Has anyone taken L-Glutamine with Prednisone?
Posted , 16 users are following.
I'm so worried about my stomach and muscle wasting with the Prednisone for my PMR.
I've only seen one author write about it, but that was in 1994. I don't see any more recent studies.
Seems a lot of benefits from it from what she said, but...
I was was excited to read about Betaine for stomach healing, but it says corticoidsteroid users are at high risk, do NOT use.
I refuse to take PPI's for I hear they make one worse when the acid rebounds.
I'm so sad the Pred has messed up my stomach. My diet is restricted enough as is. I'm down to 6 mg, but still in pain, but refuse to go up. I'm not sure doctor's care if this messes up my stomach, I wonder if it will heal when all this is done!!!!! Or do they care? I have some relief by drinking aloe Vera juice before I eat and lieing on my stomach, but do not know if that is ok to do. Ugh.
0 likes, 66 replies
EileenH LayneTX
Posted
Am I remembering correctly - is it you whose doctor has you on a very restricted diet? If so - I think perhaps a different doctor who doesn't insist on a restricted diet for PMR might be a helpful step. There is no mainstream work that shows diet makes a difference in PMR apart from the individual things people find triggers their discomfort. Some people find too much sugar does it, others dairy but there is no one size fits all so it is unreasonable to tell a patient to stop eating a normal varied diet. There is some evidence that a low carb diet helps with reflux and that is easy to try out if you eat a normal diet.
Have you tried yoghourt? Quite a few people have found that helps. Taking your tablets in the middle of a meal is also a trick that seems to help. Multiple small meals also helps with reflux, eating too much at one go often leads to reflux.
Someone else has already suggested Zantac (ranitidine) rather than a PPI, similar effect with fewer side effects - and you probably need more than a couple of weeks to feel a difference. There is felt to be less rebound but the rebound only happens when you stop taking the tablets anyway and as has been said, tapering them off, as with pred, helps avoid the rebound.
And if you want to know about taking supplements alongside pred - always ask your pharmacist for advice.
Artdesign LayneTX
Posted
I was having stomache issues on pred too. I'm at 40mg a day. The doc told me to take over the counter Zegerid in the morning before I take my pred. It has worked great. I can take it at other times during the day too as needed.
Hope you feel better.
steve_1 LayneTX
Posted
When I told the doctor this he tore me off a strip for not seeing him about the reflux earlier.
About the doctors not caring about issues that treatment may cause or bring to light....It seems to me that in the US, as doctors only get paid when they treat you, some may be banking future work. They are in a far different situation to those in UK who get their money anyway.....Am I being cynical???or what???
LayneTX steve_1
Posted
karenjaninaz steve_1
Posted
i am on Medicare. Medicare pays Doctor for preventive tests: vaccines, colonoscopy, mammograms and a yearly "wellness exam"" which screens for diabetes, bloodpressure, some cancers etc. So must insurance under "Obamacare". The whole point is prevention and early detection. The patient has no copay for these. Doctor quality is variable all over the world. The primary I used for years blew me off when I suspected I had PMR; he said I had fibromyalgia and didn't even refer me to a rheumatologist. I am changing doctors.
steve_1 karenjaninaz
Posted
It's the one disease that I would wish on a doctor....then perhaps they wouldn't be quite so blind. Especialy the male variety.
artfingers LayneTX
Posted
maureen96014 LayneTX
Posted
Is Omeprazzole the same type of tablet as you are taking?
