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Allopurinol seems to be making my Gout worse

Posted , 8 users are following.

mark38479
mark38479

Hi I started Allopuirnol a few weeks back after suffering years of painful Gout. Unfortunatley I seem to be getting worse rather than better.

I started on 100mg then to 300 and still suffering. Seems to me that the more i take the worse it is getting.

If anyone else has suffered taking Allopurinol please let me know

Many Thanks Mark

0 likes, 20 replies

20 Replies

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  • rick03247
    rick03247 mark38479

    Posted

    Hi mark, had same problem myself on Allopurinol, firstly it triggered attack after attack and then i started to have chronic pain in my joints with real stiffness as well. Doc said it was one of the rare side affects so i came off Allopurinol and went on Adenuric, with pretty much the same effects. Joint stiffness and pains in the kidney area. Went back to doc and he says theres nothing else on the market, but carry on with Adenuric. Had blood tests again since on this tablet and waiting for results. Also when i was on Allopurinol i would have gout in my knee then in the morning it would be in my foot as well as my knee and my leg would be bright red from the knee down to the foot which really concerned me, and the pain was like never before, with a really bad fever, absolutely unbearable. I have had a prolapsed disc twice now and i would compare the intensity of pain for gout and a prolapse disc the same. A acute attack or flare up is so painful that nobody understands what you go through, i am literally on 2 crutches and cannot be mobile at all.   
    • jeff5518
      jeff5518 rick03247

      Posted

      Uloric is another drug. And it's better on your kidneys.

    • rustygecko
      rustygecko rick03247

      Posted

      Your doctor is wrong. It is not a rare side effect. It is 100% normal. ANY reduction therapy WILL trigger gout, unitl the stores of monosodium urate in the tissues are eliminated. 

      If you are getting pain in your kidneys you should seek attention about that.

      You should have been prescribed colchecine or similar when you were given the allopurinol. 

      I would definately suggest you change your GP to one who pays more attention to the material sent to him by NICE.

  • rustygecko
    rustygecko mark38479

    Posted

    Allopurinol will make gout worse for several months, and your doctor should have:

    a) warned you of this;

    b) given you something like colchecine to take as profilaxis. 

    The fact that you are getting these attacks shows that it is working and that you need the allopurinol. 

    The reason is that the allorpinol will be uncovering stores of monosodium urate crystals in your soft tissues that have been groing for perhaps a decade. As these stores are released it causes gout. Not taking the allopurinol or another form of uric acid reduction will lead to complications, most notably heart disease, stroke and kidney disease. 

    The other thing you should do with allopurinol is increase the amount of water you drink to flush out the excess uncovered urates, and to protect your kidneys. 

     

  • Guest
    Guest mark38479

    Posted

    It's not t5hat simple. I take Allupirinol and it works b rilliantly for me, albeit I am not totally pain free. If you forget to take it, or you increase the dosage, you will suffer temprarely. Colchesine will help, but like you I can't take it because of the effect it has on me. 

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