Doxazosin

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Hi, just been prescribed Doxzasosin for my high blood pressure. Brief comment on the note with the meds that this is also used for treating an enlarged  prostate ( one of my many ongoing problems) has anyone any comments on this drug, good or bad. Glad to hear anything you can contribute.

I have drug resistant high BP, this is the latest for me to try.

Have intermittent prostatitis since having a prostate biopsy, episodes usually lasting a few days at a time. Up 2-3 times in the night to go to the bathroom. always have a poor and splitting stream. This has never been good from being a kid! Going for pelvic xrays  in the morning, started with low back pain and pain in and around my pelvic area with a tender spot on my hip. Age 67. Its rubbish

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  • Posted

    I taking 4mg Doxazosin for BPH and the most significant side effect is RE (retro ejaculation).  It did helped lowering my BP. It will help you with your nightly trips to the bathroom and your flow. Hank

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  • Posted

    I took one of the similar drugs Tamsulosin some years ago that I soon stopped due to the sexual dysfunction it was causing. If you ever need cataract surgery it makes it more difficult as it causes floppy iris syndrome.  
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    • Posted

      "All alpha blockers, including doxazosin, can cause intraoperative floppy iris syndrome (IFIS), but doxazosin less so than tamsulosin. " Hank

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    • Posted

      Derek I was told by an eye surgeon that they can work around if they know, plus if you stop taking it for a week or so and it's out of your system it's OK to have the surgery - have you heard otherwise?

      I think Tamsulosin is not the same type of drug anyway, it's not for lowering blood pressure. I took Prazosin once for BPH, it's a related drug and it lowered my blood pressure with no sexual side effects whatsoever. In fact it lowered it too much - Prazosin also known as "minipress" I believe if i remember from Australia.

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    • Posted

      Tamsolusin is of the same family and is also an alpha blocker and lowered my BP.

      The effect on the eye/eyes stays when it is out of your system according to my surgeon who commented why do they give me all the awkward ones. In my case it had only effected the right eye. I don't know if there was a connection but that eye developed PCO and I needed later laser surgery. 

      I once asked the practice nurse if Amiodarone was the most complained about drug prescribed. She said No it's Tamsulosin. Yes, by men I replied. No, she said by their wives.

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    • Posted

      Not sure how true the stories are about the meds, since most of the people taking them are in the age group that may be cause for lower sex drive. I take Tamsulosin, 2mg and it did not affect my BP or sex drive.
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    • Posted

      well Derek says not, my surgeon was clear that if they know you are on Tamsulosin they can still do the surgery, and it helps to stop a week or so before, though he didn't say outright "IFIS is reversible"

      I'd be interested in seeing some research on it.

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    • Posted

      I had stopped taking it a considerable time before I knew that I was going to have cataract surgery,

      Wiki says, Intraoperative floppy iris syndrome (IFIS) is a complication that may occur during cataract extraction in certain patients. This syndrome is characterized by a flaccid iris which billows in response to ordinary intraocular fluid currents, a propensity for this floppy iris to prolapse towards the area of cataract extraction during surgery, and progressive intraoperative pupil constriction despite standard procedures to prevent this. 

      IFIS has been associated with tamsulosin (e.g., Flomax), a medication widely prescribed for urinary symptoms associated with benign prostatic hyperplasia (BPH). Tamsulosin is a selective alpha blocker that works by relaxing the bladder and prostatic smooth muscle. As such, it also relaxes the iris dilator muscle by binding to its postsynaptic nerve endings. Even if a patient has only taken tamsulosin once in their life, that dose is enough to cause IFIS during cataract extraction indefinitely Various alpha-blockers are associated with IFIS, but tamsulosin has a stronger association than the others.

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    • Posted

      So Derek did you have cataract surgery? How did it go and did the surgeon say Flomax made it harder for him to perform surgery?
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    • Posted

      The left eye was done first and was evidently quite straightforward. The right eye done three months later by a different surgeon at the same hospital gave rise to comments on floppy iris syndrome and why was he given all the difficult cases. So far as I was concerned the end results were no different and coincidence that the right eye later developed CPO and needed a  laser procedure. 
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    • Posted

      It's good to know that they were able to have a successful outcome with you - I suppose that confirms what my surgeon said, it was probably one of his assistants who claimed it's reversible if one stops taking it, I think my surgeon said they just need to know ahead of time. I don't remember because I was in pain from him fixing a small retinal tear which was very close to a nerve.

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    • Posted

      Where it says that one tablet can cause it makes it rather dramatic. Quinolones can also have a bad effect in a very short time on some people.. 
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  • Posted

    Not the desire but causes RE and reduced erections when taking it but recovers when you stop.

    Get one a day Cialis that will help the flow better.

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