California rocket fuel

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Has anyone tried the combination of Mitrazapine and Veneflaxine?

Would like to hear your opinions

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15 Replies

  • Posted

    Hi kerry

    I'm 10 days in. Can see some improvement already. How long have you been on it, or are you just starting?

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    • Posted

      Hi Lorraine

      Thanks for your reply. Im currently taking Mitrazapine and Citalopram. My prodoc said to stay on this combination until a week on Tuesday and still if no improvement said we can replace one of them. It was suggested to me to ask about venlafaxine. So you say you can see an improvement thats good to hear!!

      Xx

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    • Posted

      Hi kerry

      Sorry for the delay i couldnt access the site for some reason. The only side effect has been sporadic palpation the first few days. Today I have a slight tremor in my hands. It has been very easy so far. I felt instant improvement. How are you getting on?

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    • Posted

      Aw don't worry. Oh so you sound like your doing really well. Well to be honest not so good don't seem to be getting the medication thats helping to lift the depression. I'm still crying and just feel low. So you felt the instant lift then?

      Xx

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    • Posted

      Hi kerry

      on the second day I started to feel better. I had been on mirtazipine for two months before the venlafaxine was added. How long is it for you? You sound really down and I know how bad you are feeling. This illness makes you think you won't get better. I assure you, you will get better, it's just about a little more time and finding the correct dosage. I cried buckets and thought I was going out of my mind. Mirtazipine helped lift my depression but when venlafaxine was added, it made me feel 90% normal. I just need to establish a routine and build up my confidence again and then it will be 100% better.

      You will get there too, I promise you. What meds and dosage are you on and how long have you been on them?

      Thinking of you♥

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    • Posted

      Hi Lorraine

      Your right there i feel like im never going to get there. I had 3 good days when mitrazapine was added to the citalopram and then nose dived with a bang. Felt normalish on those days and thought we had found the correct dosage 20mg cit and 15mg mit. This will be my 10th week just want to get back to my life. Not been to work in all this time either. Thats what people keep saying i will get better finding it hard to believe as i'm sure you can understand. It does knock your confidence doesn't not want to go out or see people etc.

      I'm currently on cit 30mg and 15mg mitz and they have been changed almost every week when i see my prodoc. I've almost exhausted all options of cit and mitz togther now. My prodocs pretty good so hoping rocket fuel combination maybe something i can ask him about.

      So nice to hear a sucess story!!! I bet you feel so proud of yourself. What dosages are you taking?

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    • Posted

      Hi kerry

      i took citalopram for six months and didn't get better. I came off cit in December and started Mirtazipine which really helped 15mg but I was still exhausted, not socialising and really irritable. Only since the combo of mirt and ven 75mg has life got much better. I'm only ten days in but now enjoying my family again. My confidence is shot as i have been unwell for a year now. But onwards and upwards! If you can give this combo a try, I cannot believe what a difference it's made in record time. Don't lose hope (I nearly did) this illness is cruel and relentless but, you will beat this and you will get better. I kept thinking I was the exception to the rule eg. Others get better, but I won't. This is the depression tricking your mind so you start believing it. In addition the mind sends signals to other parts of our body, which leaves us with aches and pains and tummy issues. It's hard to truly believe you will get better. But you definitely will.

      I'm here anytime for you ♥♥

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    • Posted

      Hi Lorraine

      I have found that i can be very irritable at times too. I have to say that this is the worse thing ive ever gone through. I've been really lucky that i've had good support from family and partner. Being an exception to the rest sums it up in one!!. Normally im very happy and enjoys life so im struggling to understamd why i am the way i am. Aw im so pleased your starting to enjoy your family that must be so nice for not only you but your family too. Thank you for your reasurance smile xx

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    • Posted

      Hi kerry

      the irritability will disappear as you start to properly recover. Let me know how your doing from time to time. ♥♥

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  • Posted

    I know you posted your question 6 months ago, but I'm answering now anyway. I'm 68 years old and had no history of depression. Last July I was diagnosed with MDD with psychosis and have been taking 300 mg of Effexor and 15 mg of Remeron since then. I just found out that combination is also referred to as California rocket fuel. It works great for me. I'm happier than I've been in years and sleeping better too. I do have a couple of side effects, high cholestrol and some parethesia, but I think it's worth it not to suffer from the crippling depression. I hope you find something that works as well for you.

    Good luck,

    Phyl

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  • Posted

    I'm on Buspar an cit, but have been thinking of switching myself cause the cit has not done much for me then when Buspar was added I got two good days then crash again almost back to the beginning my next appt with my dr is November 4th and I'm thinking about asking to be switched to veneflaxine which I believe is the generic to Effexor? If that's the case I have been talking to a lot of people that say the mixture of Buspar and Effexor has literally saved their lives and honestly I'm so fed up with how I've been feeling I almost took my self off all meds together as atleast I'd know how I'm feeling and what was the medicine making me feel like

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  • Posted

    I am new to this forum but have seen this old thread about the combination of mirtazapine and venlafaxine

    I have been taking a maintenance dose of mirtazapine for over a year to get me through some difficult times. I have recently experienced severe anxiety and my Gp gradually increased this to the highest dose with no effect. On the advice of a psych I started taking low dose of venlafaxine while reducing the mirtazapine over a period of two days. My anxiety got so much worse after just one tablet (pounding heart, trembling) that I stopped. The doctor wants me to try again after a week on lower dose mirtazapine but I am really scared. Has anyone else experienced this reaction?

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