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Data Clustering Study With Artificial Intelligence and Phenotyping of Patients With Acute Pulmonary Embolism

This research is looking at people who have had a lung blood clot, called a pulmonary embolism. We're using special computer programs, a bit like artificial intelligence, to look at lots of patient information and group them together. The goal is to see if certain groups of patients have similar experiences and outcomes after their diagnosis, such as whether their clot comes back or if they develop ongoing problems. By understanding these patterns over six months, especially during their first three months of treatment, doctors hope to make more informed decisions about care for future patients. This study will look at past patient records and also include new patients over the next couple of years. Your current medical care will not be affected by this research.

At a glance

Status
Recruiting
Sponsor
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Enrolment target
2,500
Start
11 Dec 2023
Estimated completion
01 Jul 2026

What is this study about?

This study is about understanding lung blood clots, also known as pulmonary embolisms. When someone has a pulmonary embolism, a blood clot blocks a blood vessel in their lungs, which can be very serious. Doctors want to learn more about why some people recover well and others might have ongoing issues or even another clot.

To do this, researchers are using a type of computer science called Artificial Intelligence (AI). Don't worry, this doesn't mean robots are treating patients! It means computers are being used to sort through lots of medical information from many patients. The computer programs look for hidden patterns and similarities to group patients into 'clusters' or groups. The idea is that patients in the same group might have similar health experiences.

The study will look at patient information collected over six months after their diagnosis, including details about their first three months of treatment. By studying these groups, doctors hope to find early clues that could help predict how individual patients might fare. For example, they want to see if specific patient groups are more likely to have another blood clot or develop a condition called chronic thromboembolic pulmonary hypertension (CTPE) which causes ongoing breathing problems. The findings from this research could help doctors make more personalised and effective decisions for patients with pulmonary embolism in the future.

Key takeaways

  • This study uses computer analysis to group patients with lung blood clots.
  • It aims to better understand how pulmonary embolism affects different people.
  • No extra tests or appointments are needed if you participate.
  • Your current medical treatment will stay exactly the same.
  • The research helps doctors make better decisions for future patients.
  • You can choose not to participate without affecting your care.

Who may be eligible?

To be part of this research, you need to be at least 18 years old. You must also have been diagnosed with an acute pulmonary embolism, meaning a new and sudden lung blood clot, at CHITS hospital. This applies whether you were admitted to the hospital or seen as an outpatient for your condition.

There are a couple of reasons why someone might not be able to join. If your pulmonary embolism only involved very small blood vessels (called sub-segmental pulmonary embolisms), you wouldn't be included. Also, if you don't wish to take part, that's perfectly fine, and you won't be included.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. I am 18 years old or older.
  2. I have been diagnosed with a new pulmonary embolism at CHITS hospital.
  3. My pulmonary embolism was not just in very small blood vessels (sub-segmental).
  4. I am happy for my existing medical data to be used for research.
Answer every question to see your result.

What does participation involve?

If you are included in this study, you won't need to do anything extra. This research uses information that is already being collected during your regular medical appointments and check-ups for your pulmonary embolism. This means there are no additional visits, tests, or procedures specifically for this study.

The research team will simply gather the information from your consultations and various check-ups that happen as part of your standard care over six months after your diagnosis. This will help them understand your condition and recovery journey. Your participation will not change your current medical care in any way.

Potential risks and benefits

There are no direct risks to taking part in this study because it only involves looking at information already collected from your routine medical care. Your current treatment and care will not be affected. There are also no direct personal benefits for you as an individual; however, your anonymous data will contribute valuable information that could help doctors better understand and treat future patients with pulmonary embolism. You have the right to decide not to take part at any point, and this decision will not impact your medical care.

Locations (1)

  • centre hospitalier intercommunal Toulon La Seyne sur Mer - Internal and vascular medicine
    Verified postcode
    Toulon, France· Recruiting

Common questions

What is a pulmonary embolism?

A pulmonary embolism is a serious medical condition where a blood clot travels to the lungs and blocks a blood vessel, affecting breathing and heart function.

What is 'Artificial Intelligence' in this study?

Here, AI means using smart computer programs to look at lots of patient data and find hidden patterns or groups, helping us understand the illness better.

Will my treatment change if I'm in the study?

No, your medical care and treatment will not change. This study only uses information already collected during your standard care.

How long will my information be used?

Information from your medical records will be collected for six months after your pulmonary embolism diagnosis for the purposes of this study.

Can I say no to being in the study?

Yes, absolutely. If you prefer not to have your information included, you can decline, and it will not affect your medical care.

How to find out more

Jean-Philippe Suppini

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Data Clustering Study With Artificial Intelligence and Pheno…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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