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donna30993 donna30993

Feeling worse after 6 weeks on Fluoxetine.....is this normal??

Hi

​I started 20mg fluoxetine 6.5 weeks ago, and increased to 40mg 2 weeks ago.  I am starting to feel worse the past few days, anxiety is awful, low mood and no energy at all.  Is it normal to feel this at this point? as I thought I would be improving, not getting worse.  Should I stick it out or come off?

​Any advice would be much appreciated.

​Donna xx

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  • karen60759 karen60759 donna30993

    Hi Donna, yes this normal especially after you've increased the dose, you get some side effects again, I've been on 40mgs almost 5 weeks now, after increased from 20 at 10 weeks, and it still hasn't settled for me, though I've been on it before so it takes longer, I do get some really good spells, and then the symptoms come back again, which has happened this week, bad morning anxiety which is so awful! But I know these meds work they just take a long time and can be very up and down in the first week weeks/ months so just hang in there x

    • donna30993 donna30993 karen60759

      Hi Karen

      ​Thank you for this reply.  This gives me hope that things will improve in time.  I dont understand though why I am still having these affects 2 weeks after increasing the meds, as I read that it usually only lasts a few days? I had a meltdown at work today, tears the lot....but I must say i actally feel better for it.  Well, a little better anyway.

      ​Donna x

    • karen60759 karen60759 donna30993

      Hey, if you read through the posts on this forum you'll see that this med takes a good few weeks and often months to fully work with ups and downs all the way, it's because you have to wait for the receptors in your brain to accept the increased seratonin instead of fighting it by shutting down - which is what causes the increased and intermittent anxiety, so for now just try to accept its short term pain for long term gain, and try to cope with it through relaxation, excercise or therapy by coming on these forums - that's what I'm doing anyway x

    • danny37079 danny37079 donna30993

      Hi Donna,

      I was reading this post from last year and was wondering how everything worked out for you? I’ve been on flu for 4.5 weeks total now on both 10mg and now 20mg. Last few days have been a struggle. Sad thoughts, high anxiety and not enough sleep. I recently went back to work after months away and it’s been so difficult getting in a groove again . Most days I want to quit but i don’t. Things I took for granted are now so hard to do like driving in traffic etc. I hope this med worked for you. Any feedback would greatly help me. Thanks 

    • danny37079 danny37079 amy05881

      Hello, yes it’s a struggle. I’ve been much better lately but I know it comes and goes. I expect that all side effects like headaches will be gone in the next 2 weeks. Stay positive. I suggest increasing to 20mg around day 14. Best of luck! Any questions pls don’t hesitate.

    • danny37079 danny37079 amy05881

      Hang in there. Yes the first 4 weeks were up and down for me. But now around week 6  I’m finally feeling close to normal as ive been in months.  Hang in there i promise it will start taking full affect very soon.  There are days the anxiety is higher than others but Around week 5-6 you will  see a huge change. Best of luck!

    • amy05881 amy05881 danny37079

      Thanks Danny I'm only on 10mg at the moment don't think I will increase my dosage yet got an appointment Friday with the docs it's just these side effects are so hard where you sweating a lot and feeling more anxious and jittery thanks x

  • luci11 luci11 donna30993

    Hi Donna,

    yes I think it is normal, the increase is a little like starting the drug all over again - the side effects are there. I would recommend that you stick it out, give it some 12 weeks to feel better, and hopefully also after 8 weeks or so you will start getting some good days too. I know it is so discouraging when one feels worse taking the medication than before it, it makes such little sense, but sometimes they make you feel worse before you get better. I am happy I stuck with mine, now at 10 weeks I am feeling much better, not perfect or 100% recovered but I would say already better than before the meds. Of course blips are still there sometimes, but I am hopeful. Have you had any good days yet or at least couple of hours or so during some days? When is the anxiety the worst? Mine was always the worst in the mornings, afternoons I started feelling little calmer in weeks 5-6.

    Luci x

    • donna30993 donna30993 luci11

      Hi Luci,

      ​It sounds like you are feeling better today, which I'm very pleased to hear!

      ​The thing I don't understand is why Im feeling worse everyday 2 weeks after the increase, as I thought it would be getting better after a week of increase?  Even my mood is low, I burst into tears at work today as my workload is horrendous, but I did actually feel slightly better afterwards and my collegues were very supportive and understanding.

      ​I think I am going to try and hang in there for at least 12 weeks of taking these meds, as you suggested.  I'm so glad I have found this forum as I have nobody else I can talk to that truely understands how I'm feeling.

      Donna xx

    • luci11 luci11 donna30993

      There is nothing to understand, it's how this medication sometimes works, it makes you feel worse before you get better. If you try to read a little about how SSRIs actually work, what changes they are making in the brain and how confusing it is to the brain at first too, it could help you to make more sense of it - it certainly helped me...in short the brain is confused too with these new serotonin levels that it does not produce but it takes the brain long time to understand what it needs to do...it even temporarily stops producing its own serotonin (because getting it externally from the meds but it thinks it is its own) and that is what causes the low moods, until the brain learns again that it still needs to produce its own...for everyone the process is different but in most cases it just takes time....

