- authorisedTherapeutic use (Phase IV)
Reduced-dose versus full-dose systemic thrombolysis for high-risk pulmonary embolism: a multicentre, randomised, open-label, blinded-endpoint trial
This hospital study compares a reduced dose of a clot-busting drug against the standard full dose for severe blood clots in the lungs. Researchers want to see if the lower dose clears the clot just as well, while lowering the risk of dangerous bleeding complications for patients.
Denmark · Sweden · Norway - recruitingTherapeutic use (Phase IV)
Randomized clinical trial comparing the diagnostic quality and diagnostic accuracy of pulmonary CT angiography performed with spectral CT among three iodinated contrast administration protocols, with 20, 30 and 40 mL
This study looks at different ways to do a special type of X-ray scan called a CT pulmonary angiogram. We want to see which method best finds blood clots in the lungs (pulmonary embolism) using less dye, making the scan safer and clearer for patients.
Spain - active not recruitingPHASE4
Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism
This study looks at treating blood clots in the lungs (pulmonary embolism). It compares standard blood thinners with a new treatment using blood thinners and a device that helps dissolve clots faster, to see which is safer and more effective.
United States · Austria · France - recruitingPHASE3
RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
This study compares two medicines, rivaroxaban and LMWH, for preventing blood clots in people with leg injuries needing a cast or brace. It aims to see if rivaroxaban is as good as, and easier to use than, LMWH for those at higher risk of clots.
France - recruitingNA
GEKO Venous Thromboembolism Prevention Study
This study compares two ways to prevent blood clots (VTE) in stroke patients who can't move much. It looks at the standard treatment (IPC) versus a new device called geko™ to see which works better over three months.
United Kingdom - recruitingPHASE4
Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism
This study looks at the best way to treat small blood clots in the lungs (isolated subsegmental pulmonary embolism) in people at low risk. It compares watching carefully without treatment to giving blood-thinning medicine to reduce bleeding risks.
Belgium · Canada · France - recruitingNA
The PERSEVERE Study
The PERSEVERE Study is looking at a new device, the FlowTriever System, to treat severe lung blood clots (pulmonary embolism). It compares this new approach to standard NHS care for people with high-risk clots, aiming to see which is more effective.
United States · France · Germany - recruiting
Data Clustering Study With Artificial Intelligence and Phenotyping of Patients With Acute Pulmonary Embolism
This study uses computers to group people with lung blood clots (pulmonary embolism) to understand their condition better. It aims to find patterns in their health and recovery over six months to help doctors make better treatment choices in the future.
France - recruitingNA
Is Clonal Hematopoiesis of Indeterminate Potential Associated With Unprovoked Pulmonary Embolism?
This study looks at a condition called 'clonal hematopoiesis of indeterminate potential' (CHIP) and whether it might be linked to unexplained blood clots in the lungs (pulmonary embolism). Researchers want to see if CHIP is common in these cases and plays a role in why they happen.
France - authorisedTherapeutic use (Phase IV)
PERCUTANEOUS EMBOLECTOMY, LOW DOSE THROMBOLYSIS OR HEPARIN FOR INTERMEDIATE HIGH RISK PULMONARY EMBOLISM
This study is looking at different ways to treat 'intermediate-high risk' pulmonary embolism (PE), which is a blood clot in the lungs. It compares dissolving the clot with medicine or removing it with a small procedure, to standard blood thinners. The goal is to find the best way to help people get better.
Denmark - recruiting
Post-Market Celect Platinum Vena Cava Filter and Gunther Tulip Retrieval Set Study
This study looks at how well a device called a Celect Platinum Vena Cava Filter works over time. This filter helps stop blood clots from reaching your lungs. Researchers want to make sure it's safe and effective for patients with blood clot issues.
United States · Spain · United Kingdom - active not recruiting
Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales
This study looks at the health of people in England and Wales one year after they left intensive care for COVID-19. Researchers will compare their health to people who were in intensive care for other reasons. The aim is to understand long-term health effects.
United Kingdom - recruiting
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
This study looks at how well a device called the Indigo Aspiration System works long-term for clearing blood clots in the lungs (pulmonary embolism). It also checks its safety and how it affects patients' health over time.
United States · Australia · Austria - authorisedPhase I and Phase II (Integrated)- Other
Ventilation/Perfusion PET/CT with Galligas and 68Ga-MAA for regional lung function assessment after pulmonary embolism
This study is looking at a new way to scan lungs called V/Q PET/CT. It uses special gases to help doctors see how well blood flows and air moves in the lungs after a pulmonary embolism. The goal is to better understand how these clots affect lung function.
France - recruiting
Inari VISION Registry
This study looks at how Inari Medical devices work for people with blood clots in their lungs (pulmonary embolism). It's for adults treated with these devices to see how they recover and if the devices are safe and effective in real-world use.
Italy · Portugal · United Kingdom