw from the study at any time without giving a reason, and this will not affect your medical care.

Locations (1)

Institut Coeur-Poumon, CHU
Verified postcode
Lille, France

Common questions

What is 'vascular stiffness'?

Vascular stiffness means how flexible your blood vessels are. Stiffer vessels can sometimes indicate a higher risk of heart problems.

What is 'diastolic heart failure'?

This is a type of heart failure where your heart muscle struggles to relax properly between beats, making it harder to fill with blood.

Will I be given new medicine if I join?

No, this study doesn't involve giving you any new medicines. It focuses on gathering information from existing assessments.

How long will I be involved in the study?

Your active participation will mainly be focused on assessments around one month after your heart attack.

Will my regular doctors still look after me?

Absolutely, your usual medical care and treatment will continue as normal during and after the study.