Lansoprazole to Ranitidine

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Hello everyone, I'm new to the forum I hope I can get a bit of reassurance that I'm not the only one who feels all these strange symptoms!

I'm a 21 year old otherwise healthy female and never had any medical problems until now.

I went to the doctor this summer as I'd started feeling really sick after eating sometimes and often felt like I had liquid stuck at the bottom of my throat. However wasn't sure if it was acid reflux as it didn't often feel like it was burning? He gave me lansoprazole 30 once a day for about 4 months and it worked to keep acid and feeling sick to a minimum but I didn't feel 100%. I went back to the doctor a few months later as the symptoms reappeared when the tablets stopped so he sent me for a gastroscopy which came back all clear. I've also had blood tests and test for H-Pylori all which came back clear. The gastrologist said it didn't sound like acid reflux because there was no burning and no soreness in my throat? Although he said the symptoms I was experienced did sound like reflux. Anyway he basically couldn't work out what was wrong so put me back on the lansoprazole.

I went to the doc yesterday to get some more and she suggested putting me on ranitidine instead to see if it was any better. I started them today (one tablet twice a day) and have felt some strange symptoms! Earlier my tongue and lips was burning and my arms aching and hands tingling!? Are these common side effects from ranitidine? I saw some earlier posters said they'd had a bit of nausea which I don't seem to have experienced.

Could all this (acid reflux, stomach aches, burning tongue etc) be linked to stress and/or anxiety?

Thanks for reading

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  • Posted

    The burning tongue is certainly linked to these types of medications, when I had it my tongue was very noticeably bright red, my GP gave me an oral thrush medication Nystan (Nystatin) and it cleared up, I haven't suffered from the burning / red tongue since (I'm still taking Omeprazole) smile
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  • Posted

    [quote:3bc684d244=\"Dr_Spock\"]The burning tongue is certainly linked to these types of medications, when I had it my tongue was very noticeably bright red, my GP gave me an oral thrush medication Nystan (Nystatin) and it cleared up, I haven't suffered from the burning / red tongue since (I'm still taking Omeprazole) smile[/quote:3bc684d244]

    Thanks for the reply, the burning sensation episodes seem to come and go, it happens about once a week. Felt ok the first day taking ranitidine however yesterday I felt horrible all day and even had to stop the car when I went out because I felt so sick! Do you know whether the nausea from taking ranitidine goes after a few days of been on them? I don't want many more days feeling like that! Woken up this morning feeling like I'm hungover even though I didn't drink last night!?

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  • Posted

    mmm..interesting i went to the doc as i had been getting sharp pain in my gullet when eating, and feeling like id not swollowed my food down properly...after years of heartburn. he gave me omeprazole and wow did they help the feelings but i also felt very unwell on them..so he put me on zantac and at first they seemed to help but after about a week the symptoms are back...but i now realise the burning sensation on the tip of my tongue is possibly connected to zantac?? thanks for posting
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  • Posted

    i went to the doctor as i have been feeling sick for about 4 weeks now it seems to be at the back of my throat and my stomach my problem is that ever since i was young, if i am sick i faint, i am so on edge that i am now getting panic attacks  i have been prescribed Ranitidine but i was wondering if it was correct as it all seems to mention acid reflux problems but as you suffer sickness and have been given Ranitidine as well it makes me feel a little bit better i hope i don`t get any of the problems that have been mentioned
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    • Posted

      Hi Janet 320, I saw your post and I feel very much the same way as you. I have phoiba of being sick and I'm worried that taking these tablets will make me ill. It's been 2 months since your post and I would really like to know how you got on with the tablets thanks.
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  • Posted

    Hi All, just found this thread after a Google search.

    Right, briefly.

    About 20 yrs ago I was found after having long bouts of reflux to have a very minor case of Barrets Oesohpagitis so was put on oemprazole, which did not work (continued reflux, nauseau etc) so I was put on Lansoprazole and as so many have said, after day 1 my life changed.