My doctor put me on them recently when taking Naproxen with prednisolone as he thought I had gout but turns out it is arthritis instead - On his advice I came off the Naproxen after two weeks but he said to carry on with the Omeprazole - he said it would help with my acid reflux - but as far as I know I dont think I have acid reflux - I have a very weird sensation in my oesophagus that does not burn but is like a round ball of air that sometime come ups to my throat and goes back down - it is more uncomfortable than painful and sometimes when I eat I can feel the food going down my oesophagus not all the time just occasionally - the sensation is a little like when you eat something that is too hot and it burns going down - but without the burning - if that makes sense.I also do not have any pains in my stomach but find that I am having to go to the loo more often, usually in the morning even before my breakfast and I am suffering a lot from wind - sorry to be so personal but dont know what to do as when I go to the doctors at the moment I feel they are just not listening - if you or anyone else out there can help with my symptoms or the omeprazole I would be really grateful to hear from you
faye______00403 maureen96014
Posted
wasn't especially alarmed. The fourth morning it woke me up
and decided I'd better check it out. After another (had one
in Sept along with other tests) EKG and looking over all my
tests doc told me it was esophageal spasms. She picked up
right away on the fact that it only happened when I was laying
down. Anyhow prescribed OTC Gaviscon chewables and
stronger strenght Prilosec than you can get OTC. Pretty sure
Prilosec is omeprazone and it's an antiacid designed to help
with hearburn and acid reflux which I've had for years. As to
the issue of flatulence....are you by any chance lactose
intolerant? Any kind of milk products will give you gas
pains and bloating....there is a small pill called Lactaid
that you take just before first bite of anything dairy and it
helps keep that unpleasant feeling away....I know, I know
another pill I think I could just about open my own
pharmacy......
EileenH maureen96014
Posted
Faye is quite correct - Prilosec is a brand name for omeprazole.
LayneTX EileenH
Posted
I had read it could heal the gut. Or make a gut barrier.
but this paper says basically there's not enough proof.
but she did say there should be no interaction with Prednisone.
I refuse PPI's because when you stop it causes influx of acid. Though as Eileen mentioned above perhaps if taper that might help.
Other acid reducers can have calcium on them, so doctor warned me of too much Calcium and said lower amount I take if I chose to take Tums.
Maureen, what you said describes me. Like a spasm in my esophagus, no pain, but so irritating. But as I said, even water bothers me.
oh, and exercise, I did some sit-ups and sure enough I got that awful feeling.
On the acid reflux forum they warn people of stomach or esophagus Cancer, so I'm just trying to NOT get that!!!
I already have Osterporosis now, so I will not take PPIs.
But today...I'm trying to pretend I'm OK!!!! It's sunny and gorgeous outside, though darn bees keep chasing me since I put on smell good lotion! Ha!
LayneTX
Posted
To Maureen asking about tablet.
EileenH LayneTX
Posted
maureen96014 EileenH
Posted
Thank you so much for your reply - I am so worried as I dont thibk I am having acid reflux I described my symptoms to the doctor and he just said I will give you omeprazole but I definitetly told him that I had no burning sensations - I think I am just going to stop taking the medication in view of the fact some PPI can cause cancer and when I see him in a few weeks time for my dexa scan results I will explain to him why I have stopped them
Thanks for your help as always
Take Care xx
maureen96014 LayneTX
Posted
Thanks so much for your reply
I have decided to stop taking the omeprazole until I see my doctor in a few weeks for my dexa scan result - I told him I had no burning sensations but described the "spasm" in my oesphagus and he just said I will gie you omeprazole!!
So frigtened of getting cancer so not taking it - have you explained the "spasm" to your GP did he say what it was by any chancde and whether it needed further investigation - I dont know if it is my imagination as I am really getting "worked up" about it but I feel I have a slight blockage at the back of my throat today but not sure if it just because I am getting so stressed with the doctor giving me so many different tablets I feel I am turning into a hypocondriac!!!!!!!
Oh well, heres hoping tomorrow is a better day
Hope you are having a good day#
Take Care xx
EileenH maureen96014
Posted
"However, in some people, small amounts of stomach juice can spill back into the upper throat (pharynx) affecting the back of the voice box (larynx) causing irritation and hoarseness. This is known as laryngo-pharyngeal reflux (LPR). It is often called 'silent reflux' because many people do not experience any of the classic symptoms of heartburn or indigestion.
LPR can occur during the day or night, even if a person hasn't eaten anything. Usually, however, LPR occurs at night.
The term reflux comes from a Greek word meaning 'backflow'. Normally, the things we eat and drink stay in the stomach to be digested and do not spill back up into the oesophagus. However, if the valve at the lower end of the oesophagus (the oesophageal sphincter) is weak or disco-ordinate reflux may occur.
What are the symptoms of LPR?
