Has anyone taken L-Glutamine with Prednisone?

I went through having no taste buds for months.  

Yes, been tested for Sjogrens, and all...

GI doctor offered no resolution. 

I've heard one can have too much acid or NOT enough! But doctors don't seem to want to find out. 

I tried PPI for 14 days, no change.

im sick of drugs!

I had another endoscopy this year and it showed a tiny bit of inflammation, no hiatal hernia or acid reflux. I have been taking Prednizone for 2 years.

I always wondered if the inflammation and pain I was having was the PMR. I rarely have heartburn anymore. Just a thought.

I don't burp acid, I don't taste acid, I don't cough, it doesn't bother me at night, just 10-20 minutes after swallowing liquid or foods.  If I eat larger meal then yeah it waits longer before the odd gurgle in my throat/esophagus. 

If I drink wine then next day I can't taste it and have raw tongue. But sometimes the wine quiets the feeling, but one doctor said that was just that I didn't care, ha. 

Also lately crave sugar!!! So the L-glutamine stops that craving too, but I'll go ask pharmacist if I can take it. I think the sugar craving is my adrenals and maybe thyroid, I recently switched to Armour. 

buy plant based empty capsules fairly cheap.  Would it be better

for all of us to put the pred inside one of those and swallow it.

It would at least get past esophagus before starting to dissolve.

I also take Fossamax (thanks to our old friend pred) and

wonder about putting that into empty capsule...

It is perhaps something to run by a pharmacist - some drugs are better absorbed in the stomach, though that may be due to the pH of the environment and I can only assume that if you are on a PPI the stomach contents won't be as acidic as normal so does that still apply? It isn't the oesophagus per se that is the problem with pred - it is the risk of gastric irritation and, eventually, gastric bleeding. Some experts think that even enteric coated versions won't avoid that - they believe it is the level in the blood that leads to the problem. But the jury is probably still out on that.

For Fosamax you would think that, given the problems there were with patients not taking it properly, that they would have put it into a gastric acid-resistant coating if it were not a problem. Or would that mess up their profits?

And do bear in mind that whatever the capsules are made of, for some people THAT may give rise to problems, especially if there is colouring in the material.

I've always taken it with 3 egg whites and often include avacados, spinach and bell peppers (though I've recently stopped the bells and night shades to see if those give me issue), lately adding lots of mushrooms.  No never an empty stomach. 

However - you can still have reflux even with a PPI where the acid production is prevented. And yes, one thing to try to help is eating half your meal, then taking the pred and then finishing the meal. 

I assumed that would break coating... Or perhaps it's not just a coating but the entire makeup of the pill that slows it down? 

I asked him if there were enteric coated gel caps available and he said he didn't know.

I asked him if I could find enteric coated gel caps and if I put my pred in them, would it effect my pred's effectivenss if it couldn't dissolve in my stomach.  He didn't know.

I know that Rayos is being discussed as a solution, but it is not available to me here in British Columbia Canada.....which means it's probably not available in this country.  Very odd, as it's been in the USA for awhile.

Thank you for the reminder that it is known under other names. I think Medrol is another coated one in Europe. 

Medrol in Europe (or anywhere else) isn't a coated version - it is plain white tablets of a different corticosteroid, methyl prednisolone, prednisolone with a methyl group added to the structure. 

A study in Crohns disease showed there may be improved management of the intestinal inflammation using enteric coated pred - which is more likely to be absorbed in the region affected, rather than in the stomach. If enteric coated pred is absorbed somewhere in the gut, so too will pred from inside acid-resistant capsules. The peak blood level may be lower or peak more slowly (i.e. be spread over a much longer time) but you adjust the dose to get the level of effect you need in PMR anyway. If your doctor lets you at least.