    The relux halted totally, and to test just how good this stuff was I went out with my mates, drank quite a few beers and had an Idian meal, no problems whatsosevr, apart from the hangover.

    I kept my diet and lifestyle as clean as most guys do with the ocassional 'off the rails' sessions over the years.

    Lanzoprazole just kept on working.

    Initially, once or twice, I noticed my stools werer very light in colour, almost white, but this was only on two rare ocassions, normally, my bowel habits are very regular with Lansoprazole.

    In ths following 3 years I had three endoscope procedures with biopsies, all clear, no dysplasia etc, but was told by the consultant to stay on this Lanzoprazole forever, basically.

    SO I have.

    Over the years I have had a day or two off them, either because I messed up my perscription renewals or just wanted a day off them, and I can say that within a day or two of not taking them, my hormones seem to peak, I have a bigger appetite and if I don't eat more food I get hypoglycemic very quickly.

    My voice also drops quite noticeable (I'm 47 now but this has been the case over the 20 yrs) and my stools are more substantial.

    I firmly blieve that due to the action of PPI's like this reducing the amount of stomach acid that it has a follow-on effect on the body's other system such as hormones etc.

    Side effects; I've never really had any I can call to mind other than very rare dizziness.

    Now then; today I went back tot he GP as my meds were up for review, and lo and behold the GP wants me to try Ranitidine as he says there is anecdotal evidence (not proven) that Lansoprazole is linked to osteo-arthritis, which runs in my family and I have recently been told I have mild arthritis in my loweer spine.

    Needless to say, I'm a bit loathe to swap from Lansoprazole to anything else mainloy as I don;t want a life of heartburn, reflux, agony etc again.

    I DO know there may be some discomfort for a day or two during the swapover.

    Anyway, just figured I'd pipe in here and keep this thread updated; basically I am a tad suspicious this is a cost saving excercise at the potential risk to my health given the state the NHS is in these days etc.

    We'll see.

    Anyone else heard about the link to osteo-arthritis and Lansop?

     

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    • Posted

      Yes, my doctor told me the same thing that lansoprazole can link to arthritis so she changed it and gave me ranitidine. I am taking it twice a day but now I feel bloated stomach and get very uncomfortable feelings. Thinking to go back to doctor. Does any one else who takes ranitidine feel the same way?
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    • Posted

      Hello, found this thread through Google. Made the switch from omeprazole to ranitidine, seemed to work okay for a couple weeks but I too experience stomach discomfort and bloating. Also I experience fatigue/body weakness, I don't know if anyone has ever felt that from the meds but it scares the crap out of me...
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  • Posted

    Hi Just Fix Me, ok firstly are you in the UK?

    I am, and I strongly suspect this changing from Lansoprazole, Oemprazole etc to Ranitidine is simply a cost saving exercise by the NHS (understandably).

    Ranitidine is simply Zantac, an over the counter brand kind of similar to Gaviscon and the other stuff, made to deal with occassional reflux.indigestion after a heavy meal.

    So, firstly, and this is only a suggestion from a patient same as you, if the Lansoprazole worked for you better than anything else then I would tell the GP I want to go back on it, simple as that.

    My own GP suggested Ranitidine but also renewed my Lansoprazole on my 'account' and said if it didn;t workj or agree with me that I could go ahead and re-order the Lansoprazole, and htat is just what I did without trying the Ranitidine.

    There is no way I am going back to the misery I had pre-Lansoprazole.

    Should I give the Ranitidine a go and see?

    Maybe, but this is my health and I do no see why I should screw up my day to day life just for the sake of penny pinching; I have lived and worked in the UK all my life and so am entitled to the best care available; the financial state of the NHS is not going to sway me into lowering the quality of my life or risk enticing a more serious condition caused by constant, long term reflux.