The most common symptoms of LPR are:
- A sensation of food sticking or a feeling of a lump in the throat
- A hoarse, tight or 'croaky' voice
- Frequent throat clearing
- Difficulty swallowing (especially tablets or solid foods)
- A sore, dry and sensitive throat
- Occasional unpleasant "acid" or "bilious" taste at the back of the mouth
- A feeling that too much mucus/phlegm is collecting in the throat
- Sudden coughing or choking spasms at night
- Chronic cough
- Excessive burping, particularly during the day
Heartburn
Some people with LPR also experience heartburn. Others rarely notice heartburn or never experience it at all (hence the term 'silent reflux'). This is because the material that refluxes (refluxate) does not stay in the oesophagus for long. As a result, the contents do not have enough time to irritate the oesophagus and cause heartburn.
However, if even small amounts of reflux come all the way up into the pharynx and larynx, other problems can occur. This is because the tissue lining the larynx and pharynx is more sensitive to injury and irritation from stomach juices than the lining of the oesophagus. Damage to the larynx from stomach refluxate will affect a person's voice and can sometimes affect their lungs and breathing."
What your GP should really be doing is not making an assumption but sending you to see an ENT (Ear Nose and Throat) specialist or a gastroenterologist who can examine your throat and gullet to see if there is any damage rather than just handing out a prescription for more tablets.
LayneTX EileenH
Posted
I'm convinced, silent reflux. I have managed to sleep with LOTS of pillows propping me up. I have awakened choking if I'm flat. We have allergy season coming and lots of rain, so that contributes to extra mucus. Noticed I'm clearing my throat more often now, but read on ther forum a guy's throat getting sore from that, so again, sipping water is helping.
Like Eileen said, I'm going to try many small meals, keep sipping water perhaps to keep throat clear, as I said, the aloe vera juice helps, though I now think I need to not drink it too close to Prednisone ingestion incase it's impeeding absorption.
Also, she mentioned taking Pred in middle of my breakfast verses after, that seems to be helping a bit too.
My Rayos is coming in mail, so maybe that will help, though who knows how long till my tummy and or esophagus heals. Will report if I get more relief.
oh, my ENT said to try childrens (gosh, moderator might nix this...I'll try to not say name brands) allergy liquid and antacid liquid mix. But the sugars got to me.
faye______00403 LayneTX
Posted
spasms.....I read somewhere that chewing gum will help keep
acid down but that wouldn't solve night problems....I too drink
aloe vera juice and do think that is helpful. The Gaviscon the
doc recommended is in chewable tablet form Chew up 3-4
swallow with a glad of water and she says creates a barrier
between stomach and esophagus....worth a try....
maureen96014 faye______00403
Posted
Take Care xx
maureen96014 EileenH
Posted
Have a good weekend xx
maureen96014 LayneTX
Posted
Thanks for all your help I am so grateful to you and Eileen - at least I know what might be happening to me now
Have a good weekend xx
LayneTX faye______00403
Posted
i forgot ENT gave me Carafate Suspension, but I remember it's so hard to take 1 hr before eating or 2-3 hours after, seems I'm always eating, ha. So today I set my alarm on my watch and just took it. Plus I think it has sugar in it so maybe I reacted to that before, ha, can't remember.
Thanks!
karenjaninaz faye______00403
Posted
Also, some chewing gums have sugar substitutes like sorbitol and maltitol. This can also be a "wind maker".
As an aside, got bad wind from a prescription iron preparation whereas an otc was better. (it's a wonder I haven't floated into space(. I got clearance from my rheumatologist to take it.
My anemia came with PMR and I thing taking purified Curcumin, recommended by my pain doc before we knew I just didn't have bursitis,chelated my iron. I have the scientific paper reference for this. No bleeding areas found in my digestive tract.
LayneTX karenjaninaz
Posted
Thanks for your input!
karenjaninaz LayneTX
Posted
This is the article from a hematology journal regarding Curcumin.
My pain doc was not aware of this when he suggested I try it.
Mrs_CJ LayneTX
Posted
The Cleveland Clinic site has information about sleep position. Apparently it's best to sleep on your left side as much as you can. Can't remember the reason but this is a reputable medical site and it's easy to try.
LayneTX Mrs_CJ
Posted
yesterday I saw a show on TV that said lay on left side because stomach is lower than esophagus and acid less likely to go up tube. Right side is higher so acid can.
However left side is hard for people with heart issues.