Aquablation for BPH
Posted , 38 users are following.
Very promising new treatment for BPH now in clinical trials (Water Study):
PROCEPT’s AquaBeam combines image guidance and robotics to deliver Aquablation, a waterjet ablation therapy that enables targeted, controlled, and heat-free removal of tissue for the treatment of lower urinary tract symptoms as a result of benign prostatic hyperplasia (BPH).
2 likes, 366 replies
jimjames tom86211
Posted
Informative video on Aquablation on the Procept Biorobotics website summarizing a Phase III study comparing Aquablation to TURP. 181 men enrolled.
Unlike Gilling's Phase I study, (under 40 men), which should no incidence of retrograde orgasm, this study makes no such claim, and interestingly, unlike the Phase I study, doesn't even use that terminology, suggesting the role of marketing forces in how these studies are presented!
The closest I could find regarding retrograde orgasm, was this slide near the end of the presentation, which read in part " Aquablation preserves ejaculatory function and continence to a greater degree than TURP". Not very assuring for those hoping that Aquablation would be free of sexual side effects.
Hopefully, there will be some more precise clarification.
Jim
jimjames
Posted
TYPOS:
Second paragraph should read in part "...which showed no incidence
of retrograde ejaculation..."
jay111 jimjames
Posted
felix1956 jimjames
Posted
I had the Aquablation procedure last Sept 20th, here in Southern California. Unfortunately, I had a retrograde orgasm, today. It is something that all men have to take into account. Don't believe that the "Aquablation" procedure is "retrograde" safe, it is not.
jimjames felix1956
Posted
Hi Felix,
When you say, "last Sept 20th", are you talking about 4 weeks ago? If so, let's hope you will regain normal ejaculation with more time.
Jim
kenneth1955 jimjames
Posted
grant75607 tom86211
Posted
mikemh grant75607
Posted
Best of luck. I was a possible candidate for a trial in UK too, but I have held on with what I have got for now.
Really interested to know how it goes
Mike
uncklefester grant75607
Posted
They're running a new trial here in the States. Last trial there was a chance you would have TURP done since it was a double blind study. This one looks like its just Aquabation. In the end its another form of TURP but it does seem a little more accurate since its computer guided
grant75607 mikemh
Posted
mikemh grant75607
Posted
Mike
Camster mikemh
Posted
grant75607 mikemh
Posted
mikemh grant75607
Posted
mikemh Camster
Posted
Not so easy to answer. I certainly didn't have as many problems as I do now before Urolift, but Urolift has done its (perhaps temporary) job of keeping me going without drastic surgery
kenneth1955 grant75607
Posted
Grant. Read up on it first. The 3 trails they did do not say alot about retro but it is close 10% can you live with that 10%. Doctor will tell you lesss because they are trying to sell the procedure But i guess its better then a turp Also there is a 5 years study that was just out on urolift 0% retro and all patient are still going strong. I'm going on 2 1/2 year all is great Good luck Ken
grant75607 kenneth1955
Posted
kenneth1955 grant75607
Posted
Yes think about it first. It will be to late after it done and you have retro. Try the Urolift first you can always have the other. And you know they do the same make a tunnel. I'm very happy with mine and no side effects....Take it easy and good luck Ken
mikemh grant75607
Posted
grant75607 mikemh
Posted
jimjames grant75607
Posted
Hi Grant,
Ask you doctor to show you where he gets the 4% retro figure? The Phase II and Phase III trials show a retro rate of 25% of TURP. Realistically, that would put the retro rate of Aquablation between 15 and 20 per cent. Also, make sure you ask if there is a control arm to the study. In the U.S. the control arm was TURP, so that meant going into the surgery you didn't know if you were going to get a TURP or Aqualation.
Jim
kenneth1955 jimjames
Posted
grant75607 jimjames
Posted
kenneth1955 grant75607
Posted
Grant Please read everything before you sign anything. Most of the time it one procedure against another 20 to 25% retro was in the trails Read all 3 again. It 's not worth taking a chance with something your not going to be happen with. Please Ken
jimjames grant75607
Posted
Grant,
"No heat" may account for 75% less chance of retro than TURP per the Phase II and III trials, but that still translates into a 15-20% chance of retro. Just because your doctor tells you it's 4% doesn't make it 4%.
Jim
grant75607 jimjames
Posted
grant75607 mikemh
Posted
mikemh grant75607
Posted
Slightly complicated answer - sorry! Prostate size about 80cc - possibly too big for Urolift (the man said).
Had NHS Urolift at Frimley August 2015. Had issues with some pains and eventually paid for him to look see privately. He found one tag problem, took it out and put 3 more in, ending up with 9 tags - almost a record. That was Jan 2016.
Since then the flow is tolerable most of the time, but I would like it to be better - especially at night.
I have been suffering with prostatitis too for some time, which clouds the issue.
I have posted my day by day Urolift experiences on this site somewhere - not pleasant reading - but I think I was unlucky
grant75607 mikemh
Posted
kenneth1955 grant75607
Posted
mikemh kenneth1955
Posted
Kenneth. I know you are well intentioned but you are putting a lot of pressure on Grant to do as you did. We are all different. That fact that you only have 4 implants (I have 9) shows your prostate is much smaller, so Urolift is more applicable to you.
?Grant should consider his own situation.