    Regarding the tingling and buring sensations reported by Ranitidine users, I can't comment as I never have (nor ever ever will) used it.

    The up side to this is you have had all the blood and visual and biopsy tests done that normally reveal conditions linked with reflux (GERD), and they all came back clear.

    Even if you were worried about a tumour or whatever, I am pretty sure the endoscope (camera) would have enabled the specialist to see anything abnormal down there, which they didn;t.

    So perhaps a lifestyle change is what you need?

    Looser clothing around the abdomen, maybe there is a food type that causes this sickness and 'liquid' sensation?

    I never have been able to deal with pork, gamon etc, it has always stuck in my gut and caused me to feel unwell, so maybe some of the foods you are eating have an ingredient or component in them that cause your problems such as an oil, or colourant or preservative?

    If this offends, sorry, but some peoples' oral hygene is not what it should be, and bacteria can build up quite quick at the back of the throat, particularly if you smoke and don;t drink enough clear liquid in the day, and don;t clean teeth often enough in the day.

    Perhaps stress is an issue too.

    Only you can say really, as no one on here can see your day to day, hour to hour routine or lifestyle.

    At least you can pop on here and discuss stuff with people who have similar experiences and can relate to your worries and discomfort.

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    • Posted

      Just read these post i was taking 30mg lansoprazole but found it gave me stomach upset i came off it and i was fine but i have anxiety and get this gas feeling in middle area of stomach well last week doctor gave me lansoprazole again and i got stomach upset so now they gave me RANITIDINE liquid not tried it yet
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    • Posted

      Hi, I refuse to take PPI's prescribed after camera found Reflux, HH, Esophagitis.  I know once you are on, you are stuck on them and the side effects of taking long term are not good.  I would only take them if I had Barretts, then I would have to.

      I take 150mg Zantac am and pm on prescription which does me fine.  Along with that I take Mastic Gum at night and something else which every time I mention it gets moderated, though I do not understand why.

      I can run on this and be careful of citrus and spice and meat and I rock along well.  I relapse because I feel well and then cheat and backwards I go.

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    • Posted

      Since your post? was the most recent, and had something to do with what I have been going through I decided to share my story. I am 31 years old have had Crohn's disease since I was 24 and also diagnosed with a hiatal hernia at the same time. I was immediately put on omeprazole 40 mg qd. This cured my chronic heartburn on day one. This has been my everyday medication for the past eight years and haven't really encountered anything strange up until 10 months ago. Heart palpitations, shortness of breath, anxiety, feeling like I am going to pass out. I am a nurse and have tried to get every test I know done. Thyroid, carbon dioxide, pulmonary, cardiac, neurologic, embolisms, another auto immune disease, pretty much everything under the sun and everything came back negative. Due to my complaints, all doctors pushed it off as anxiety, put me on anti depressants, and as soon as I took one, full blown panic attack. I was beginning to think maybe it is anxiety since everything else checked out. But I can tell the difference between anxiety and breathing issues. So I became my own advocate because every hospital, urgent Care, GI, PCP all said there's nothing wrong. I began to look at what I take daily. Humira, methotrexate, folic acid, and omeprazole every day. I looked up long term side effects of omeprazole, and low and behold, everything I've been complaining about other people have too. It even went so far that a doctor told me to get a breast reduction because I have a large chest but I've had them for 17 years with no issues and I am not overweight. If you Google can omeprazole cause breathing problems you will see the posts that I did and it will make you think twice about taking any PPI for a long period of time. Once I confirmed what I thought I immediately stopped the omeprazole. I am currently on day 3 without taking it and I'll tell you I have noticed a difference in my deep breaths and far. On my thirty minute ride to work I would have to catch my breath at least 25-30 times. I truly felt? like I couldn't catch my breath and this was constant for ten months. Even at home I would have deep breathing issues just relaxing watching TV. Some people said to taper off, I refuse to put that stuff back in my body after reading what I read! I am down to maybe 5-7 breaths but can get it on the first try driving, definitely subsided when I am home and work. But I will tell you this. When your body becomes dependant on a medication for so long there are withdrawal symptoms. First night, couldn't sleep, anxiety, arms were tingling and went numb. Second night my legs went numb, cold body temperature, some anxiety, heart palpitations. Third night, I threw up, feel like I have a fever, headache, and muscle aches everywhere. Heartburn is horrible but I would rather have heartburn then feeling like I couldn't breathe and no one would do the research to see what could be causing it. I tried to take ranitidine to help with the heartburn, doesn't work and I believe that's making me nauseous. I go for a colonendoscopy the 25 of May and will be getting my hernia removed after the test so I don't have to go through this anymore. I advise anyone who was feeling any one of these symptoms to speak up for yourself and know that what you are feeling is REAL. I live in Vegas and these "doctors" are sub par to any providers I've ever encountered. I am a number here and not a patient, and I'm a NURSE!!! Dermatology though, so the providers I work with I can say do care about patients and they suggested to look at my meds and see what could be causing these issues after everything else checked out negative. The road to normalcy is ahead and it will be hard to go through the heartburn and symptoms of withdrawal, but to breathe like normal, not have "anxiety" feelings, putting myself in the ER because I thought I was going to pass out will all be worth it. I am in the medical field to make a difference and if I can help one person my mission is accomplished. I hope this helps anyone going through similar situations and if anyone has anything to comment about this and if they went through something similar I would appreciate it.

