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How long can it take for the pain to return after stopping Methotrexate?

Posted , 13 users are following.

SharonAnneH
SharonAnneH

Last week my consultant stopped the Methotrexate I was taking. I was on 25mg a week every Thursday. I have not taken any for about 11 days now. I am in more pain than usual today and I would like to know if the drug comes out of your system that fast or am I just having a bad pain day? 

0 likes, 23 replies

23 Replies

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  • Ever_hopeful
    Ever_hopeful SharonAnneH

    Posted

    I found your question interesting. I don't know the answer but when I've had to come off MTX (for the same reason) I have managed a fortnight before my RA pain kicks in and a month before I feel that I'm back to square one. For all its side effects I've found Methotrexate to be a wonder drug - giving me my life back. Good luck with everything.

  • sandy12801
    sandy12801 SharonAnneH

    Posted

    Hi everyone,I'm new to this page and was very interested in this discussion I have been on Methotrexate for four years and was recently taken off a month ago due to my liver function tests not being so good! I am in terrible pain and am really concerned that I'll go back to where I was and a quite nervous,any advice greatly appreciated smile I can relate to what you are saying SharonAnnH

  • leslie19171
    leslie19171 SharonAnneH

    Posted

    i am leslie and new to this and i use to take 8 tabs a week i stopped taking a couple weeks ago and i am in agony but will not back on them because i thought they was not working and yes they do come out of your body quiet quickly
  • mrsmop
    mrsmop SharonAnneH

    Posted

    I am not certain when this was originally posted Leslie but I had to stop taking the MTX altogether because of the pains it was causing in my joints. It also caused a totally addled brain!

    I forget when I actually stopped it but I have been taking Mycophenolate Mofetil since about April of 2015.  It is a much pleasanter drug to take but of course, it too has its own side effects.  I have had to drop the dose because of side effects but am still taking it at the moment.

    I have an auto immune skin disease called Mucous Membrane Pemphigoid.

     

    • leslie19171
      leslie19171 mrsmop

      Posted

      abòut five minites never good at spelling have ra for about 20years then they started me on metatrexate i thought it was not doing anything after 4 months so came of now in agony but not going back on it

    • mrsmop
      mrsmop leslie19171

      Posted

      It does take at least 12 weeks to start to have any effect so maybe it was doing something.

      Why did you stop taking it?  You can write MTX, it is short for Methotrexate!!

      Did you take the Folic acid too?  You have to take it on a different day from the MTX.

  • leslie19171
    leslie19171 SharonAnneH

    Posted

    the pain will get worse and you will get more pain than before i no because i stopped taking it and if i can i will go back on it to stop the pain also how many tablets r you week is that 2.5 mg a week

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