      Happy to hear you will still give it a go, it is really too early after the dose increase, you will get better eventually!!! smile

      And good that your colleagues are supportive. We all need to ask for help sometimes and there is no shame in being vulnerable at times. Everyone is.

      Yes the forums are amazing. I am so grateful too. I would feel completely crazy if I didn't have others for support and knowing they go through the same.

      Luci xx

    • karen60759 karen60759 lookingonwards

      Hi looking forwards- hope all is well? When did you see improvement after increase to 40mgs? I'm almost at 5 weeks after increase and have had some good weeks but the past couple of weeks have been pretty tough, especially with anxiety and the night sweats have come back..still hanging in there but need a bit of encouragement x

    • donna30993 donna30993 luci11

      Thanks Luci,

      ​You're advise and support is helpine me get through these difficult days so much.  My husband doesn't have much sympathy/patience with me, not because he's a bad person, just because he doesn't understand as he is a very laid back, worry free person (the opposite to me)!! so I'm just glad I can speak to people on here that have been there or are going through the same thing.

      ​Donna xx

    • lookingonwards lookingonwards karen60759

      I can not remember but it was for sure longer than 5 weeks.. more like 12 weeks or more. Even now after about 9 months of being on them I still have a random blip day.. keep on with them though... one day you will just realise that you are not even thinking about the tablets and living life! Night sweats sound hormonal...

    • luci11 luci11 donna30993

      I understand what you are saying Donna. Not everyone understands what we are going through. Also for men as our partners it is frustrating because their natural tendency is to want to help and they feel powerless in this case and it is hard for them too...they always just want to give you solutions and don't understand that just patience or talking or being there is the help. I have also learned with my friends who I can talk to about this and who not...some people just have no capacity to understand, they think it is just a matter of having to make more effort to 'cheer up' or get busier not to think about the lows, and it is not so simple, and then I feel even more like a failure if I cannot take their advice on! So these forums are really helpful, to talk to people who go through the same and understand. I am grateful for it. smile

    • donna30993 donna30993 luci11

      Yes Luci I completely agree! unfortunately my husband and family don't understand and think I should "just pull myself together" but like I told them, if it was that simple nobody in the world would suffer from anxiety/depression.  Unless you've been through it, nobody understands and that's why this forum is such a help to me. xx

    • karen60759 karen60759 lookingonwards

      Hi lookingonwards, hope all is well, I just wanted to ask if you can remember getting palpitations/ tremor / slight ringing in the ears after you went up to 40mgs? I'm starting to notice this more as it's been really troublesome in the past week along with a crash in mood,been feeling nauseous all day as well, just seems at the moment I'm experiencing alternating good / bad weeks (I'm almost 7 weeks on 40mg now) and I'm getting worried out whether these are Prozac side effects or something else, could well be hormonal too as that can also cause these symptoms, respect your opinion having been through this too! Thanks

    • lookingonwards lookingonwards karen60759

      What age are you if I may ask?

      Ringing in the ears on occassion....for sure nausea.. and heart pulps... especially when trying to sleep! The alternating good and bad is very very normal!! I had a blippy day on Friday even... but it has come good.. I knew it was just some stress from work.

      Hormones are a huge part as well!

    • luci11 luci11 donna30993

      Hi Donna, how are you doing these days?

      I am 12 weeks now on 20mg and I have been quite well in the last few weeks, energy and enthusiasm coming back and anxiety only on some days a little but it is completely managable now.

      Luci

    • karen60759 karen60759 lookingonwards

      I'm 40 so hormones could well be the root of the problem for sure, especially when I recall that the times I wasn't ovulating due to pregnancy and breast feeding were when I felt the best! So I'm seeing a gynocologist this week to discuss the options, feeling a bit calmer today, slept well last night! even thou it's a rainy bank holiday and I've got 2 kids to entertain! Thanks for you reassurance, means a lot x

    • donna30993 donna30993 luci11

      Hi Luci,

      ​I got back from a 2 week holiday in Turkey last night.  I was not looking forward to it at all as I had been feeling so anxious and down, but I think it has done me the world of good and I feel much better.  Maybe its because the meds are starting to work, or maybe just the rest and change of scenery helped.  I still get anxiety in the mornings but not as severe.  My paranoia and OCD still has a way to go yet too, but I do think I have turned a corner and feeling much more confident.

      ​Thanks for thinking of me Luci.  I'm glad you are continuing to improve.....you have been so supportive to me throughout this awful time, and I am truly grateful.

      Donna xxx

    • leanne56602 leanne56602 luci11

      Hi just after advice on day 6 never had any side effects until now last night of day 5 had an immense headache so uncomfortable today on day 6 I feel low can feel increase in heart rate making me feel panicky x I am on fluoxetine 10mg for my pms I really hope this helps me I can’t take no more x

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