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    • Posted

      Forget to mention taking PPI'S absorb all of your nutrients and vitamins especially B-12 which controls your Central nervous system which can cause anxiety and heart palpitations.

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    • Posted

      Hope you are feeling better. This is my case: I had acid reflux and anemia had to take Omeprazol for a very bad episode of stomach burnig for 6 months aprox.  and got a serious b12 deficiency with neurological and phychiatric manifestations. Such as shortness of breath, anxiety, depression, fatigue, numness in m right leg and foot, back pain and burning, burning in my knees, elbows, profuse sweating, pins and needles in my legs, balance loss, and stiffness. I was diagnosed over 5 months later. 3 Neurologists said I had nothing. My primary doctor missed it, and never tested my b12. After doctors told me I had anxiety and had seen a Phychiatrist that assured me that I had no psychological problems but he thought it was caused by a neurological problem. Over 5 months I got worse and could barely walk or see clearly. I found an article in b12d . org and in youtube about b12 deficiency and got my b12 tested. It was 200 even if I had been suplementing for a month at that point. I received b12 injections for a year and the neurologist told me to never stop taking b12. I have never fully recovered, but I am walking fine and have no anxiety or depression since then. 4 years ago. I take now 2500 b12 a day and 1000 vitamin D (was also low at one point). Even if 200 is b12 low limit, it was extremely low and some countries have higher thresholds. I keep my b12 above 1500. I take Ranitidine now and I am aware that the deficiency can come back. So I take my b12 religiously and have a b12 shot every other month. I still have leg weakness and neuropathic pain in my legs.
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    • Posted

      Your story is EXACTLY like mine, even down to the latest thing being my doctor trying to refer me to a psychiatrist. I had all the same symptoms as you, and in January this year I was rushed into hospital by the paramedics as they thought I was having a stroke. The dizziness, shortness of breath and weak feeling in the limbs all pointed to this, but having been off the tablets (Pantoprazole, 40mg p/d) for 4 months, all I am left with is the shortness of breath you describe. Yesterday I was referred to a cardiologist, although I do think it's going to waste his time, as I am pretty sure this is still the remnants of the PPI tablets.  Yesterday I was reading an online newspaper and came across which makes interesting reading.  The similarities between us makes me think there must be hundreds, if not thousands, of people who must be going through the same thing as us, and aren't aware of why it's happening.  As you say, if this reaches one person who it helps after reading, it's been worth the typing time!!

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