Anyone has completely recovered from the effects of Amlodipine?

Posted , 6 users are following.

Hello dear forum members ...

I have been on this forum for months but could not be sure if anyone has fully been off amlodipine and reversed all the side effects?

It appears that there are many stories of relief .. but always some issues linger .. and it may or may not be because of subsequent changer of medicine for hypertension .. or some other medical or age related issues having subsequent effects ...

I am really curious if anyone has fully recovered .. Might i invite anyone who wish to share .. i relate myself in this description :

Male 50 ... 3.5yrs on / 5 mths off .. amlodipine 5mg to nebivolol 5mg... residual issues .. neck and shoulder tension .. tiredness .. lack of mood .. mild to moderate.

Anyone care to elaborate their......?

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  • Posted

    I think you have another post asking how long it takes to recover completely - which interests me too.  There are lots of replies which are unclear.  I am not strongly persuaded by posts to the effect that "I got this side effect from taking the drug and still have it months after stopping".

    I should know more next week when I have a DATscan.  I was diagnosed with Parkinsons disease by a neurologist in France on 15 March 2018, but it is suspect, which is why he referred me for a DATscan.  My only real symptom is tremor (and associated phenomena like "cog-wheel" joint movement, or muscle stiffness).  Parkinsons disease is possible (the best fit) but odd with just one symptom.  The neurologist claimed I had a "Parkinsons mask" - no movement in the lower face, but its not obvious to me, my family or my GP.  No shuffling, balance issues, non motor issues, small handwriting, slow movement etc.  The DATscan should shine a lot of light. 

    But I stopped taking Amlodipine on 17 March, and whilst I thought I experienced a 2 week "detox" (lots of aches and shivers on various days) the tremor symptoms havent gone (maybe they are a bit less but its very subjective). Today is 10 May 2018.

    I am 57 years old, and first demonstrated the tremor to my wife while skiing in late January.  I first remember mentioning it around Christmas.  She thinks she noticed it early December after visiting her father (who has a tremor).  I started taking Amlodipine on 24 November 2017.  It is suspicious.

    There are 2 proper medical reports of DIP (Drug induced Parkinsonism) that I can find (there are lots of blog claims but muddled).  The first proper case recovered after "about a month" after stopping the drug.  The 2nd recovered after "several months" after stopping the drug

    In medical papers about DIP, it IS associated with Calcium Channel Blockers - but Amlodipine is never cited.  The papers note that symptoms can persist up to 6 months after stopping, commonly, but up to 2 years later in some cases.

    Some DIP never recovers even after the drug is stopped, although it is likely this is almost always the drug uncovering an idiopathic sub-clinical Parkinsons disease (you had it anyway - the drug revealed it)

    The drug itself has a chemical half-life of 30-50 hours - so chemically it takes 7 - 11 days to be completely out of the system.  But it is possible that it affects parts of the body whilst in the system, and those parts take longer than 7-11 days to recover (like up to 6 months). 

    So, I am interested to hear from anyone with side effects, particularly tremor or shivering or muscle aches, which started with the drug, and stopped more then 2 weeks after stopping the drug.  I am interested to know how many weeks before the symptoms stopped completely and permanently

     

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    • Posted

      Hello... Richard...

      This is probably on aspect on Amlodipine not well understood... it is more than the occasional user that after taking it.. develop serious well being issues. Technically upon stopping ... the drug exits the system ... the effects should reverse ...however... many patients find the onset of other issues ..... so the question begs an answer... is it coincidence or does the mechanism of Amlodipine cause changes which trigger other problems ?

      What this forum collectively points to is that too many patients share this problem but when u go to yr physician ...there is just your case alone and rightly so ... it will never be concluded as anything to do with Amlodipine...

      Here .. you also see that it happens more with Amlodipine than any other bp meds...

      I will try to infer more than this

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