Has anyone tried Constella (linaclotide)

I got this medication from my doctor 2 weeks ago and have been taking it as instructed for 10 days. I'm not sure how long it takes to start working but as yet no relief or side effects yet.

Would be interested to know how you get on. I live in Spain most of the time and it is not available here yet. I was wondering if i can get it when i come back to UK for a short visit. Is it easy to get from the doctor, or is it not being prescribed readily? I assume it is not available from the pharmacy.

I just tried it for 5 days and it gave me very bad diarrhea within an hour of taking it with no easing of

symptoms.

Thanks for that Amanda, not sure what I should do then. Not enough people seem to have tried it to get to make an informed decision.

I will say that everything I have ever tried has done the same . I tried Zelnorm years ago and the results were the

same. I am thinking of going back to the homeopathic Dr. Medications don't seem to work for me. Also , my

regular Dr. told me I would see results in 2-3 days if it was going to work so who ever has taken it for 10 with no

results should take note.

Try Total Candida Defence, working for me after one week! Also an IBS sufferer. I have also cut out Gluten from my diet which has also helped. Bread seemed to be the worst culprit for bloating!

Thanks for that. Where do you get Total Candida Defence, is it chemist or health food shop? Have tried other things for Candida before as like you bread i think is a problem. I think its the yeast though rather than the gluten as gluten blood test came back negative.

hi i have been put on this new tablet,been on it a week,

Hi Margaret,

I got prescribed this in January. Tbh it's very sporadic with me; 1 tablet sometimes unblocks me, sometimes it does nothing, sometimes it gives me horrendous diahorrea. I wud do it at a weekend if you don't have a busy one, to allow yourself to be housebound. If you take 2 and constipation is bad it works wonders but will also make u housebound for a day. Xx

Have just started on Constella from being on Prucalopride (Reslor) before, Over the past year or so I had put on 1 1/2 stone adn could not shif it no matter what and was suffering extreme fatigue to the point of exhaustion.  My GP found nothing wrong (and was not much help either).  After a lot of searching on the internet I came across a forum where women had experiences similar to mine and were on Prucalopride.  I have now stopped this and am taking Constella (another internet search and not a GP suggestion!!).  I suffer from terrible constipation due to IBS, have completely changed my diet but cannot cope without something to help my bowels move.  Can anyone tell me their experiences with Constella?  I am so scared of gaining more weight and need to get rid of this fatigue (hopefully this will stop soon once the prucalopride effects are out of my system).  Desperately needing help as cannot go on with wieght gain and fatigue.  Would like views on how well Constella works and any side effects.

I have been on Constella for three months now and it definitively works.Yes , the 3-4 hours after taking a dose is a bit annoying (gurgling & the loo) but compare of my chronic constipation, cramps & bloathing, I find it's a little price to pay from the burden of pain I used to suffer.

I am still in the trial and error mode as when to take Constella. I tried to avoid to get houseriden by trying taking it just before bed so I could go to the loo early in the am but no such luck there since it woke me up in the middle of the night with the dreaded few hours of running to the loo...oh well back to the am regime.

Overall, Constella does it's job and enjoying life once again...Thanks Constella!!

I have tried, and taken , Constella for over a year. It has worked very well for me. Less straining, and more frequent BM'S. One great thing about this drug is that it comes in 2 different doses, so if the lower dose dosen't work, you can have your dose bumped up. On the flip side, this drug can work so well, you may need to move to the lower dose once you're more regular. This drug is a life saver!

The downside is that it is very expensive (at least here in Canada), and some plans don't cover it.