Anyone taking 15mg Mirtazapine with 10mg Escitilopram?

Posted , 5 users are following.

I was initially prescribed 30mg Mirtazapine about 7 weeks ago, was fine for a while, then I had a major family upset which triggered my anxiety, so GP up'd dose to 45mg, this was too much for me and my anxiety worse.

My mental health nurse specialist, got me tapering off 30mg to 15mg Mirtazapine ( 30mg for 3 days then 15mg for 4 days introducing 10mg Escitilopram when down to 15mgs )

I stopped the Mirtazapine 2 days ago and feel horrendous, major panic attacks, shaking, hyperventilating, nausea etc.,

Can anyone give me any advice please, I haven't slept for more than 3-4 hours in 36 hours!!!

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  • Posted

    Hi Karen

    Today was a little calmer than yesterday but still hard work. I'm just doing dinner, pizza! 

    I managed to visit family for an hour. I felt absolutely dreadful the first half hour and thought I wouldn't be able to stay but I talked and felt a bit more 'normal' almost by the end! I was glad I saw them and that I managed it but look forward to the day I actually enjoy something like that again. 

    My son went out mid afternoon and I was worried I'd not cope being alone but I took a diazepam and put on some relaxing music and managed a couple of hours lying on the sofa feeling reasonable. 

    I'm feeling a bit down again now but will force some pizza down and see how I go.

    When will I feel relatively stable again and not have this head to toe anxiety?!

    It's got to get better for us all hasn't it. 

    How are you doing? X

    • Posted

      Hi Nikki,

      So glad you managed to visit your family.

      Also you are eating a little more which has to be a good sign!

      Oh I know what you mean about the anxiety, although it's not always overwhelming it's always lurking grr!!

      I'm asking myself the same questions, how much longer??!!

      I know they say weeks but when your feeling so rubbish you just want to see an improvement!

      I did go to the churchyard today to put some flowers for my mum, something I haven't done in weeks.

      My appetite seems better at the moment.

      But got the dreaded night to contend with soon 😡

      I really hope we see some improvement soon as this is getting me down now.

      Hugs 🤗 

    • Posted

      That's so good you managed to go out to put some flowers for your mum. Bless you. That's amazing.

      Big hugs 🤗 

      So good you're eating too. Honestly I think that's such a good sign. Plus the things you've done lately.

      I pray you will get a little more sleep or a bit more calm tonight Karen X

    • Posted

      Thank you Nikki, I'm keeping my fingers crossed 🤞 

      Hope you have a restful night too.

      Hugs 🤗 

    • Posted

      Hi Nikki 

      Last night was a little better,  thank goodness 😅 

      Had a little wave of anxiety but it quickly passed!

      Was going to try to go for a walk today but the weather here is very wet at the moment.

      Hope you had a restful night.

      Hugs 🤗 

  • Posted

    Morning Karen

    Hey that's fantastic news about your night! That must be such a relief. Another step forward!

    I had a weird night. I normally sleep ok with the Zopiclone but I woke up @3.30 absolutely drenched in sweat?! I think I got to sleep again after a while but it was a bit restless. Hmm. Don't know why that happened.

    But I did have less churning when I woke again. I'm feeling the anxiety again as usual now I'm up. But I feel less fearful. 

    I've got to get my son up and out for 11 as he's going out with a friend and I think I'm nervous about seeing his friend's mum who's picking him up and having that 'how are you?' 'I'm ok thanks' conversation. 

    I'm so pleased you had a better night Karen. That's such a positive. X

    • Posted

      Hi Nikki,

      What is it with 3.30am , that's the time I was waking feeling rubbish when I was tapering Mirtazapine?!

      That's good you had less churning too, a positive that's for sure!

      Oh I hate those " how are you " conversations, always say " yeah, not too bad " .... when I want to say ..." actually I feel horrendous and I'm sick of it " 

      It's another positive that you are feeling less fearful about your anxiety too..... All little positives 😊

      I usually end up playing games on Facebook about 5.30 am lol then go back to bed for a little while after taking a Diazepam!

