RecruitingOBSERVATIONAL

CoMbination of Data From European Cohorts as Part of the European MORPHEUS Project [HORIZON-HLTH-2022-11-01] - "MC-MORPHEUS".

This project, called MC-MORPHEUS, is part of a larger European effort to understand and treat a condition called Venous Thromboembolism (VTE). VTE happens when blood clots form in veins, often in the legs or lungs. Researchers are gathering health information from thousands of patients across eight European countries into one big database. The goal is to find clues in this information – things like medical history, blood test results, and body scans – that can help doctors predict who might have recurring clots, bleeding problems, or other serious issues. They also want to understand what influences treatment decisions. Ultimately, this research aims to develop a tool to help doctors make better, more personalised choices about how long and with what medicines to treat VTE, to keep patients as healthy as possible in the long term.

At a glance

Status

Recruiting

Sponsor

University Hospital, Brest

Enrolment target

20,000

Start

01 May 2024

Estimated completion

30 Dec 2029

Venous Thromboembolism

What is this study about?

Imagine you or someone you know has had a blood clot, a condition doctors call Venous Thromboembolism (VTE). Sometimes these clots cause problems again, or the medicines to treat them can cause side effects like bleeding. This research project, called MC-MORPHEUS, is trying to find better ways to help people with VTE, especially those whose clots happened without a clear reason.

The main idea is to collect and combine lots of health information from thousands of patients who have already been part of studies in different European countries. This information includes things like their medical history, results from blood tests, and details from scans they've had. By putting all this data together in one huge database, scientists hope to spot patterns and discover new markers – think of them as clues – that can help predict a patient's risk of future blood clots, bleeding problems, or other serious health issues down the line.

Ultimately, the team wants to create a smart tool that doctors can use. This tool would take into account a patient's unique health information to help decide the best long-term treatment plan for them. It's all about making sure each patient gets the most effective and safest care possible, improving their lives after a VTE diagnosis.

Key takeaways

This study focuses on improving care for people with blood clots (VTE).
It combines existing health information from thousands of patients across Europe.
The aim is to find clues (biomarkers) to predict future risks like more clots or bleeding.
Researchers hope to develop a tool to help doctors make better treatment decisions.
No new patients are being recruited; it uses anonymised data from past studies.
The ultimate goal is to offer more personalised and effective long-term VTE treatment.

Who may be eligible?

This study isn't looking for new patients to join right now. Instead, it's collecting information from existing medical studies (called 'cohorts') that are already running in Europe.

To be included, the original study must be part of the larger MORPHEUS project team. Also, the patients in those original studies must have given their permission (consent) for their health information to be used for research like this.

In short, if your health information is already part of a study that is connected to the European MORPHEUS project, and you agreed for your data to be used, then your anonymised information might contribute to this research. You wouldn't be asked to do anything new for this particular project.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

My health information is from a study that is part of the MORPHEUS project team.
I previously gave permission (consent) for my data to be used in research.
My data is about Venous Thromboembolism (VTE) or related health conditions.
I am not directly involved as a new patient in this specific study.

Answer every question to see your result.

What does participation involve?

If you are part of an existing study that contributes data to MC-MORPHEUS, your participation doesn't involve any new visits, tests, or medication. This project uses anonymised health information that has already been collected from you in those previous studies. Your personal identity will not be shared. You wouldn't be asked to do anything extra, nor would you receive any direct communication from this particular study.

Potential risks and benefits

There are no direct risks or benefits to individuals whose historical data is used in this study, as it involves analysing anonymised existing information, not direct patient involvement. You would not be identified, removing privacy risks related to your personal details. The potential benefit is to future patients with VTE, as the findings could lead to better tools for doctors to predict risks and guide treatment, ultimately improving long-term care for many. In the original studies where your data was collected, you always had the right to withdraw your consent to participate, which would also apply to the use of your data in analyses coordinated by the MORPHEUS project.

Locations (1)

Chu Brest
Verified postcode
Brest, France· Recruiting

Common questions

What is Venous Thromboembolism (VTE)?

VTE is a medical condition where blood clots form in your veins, often in the legs (Deep Vein Thrombosis or DVT) or lungs (Pulmonary Embolism or PE).

Is this study looking for new volunteers?

No, this study is collecting and combining information from patients who have already been part of other health studies in Europe. It's not recruiting new individual participants.

Will my personal details be shared?

No, your personal details will not be shared. The study uses 'anonymised' data, meaning any information that could identify you has been removed.

What is the main goal of this research?

The goal is to find better ways to predict who is at risk of future VTE problems and to help doctors decide the best long-term treatment for individual patients.

Which countries are involved in this project?

Researchers from France, the Netherlands, Spain, Germany, Switzerland, Poland, Sweden, and Denmark are working together on this project.

How to find out more

Francis COUTURAUD

francis.couturaud@chu-brest.fr 298347348 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.