Reading this forum, I get the feeling that in US there is a great deal of distrust of Urologists. In the UK we don't feel they are so bad, and that they have our best interests at heart.
jimjames mikemh
Posted
I didn't sense Kenneth was putting "the screws" on Grant but you bring up a very good point. There is a tendency here (and elsewhere) where men try and convince others to do the procedure that worked for them and conversely to avoid a procedure that didn't work. This is more human nature than scientific.
Like you said, "consider (your own) situation" because it may not be a good match for someone else's. And that's why while anecdotal data is helpful, it should also be pared with trial data. And the trial data again, should be compared to your own individual situation as trial participants themselves are often cherry picked.
Jim
kenneth1955 mikemh
Posted
Im sorry if it like I'm doing that. I am just trying to get him to think about what he is doing. Why have your prostate cut out when having it pulled apart may work just has good and has no side effects. Doctor don't worry about side effect there not the ones that have to go through them. You have to look at the pros and cons of any procedure you have. You also have to remember that doctor don't know if a procedure will work until it's done. You have it cut out they it's to late. Life is to short to give up on your prostate Ken
grant75607 mikemh
Posted
kenneth1955 grant75607
Posted
Grant I know its a hard discision to make. BUT don't let them diside for you because it takes longer to a appointmants. To me it seams like you have to take what they are welling to give you. And you and your concerns don't matter. Just be carefull Ken
mikemh grant75607
Posted
I wonder whether you went through with the Aquablation trial in August. How did it go? How are you?
Mike
jimjames grant75607
Posted
------------
Really? Based on what. Read my previous comments on the phase III data for a more realistic expectation.
Jim
grant75607 mikemh
Posted
Grant
nealpros grant75607
Posted
Perhaps the doc knows how to do Resum, and has bought equipment to do it,but doesn't know anything about Urolift . Get another opinion.
Neal
kenneth1955 grant75607
Posted
dave10869 grant75607
Posted
Dave.
kenneth1955 grant75607
Posted
HEY Grant......October is just around the corner. I had a very slow stream before I had my Urolift. Had a scope done the doctor could not get the camera in my prostate. After he opened me up with the Urolift I have no problem. 2 1/2 years. I hope you make the right pick for you. Don't do anything your not sure of just because your due to have it done. Ken
grant75607 dave10869
Posted
Hi sorry I don't know the latest figures my uro just says low! no actual figures until after the next trials I guess.
grant75607 kenneth1955
Posted
Thanks Ken, It's the only thing I can think of at the moment! .
jimjames dave10869
Posted
Dave and Grant,
Check out the Phase III presentation on their website for the retro figures. I would not call them "low" at all. From memory, the incidence of retro was around 30% of the control (TURP) group. Even taking very conservative figure of retro in TURP (60%) that would mean 20% retro in the aquablation group. You will find a lower number (8% again from memory) in their presentation, but I don't see how it's possible that the TURP group only had 24% retro. More likely, they came up with a low retro figure due to a faulty questionnaire and/reporting.
Jim
kenneth1955 jimjames
Posted
mikemh grant75607
Posted
Hi Grant
What's the latest with you? Did you decide on Acquablation or .....?
?I am considering it still ...
Best
Mike
grant75607 mikemh
Posted
mikemh grant75607
Posted
Did the main man do it at Frimley?
Mike
grant75607 mikemh
Posted
mikemh grant75607
Posted
Well, I had the phone call today, giving me a date in a few weeks for the aquablation. So now I have to make a decision whether I go for it or I carry on as I am.
I have a 123cc + prostate, I have 9 pairs of urolift clips in there. I have a small bladder (possibly only 300cc), and have urgency and frequency issues. Sometimes I go every hour throughout the night, but sometimes only once: totally depends on how much and when I drink. My flow is poor, and perhaps is slowly getting worse, but sometimes it seems to flow really freely. I have been living with these issues for years and somehow manage around them.
I may make a list of pros and cons...
Maybe I will end up being 'normal' - but somehow I am pessimistic about that, as it is difficult to imagine after all this time that I will be able to put off peeing for ages like 'normal' people. But my prostate seems to keep growing so I am scared I will have full retention. I am also worried that my case is extreme with so many urolift clips and such a large prostate, so that the operation may have issues. Of course, I may end up with RE after all, or worse ... but I cannot see anything else that can help me coming along.
kenneth1955 mikemh
Posted
Mike I think you should do pros and cons. The urolift has keep you open and it did what it is suppose to do. What I am worried about is that I don't think it is your prostate. You still will only have a bladder that will hold 300 cc I don't think getting rid of the prostate is going to solve your problem. It is a lot to think about. The water aquablation is just another way of doing a Turp. You have a hard decision to make I wish you all the best God help you Ken PS What did the doctor tell you. Did he give you any odds
dave10869 mikemh
Posted
Hi Mike, I can understand this is a difficult decision for you. Perhaps best to speak to your urologist again first. Run your concerns past him and try to get more info as to the results he has achieved to date as to RE etc with other patients on the study. Perhaps you would keep us informed as to what you decide please. I have a vested interest in as much that I too have a gland in excess of 120 cc but no urolift clips fitted. I put my 300cc bladder capacity down to the size of the gland. I am in the UK & think I may possibly have seen the same urologist in Surrey as you where I first learnt of aquablation. He told me that he had operated on glands up to 140cc to date, this was some months ago before the current study began. Good luck. Dave.