      I hope your day gets easier.

      Hugs 🤗 

    • Posted

      you are doing well too considering what we are going through.  The anxiety is such a horrid feeling. Yes, i know about the hello,yes im fine conversations, they fill my life.  What on earth happened to saying that and meaning it?   The lowering mirtaz is causing me night sweats and nightmares, dont know how much longer i can do this but people say keep pushing, boy are we all pushing!
    • Posted

      Hi Karen

      Gosh such a rollercoaster today!

      Anxiety seems quite bad again. Just took a diazepam. Maybe I'm expecting too much too soon. I don't know.

      X

    • Posted

      Hi Ann

      Yes, we keep pushing don't we! Finding today pretty hard. Exhausted but anxious! 

      Thanks for your supportive words X

    • Posted

      Hi Nikki,

      I think we all get inpatient waiting for some kind of sign something is changing for the better....I know I do!

      I hate the rollercoaster days,  I take Diazepam during the day too, just to try and take the edge off as they are only 2mg ones.

      Sorry your day is so rubbish. I hope things ease off a bit for you.

      What dose Escitilopram are you on now? And what dose Mirtazapine?

      Hugs 🤗 

    • Posted

      I'm on 10mg escitalopram still (day 11 now) and 15 mirt (day 11 as well after 3 weeks on 30mg).

      I was on this mix for a few weeks before quitting the escitalopram in order to raise the Mirtazipine (my gp was thinking it'd be good for me to just be on one med and I thought it'd be ok) and I didn't feel this bad! My sleep was ok too.

      Am I expecting too much for it to be ok sooner rather than later? Perhaps with each change it's like starting all over. 

      I don't like the way I can't drop off in the day. My head seems to 'dream' when I've got my eyes shut and I'm starting to relax but I'm not asleep. It just comes up with random images and dreamlike sequences?! Does anyone else get that? 

      I try to get by without taking a diazepam in the morning but I think I need to just take it as that's what they're for, to help us through this bit.

      I think I pushed myself too much today as I went out for half an hour even though I was feeling exhausted and I think it caused

      me more anxiety because I felt wobbly and just wanted to be lying down at home.

      It's rainy here too. Did you get out for your walk? X

    • Posted

      Hi Nikki,

      I'm on day 20 of Escitilopram, basically 3 weeks on it now and 2 weeks without Mirtazapine, but I think I tapered and stopped Mirtazapine too quick!

      I found I had really random dreams on Mirtazapine and very vivid and bizarre!

      That's good you went out, another positive, even though you felt wobbly, you managed to do it!

      No, haven't been able to go out, weather is rubbish!

      Been doing chores around the house to try and occupy my mind!

      I wouldn't worry about taking that Diazepam I also need it in the morning and sometimes during the day too.

      I know raising Mirtazapine can cause your anxiety to increase , I was on 30mg and not too bad but when increased to 45mg anxiety went through the roof!!

      Apparently it is one of the antidepressants that can make you feel worse at a higher dose, according to my mental health nurse specialist.

      As we are  all different and react differently to medication , maybe 30mg is too high for you. ??

      Maybe have a word with your Dr?

      I hope things settle this evening.

      Hugs 🤗 

    • Posted

      Thank you Karen.

      I was on 30mg Mirtazipine but it was way too much and anxiety was extreme together with awful dreams and upset tummy, no appetite etc and I'm now on 15mg (been on that for ten days like the 

      escitalopram).

      It was the 30mg that kicked all this off. Interesting what your nurse said about it. I'd never take a higher dose of it again!

      It's good you've managed some chores and are getting by.

      🤗

    • Posted

      I think Mirtazapine has a lot to answer for in making us feel like this!

      I also had no appetite on the higher dose and was constantly running to the loo along with heightened anxiety and bad dreams.

      I'm not sure if the Escitilopram is working or not to be honest, it's difficult to tell with taking the Quetiapine too.

      I hope it is as I can't cope with another medication change.

