I'm so glad I found this post. I'm currently on day 10 of a 10 day treatment of Clarithromycin 500mg/twice daily, one more pill to go tonight. The treatment is for a chest and skin infection that have been resistant to other antibiotics so far. Due to other complications, my body is quite run down right now and not fighting off infection well at all. I do struggle with anxiety and bipolar disorder, but do not take medication for either, and generally am able to maintain a functioning life and schedule, and I manage alright. 16 years of a mood disorder, several panic attacks, daily anxiety, and I've never felt this bad that I can remember.
The first couple days of treatment I was lethargic and nauseous, but that passed. Then I had a few days that I felt pretty alright, as close to normal as I could be, I think. I did start experiencing some weakness in my legs, heart palpitations, and shortness of breath, digestive discomfort, but that wasn't brand new to me, as the past few weeks have already included those symptoms, due to another health issue, so I chalked it up to that, even though those symptoms had not been present for maybe a week or so before starting the Clarithromycin.
Then, within the past few days, I suddenly started experiencing extreme depression and anxiety, uneasiness, nothing like what I deal with on a regular basis. Uncontrollable sobbing, for hours a day, a constant feeling of fear and just "wrongness", zero motivation, loss of interest in most things I used to take pleasure from, have been stuck in bed for days, extremely negative thoughts (very non-typical for me), loneliness, agitation, nothing brings any sense of comfort or relief, other than sleep, which I'm not getting a lot of.
I only have one tablet left, I'm undecided about whether or not to finish the course. On one hand, one more tablet can't make things much worse, and I'm still extremely anxious about the infection, as it doesn't appear to be completely cleared up even after completing most of the course. But, on the other hand, if the infection isn't going to improve with just one more, maybe it'd be best to start the process of flushing it out of my system.
Anyway, the negative thoughts were starting to erode pretty deeply, so reading all these stories has given me a glimmer of hope. I will do my best to hang on to some positivity over the next few days, and have faith that this storm will pass!
Thank you to everyone who's contributed here, knowing there's a light at the end of the tunnel is all I need to push past this!