Denosumab problems
Posted , 13 users are following.
Discontinuing denosumab (Prolia) can lead to vertebral fracture, apparently not related to the underlying osteoporosis, but to the development of microcracks in the bones from denosumab. Advice is to replace denosumab, not go cold turkey off the med. Sounds like this drug is ripe for lawsuits, and perhaps should be discontinued.
https://www.ncbi.nlm.nih.gov/pubmed/27732330
2 likes, 72 replies
Spindles Anhaga
Posted
I was put onto bisphosphonates like Actonel and alendronic acid back in 2004 and after seven years I stopped for two years but in that time I slipped in the garden and fractured my femur so was put back on them for another three years so in total was on them for ten years but stopped again a few months ago. I have have recently found out that bisphosphonates can cause small femur fractures called atypical femur fractures. It's supposedly a "rare" condition but not if you read articles on the internet! I have been told never to take alendronic acid again, I can't even have denosumab as that's the same stuff and the treatment for the tiny (at the moment) femur fracture is a metal nail and screws, something I already have in the other leg. Doctors have known since at least 2004 about fractures caused by bisphosphonates but they still dish them out. If I knew then what I know now I would have refused them, especially as my T scores weren't that bad. Anyone on bisphosphonates who has aching, mainly in their thighs but also their hips or pelvis should get themselves checked out as this can be an early sign of an atypical fracture and can go on for weeks or months before finally fracturing with very little trauma.
Anhaga Spindles
Posted
I am so sorry you've been having these problems. Someone posted on a thread on another forum - poster asked if anyone had increased bone density without medication. Several people had, and I was most struck by someone who had turned around her bone density to a point that no meds were recommended any more, simply by a few supplements and walking her dog! She started with osteoporosis in the spine, I think, and osteopenia in the femur, or was it the other way around, and within a year improved the osteoporosis to osteopenia. This is also what happened to a friend of mine, So the point I'm trying to make is that it seems, if the OP is not too far advanced, it's almost too easy to improve bone density. Why are the doctors still so intent on pushing the OP meds at us? I do know of others with much worse readings who have refused the meds and tried a little harder with the nutrition and exercise and they too have done well.
Do you think that by doing all the "natural" things it will help your bones to heal?
alison28608 Anhaga
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kathleen65757 Anhaga
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Thanks for all your research. It is much appreciated by many of us.
The choice remains with the patient and no one is forced to take one path or the other.
It is good to be flexible too, choose the course for you at a particular time.
Anhaga kathleen65757
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Yes I was struck by how easily this particular person had turned things around so it makes it even more imperative that two things happen: younger people, especially women but men too, be taught about how to care for their skeletons the way we receive advice about avoiding heart and lung conditions and diabetes. Then we should be monitored after midlife, and promptly given advice about nutrition and exercise before any bone thinning becomes dangerous. Just think how much money would be saved, not to mention suffering avoided!
Anhaga kathleen65757
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kathleen65757 Anhaga
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As I have said a few times on here I know women who have never had a scan and are blissfully unaware. I envy them.
Being aware I now do everything I can to help improve my bone health.
Where it goes from here now for me only time will tell.
Anhaga
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alison28608 kathleen65757
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alison28608 Anhaga
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kathleen65757 Anhaga
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Anhaga kathleen65757
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And a Happy Easter to you, too, Kathleen!
We've had snowdrops for a little while now, but today our crocuses put in an appearance. 😊
kathleen65757 Anhaga
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Anhaga kathleen65757
Posted
We keep getting howling winds. I'm sure it's worse than it used to be. But could be my memory is faulty!
kathleen65757 Anhaga
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