      Hugs 🤗 

    • Posted

      It has got a lot to answer for hasn't it! 

      I totally understand you wondering about the escitalopram. I will say I've got on really well with it in the past and I've read about people struggling a lot at first but eventually it being brilliant. 

      It is hard to tell when taking these other meds to help but if you feel something is helping a little then I'd try to focus on that and not question it. I know that's hard!! 

      I think my appetite has got a bit worse again. It's not linear is it?! I find I'm sooo hungry and so want to eat but the process of eating is so hard because of my tummy all scrunched up with tension. 

      Hugs 🤗 

    • Posted

      I used to feet the same, hungry but not able to eat, I lost so much weight!

      My stomach was so tense, I felt physically sick all the time which was made worse by the anxiety.

      Do you have any anti sickness tablets?

      When do you see your GP again?

      I'm seeing mine weekly at the moment.

      I'm keeping my fingers crossed with the Escitilopram.

      Hugs 🤗 

    • Posted

      You know I had some anti sickness tablets but got rid of them only recently! Wish I still had them. Began with 'ste...' can't remember the name. 

      My gp said he'd call me, he's only in Thurs and Fridays so gonna see how I am after Wed and make sure I speak to him. I could do with weekly face to face appts really while going through this. 

      I'd say Escitalopram's a good 'un and I'm praying it gets really going for you soon and settles back in for me. X

    • Posted

      What a shame you got rid of them   Maybe your Dr could give you some more?

      Might help you to manage to eat a bit more.

      These Drs are a pain aren't they , mine only works Monday, Wednesday and Friday and my mental health nurse specialist is on annual leave for two weeks!!

      I book my appointments on line and in advance!!

      I'd never get an appointment otherwise!

      I hope you have a restful night.

      Hugs 🤗 

    • Posted

      Yes, I think I'll ask for some more. I was given them last year when I had nausea with dizziness. I hadn't thought of asking for some so thank you!

      I'll also book in a proper face to face appt with my gp whenever one is available next, so I know I've got one. Good plan to book in advance as you do!

      Wishing you an improved night again Karen. X

    • Posted

      Aww definitely ask for some Nikki they might help, hopefully.

      I think a face to face appointment is sometimes better especially if the Dr knows you, they can tell a lot from your body language etc.,

      Hope you have a restful night too.

      Marlene has given us hope too!

      Hugs 🤗 

    • Posted

      Hi, i am finding i need the anti nausea pills some days too.  I dont know whatnthis mirtaz is doing to,me but its horrrible. My nightmares are the worst.  The sickness pills you need are stemetil also called buccastem . My gp gave me some. They work.
    • Posted

      Thanks Ann. I'll ask for some. 

      The Mirtazipine is harsh isn't it. What dose are you on again?

      I'm on 15 now and not sure if I'll be staying on that.

      I hear you on the nightmares! When I was on the 30mg for those three weeks, night times were horrendous with the nightmares.

      I think my sleeping tablets I've been given are masking it now so I don't know if I'll still get them on the 15mg. Going up to 30mg was way too much for me.

      Sending a big hug 🤗 

    • Posted

      I can reassure you both that the nightmares do stop, it's definitely the Mirtazapine causing them!

      I don't have them anymore so there is hope for you both Nikki and Ann please be reassured.

      Hugs 🤗 

    • Posted

      Thank you Karen.

      I never had them before I upped to the 30mg! Terrible side effects from that! I'm really hoping I can tolerate being back down to 15mg in combo with the 10mg

      escitalopram.

      I woke with reduced churning again today. It's still been ongoing since I've been up though.

      I've phoned my gp surgery and asked if a gp can call me as I want to ask for some anti sickness tablets. 

      Fingers crossed X

    • Posted

      Hi Nikki,

      Oh I hope your GP rings you back and gives you some anti sickness tablets, they might hopefully calm the nausea etc down!

      I had a few waves of anxiety earlier this morning but they soon passed.

