Losartan over-treatment

Posted , 5 users are following.

This discussion has been locked due to a period of inactivity. Start a new discussion

I have been on this medication for ten years, firstly 50mgs, (tolerable), and a couple of weeks ago my gp upped it to 100 mgs. I have chronic fatigue resulting from a brain haem several years ago, and this amount is intolerable and worsening my symptoms; fatigue, poor concentration, intense itch upper torso, arrhythmias. I returned to see a different gp who suggested stopping for a couple of weeks to see how symptoms improved. After seven days I felt a new lease of life and elated. However, last night I thought I would take a peak at my BP and it was 177/99, so obviously concerned, I took a tablet last night. BP this morning 135/85 - very effective but now I'm a zombie!! 

0 likes, 24 replies

Report

24 Replies

Next
  • Posted

    HI Jane6...I'm sorry to learn you're feeling like a zombie...all because of medication.

    I'm certianly not a doctor, but anything I've read about medications specifically says that doubling medication usually only serves to increase side effects. 

    You took a peak at your bp & iw was 177/99...were you stressed at the time...did you take the reading within 30min of eating, exercising, showering etc. This can make a big difference. Also if you wait about 20min after taking that reading..there may have been a drop in the numbers. Here's a suggestion you might try...you were taking 50mgs & found that tolerable, but the 100mgs tipped the scales to the other side. Why not ask your doctor about taking something in the middle, say 75mgs. 

    You also said you were on the 100mg dose for a couple of weeks...just how long? Sometimes it can take a little longer for your body to adjust.

    Please let us know how you get on with this.

    Report
  • Posted

    I have had reactions to just about every drug I have tried so now, when it is suggested a dose is doubled by taking two tablets each time I usually cut the second tablet in half so the effect of the increase is reduced. This is pretty much Mike is suggesting but these days I am wary of dramatic increases in a drug. If you find you are reacting to an increased dose it often helps to lie down and elevate your legs by putting your feet up on a chair. Everyone is different and everyone reacts differently to drugs, finding the best solution is really a matter of trial and error so do not despair, there will be a solution that is best for you.
    Report
    • Posted

      Thank you Colin, that's helpful advice with the chair. I have a fat knee (leakage of synovial fluid) from carrying something very heavy last week. I consider myself fit and do a lot of dog walks, but have needed to slow down this week and rest, but not with my feet up...will give it a go!
      Report
  • Posted

    I have been taking 100 milligrams for 2 weeks now and so far no side effects my blood pressure ranges from 135 over 85 to sometimes 165 over 90
    Report
    • Posted

      jerry53202...you said your bp ranges from 135/85 to 165/90...when does this spike occur? If your at all stressed, it isn't a good idea to take a bp reading, as the reading will very likely be higher than normal.

      If it's bouncing up/down over a few weeks, especially after taking the increased dosage, I'd be very inclined to consult with the doctor.

      Report
    • Posted

      thanks Mike I do have an appointment next week to see my doctor. My blood pressure is usually high in the morning and lower in the afternoon
      Report
    • Posted

      Thanks Jerry, that's useful to know. I cannot tell whether my skin itch is caused by the increase or something else as when I came off the tablets I still had the itch. But one things sure - fuzzy head, terrible fatigue in the mornings, lack of concentration and arrhythmias have been unbearable. Just having that reprieve from taking them for a week made me come alive. When I was first put on losartan I was unconscious in the hospital recovering from a brain haem so I put all symptoms down to that. But just missing a week of drugs and feeling so much better for it, makes me wary of returning to them. Incredible to think how a tiny pill can have such a huge effect on everything!
      Report
  • Posted

    Well my gp thinks I should swap losartan for amlidopine 10 mgs. She assures me there won't be side effects. I'm nervous after being used to losartan for ten years, albeit the increase to 100 mgs last week which did me in. There doesn't appear to be any positive praise for this medication...having read the forum here, so not confident. I may decide to cut the losartan in half and implement a healthier lifestyle. Any advice?
    Report
    • Posted

      jane6...I'd never go against what a doctor suggests, but I don't see how she can assure you there won't be any side effects with the Amlodipine!!!!!! How can she accurately say such a thing!!???  Everyone is different, but as you know there are multiple complaints about Amlodipine in this forum. I for one hate the drug, but will be seeing my doctor very shortly to discuss coming off it because we feel it could very well be the cause of my burning feet/legs. Ive put up with this for a year now..enough is enough. 

      Why not ask your Pharmacist about weaning off the Losartan instead of cold turkey. Perhaps you don't have to wean off. If my information is correct, I believe Losartan is an ARB..& Amlodipine is a CCB (Calcium Channel Blocker). If this is the case, you can take both medicines at the same time, but I'd certainly consult the doctor before doing such a thing. 

      Please get back to us with anything you may need help with.What's why we're here!!

      Report
    • Posted

      Sorry Mike, I didn't see your reply until now. Thank you. I'm sorry to hear about your side effects with Amlodipine. I'm currently reading all about it on the forum, and don't like what I'm hearing. I think I'll speak to our local pharmacist for advice. It was another gp at my practice who recommended the cold turkey approach so I did that. He said to return in 2 weeks. After almost a week had passed, my BP suddenly spiked to 177/96, and I thought "enough's enough" what am doing? Took one of my 100 mgs tablets and knocked myself out!

      I am not going to even attempt to take my Amlodipine as I'm a fragile creature at the best of times. I am going to chill, take a 50 mg losartan tablet and Monday morning make an urgent appointment to see a different doctor at the practice. 

      Has anyone out there had a good result from taking BP medication? If so, what are you on?

      Report
    • Posted

      The doctor may have told you it was ok to go cold turkey...but when you did that, I'm assuming you didn't have other bp meds to take?? By going a week without any bp medication at all, I'm not at all surprised your bp spiked to 177/96...you obviously rebounded. On the other hand, when I read over your comment once more, do I assume correctly you were to come off the Losartan, THEN take the Amlodipine? If this is correct, then if you did follow the gp's instructions, you wouldn't have been left without taking any bp meds. You see Jane, you can't simply quit taking bp meds, i.e. if you were taking Amlodipine only, then you stopped...the bp would spike..same goes for the Losartan. Please let me know if I'm on the right track here.
      Report
    • Posted

      Hi Mike, the first gp (we have 12 to choose from at my practice) suggested I come off losartan due to my intense itch to assess if it was losartan responsible. I questioned his wisdom as I was worried my BP would elevate sharply - which is why I had a brain haem in the first place. He answered that a lot of the population walk about with high blood pressure completely unawares, and that I would be fine. Odd I know, especially in light of my brain bleed (several years ago now.) He told me to return in two weeks. I monitored my BP closely during that time, and when it suddenly spiked one evening, decided it best to call my usual gp, who suggested I start new meds - Amlodipine 10 mgs after hearing about my symptoms. I'm holding off taking these, instead I'm resuming losartan 50 mgs - the itch I'll just have to put up with.
      Report
    • Posted

      We delete content if it doesn’t meet the requirements in our Terms & Conditions.

Join this discussion or start a new one?

New discussion

Report as inappropriate

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up