      I've just waly3/4 mile to my local supermarket, and walked around getting a few bits and walked back.... by myself!! Nearly turned back a few times but persevered!

      Hugs 🤗 

    • Posted

      Hi Karen and ladies

      I've not been on much today, haven't been feeling good at all. I seem to be a bit more depressed today. What's going on? Is this part of the rollercoaster?

      I spoke to my gp and he's prescribed some anti sickness meds. I've not been able to get out for them but I've asked my dad to pick them up this eve.

      He also said he doesn't think meds are going to do it all for me and I need some talking therapy too. This threw me into a downward spiral really as although I know there aren't any magic 100% pills I am still hoping the meds will really help.

      I'm trying relaxation but my mood has been so low I find it hard to benefit.

      I tried a sleep but just got too many upsetting thoughts. Why are these coming up so much (about my separation 5 years ago!) at the moment? 

      Does anyone else get the depression too? I seemed to go down a few hours after taking a diazepam. They've made me tearful before.

      I'm worried that I'm getting worse but can't see how that can be.

      I'm so happy for your trip out today Karen, that's brilliant, and the anxiety passing. It does give me hope. 

      Sorry to go on and I just need to share and see if anyone has experienced the same stuff. X

    • Posted

      Hi Nikki how long have you been on the medication?l know you have a lot of bad days for the first 3 or 4 weeks then you should have a few good days.Try not to despair you are more sensitive to what people say as you are feeling very unsure and vulnerable.Just keep going and know these are just side effects and the brain is just adjusting to the meds.You will stabilise but l do agree with your father therapy is always the best course of treatment with medication.That doesn't mean the medication isn't going to make you feel a lot better.You are having a bad day tomorrow may be a lot better.

    • Posted

      So sorry your having a rough day Nikki.

      I'm glad your GP has given you some anti sickness tablets though.

      I have gone through phases of feeling depressed this is mainly for me about my mum and my breast cancer, I find myself lately reliving the last days with my mum I think it's because these things are still deep rooted in our subconscious?

      I've tried talking therapy twice now, both times it was done over the phone, the first time I think it helped a little but the second time I stopped it as I was going through this tough time and it wasn't something I could concentrate on.

      I wish they could send a community therapist out as I think face to face might be more helpful.

      That's why when I was seeing the private counsellor I felt it was more beneficial.

      I do believe that medication alone is not the answer but should be used with therapy too.

      It's getting the right therapy that I find the problem.

      I hope the anti sickness tablets help and things settle for you.

      Sending hugs 🤗 

    • Posted

      Forgot to say diazepam can increase depression so use it sparingly.
    • Posted

      Hi Marleen, it's been 11 days I've been on this combination. Before that I tried 30mg Mirtazipine for three weeks and it was horrendous. Though the depression lessened, the anxiety was relentlessly high. So my gp put me back on this combo that I had been on before (and didn't feel this rough!). 

      You're right, I do feel v vulnerable. Thank you for reassurance me X

    • Posted

      Don't worry Nikki it's probably more lowering the dose that will pass and things will settle down.One day at a time.You can do this

    • Posted

      Thank you Karen.

      I think you're doing so well and being so supportive thank you.

      I agree, a community therapist would be brilliant. I'm looking into some therapy though I was meant to be hearing from the Community Team about something. I will call them I think. I too think I would benefit most from face to face counselling.

      Hopefully I'll be able to enjoy some food a bit with the tablets. I think it will help my rest if I can eat during the day.

      Gosh so sick of feeling so rough in all directions.

      Bless you for your support ??

    • Posted

      Thank you Marleen. 

      I only took one diazepam today. I hope I can do without them soon. 

      I couldn't see the wood for the trees today. Full on!

      Really hoping tomorrow is a bit less intense!

      X

    • Posted

      Aww Nikki,

      You are a great support to me too ??

      When my mental health nurse specialist is back off leave I'm going to ask him about community mental health visiting, the talk therapy is not right for me at the moment, I hope he understands this.

      Hugs 🤗 

    • Posted

      ??I'm glad I'm some help. I love helping others, I wish I was able to do more.

      I kind of feel the same about talking therapy right now to be honest. I feel like I just need someone to listen to me and reassure me, boost me up a bit, tell me it's going to be ok, etc Support rather than anything heavy. 

      I'm sure if you express it's not right for you at the moment he'll listen. That's a good plan Karen.

      🤗

    • Posted

      That's exactly how I feel too, just want support etc. 

      Have you taken your anti sickness tablets yet?

      I hope they help you.

      Hope you have a restful night and tomorrow is a.better day.

      Hugs 🤗 

    • Posted

      I took an anti sickness tablet just after 9. Only just got them. I felt a bit weird, then sleepy. Will try one in the morning.

      Is that how they made you feel? X

    • Posted

      I'm not sure which ones I had , but yes they did make me feel sleepy.

      I think mine.began with a 'P' ?

      Hope they help and you get a restful night.

      Hugs 🤗 

    • Posted

      These are Stemetil (prochlorperazine). The same ones I had last year for nausea. I'd forgotten how drowsy they make you!

      I hope you have another better night Karen.

      Here's to better days to come ??

    • Posted

      Yes that's the ones I had too! 

      As you can see up at stupid time again ggrrr😡

    • Posted

      Hi Karen

      I'm sorry you woke so early again. I read your post earlier and came back on to reply but sometimes find it hard to locate posts again, keep scrolling to find them!

      I've had my usual kind of morning, waking with a little less churning, then restless, then get up and anxiety goes right up. I did a bit of breathing and although it was a struggle, things eased a bit for a short while. Just longing not to feel so tense and restless all the time and when I try to rest my head starts buzzing with random thoughts!

      How are you getting on? X

    • Posted

      Hi Nikki  ,

      I'm finding it hard to find posts sometimes too have to scroll to find them lol

      Not the best of days for me either, obviously was up mega early, went back to bed but felt very shaky, and kind of shaky inside too??

      Got back up again and after I took my Quetiapine I went back to bed and slept for two hours.

      Thought I'd turned a corner yesterday but today is rubbish again.

      I hope things calm down for you today and the anti sickness tablets start to work.

      Hugs 🤗 

    • Posted

      Hi Karen

      Oh no, that's horrible for you. The inner shakiness is exhaustion I reckon. I get that sort of feeling too.

      Why does it have to be so tough to see progress? 

      I can see though that you have made progress even though it feels you're not. It's so hard when we're in it and going through the pain of so much variation and difficult symptoms.

      I'm sending you a big hug 🤗 X

    • Posted

      Thank you Nikki,

      I'm going to mention all this to my GP on Friday see what he says.

      Maybe I'm just inpatient....... well I know I am, guess it's just that we want to feel right again?!

      Don't think I could cope with another medication change especially if it was one that was new to me!

      I never thought of the inner shakiness being exhaustion, you could be right!

      Sending massive hugs 🤗 to you too

    • Posted

      I understand about the thought of another medication change. I'm hoping and praying this is going to settle for me and I can start to recover, have that foundation to build on you know. The same for you too. Maybe it is just the case of sticking with it (I remember reading about that lady in another forum who got there in the end after sticking it out for weeks and weeks) but it's so tough.

      I don't think it's impatient to want to feel better. 

      It'll be good for you to talk about it all with your GP on Friday.

      I'm feeling a bit like I can't talk to my GP for a while as he doesn't want me to make any more changes for now. 

      I'm hoping I won't have to change anything else, like you. 

      This is such a blessing having this forum X

    • Posted

      Oh gosh this forum and the people on it are so supportive and helpful!

      I seen posts where people have said it's worth riding it out too, but like you said so difficult when your going through hell !!

      I doubt my GP will change anything at the moment, I was meant to take 3 Quetiapine in the morning and 3 at night, but found when I was doing that I didn't sleep, so went back to 2 in the morning.

      Will talk to him about that too!

      I better write a list lol 😂 

      Hope your feeling a little better.

      Hugs 🤗 

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