Losing Weight Coming Off Mirtazapine

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Has anyone else had a problem with weight loss when stopping Mirtazapine? I don't have an appetite, and feel sick at the stomach, and have lost 10 pounds. I am beginning to worry that it may be something else going on.

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  • Posted

    Just about everybody on this forum lost weight after stopping mirt, don't worry. Try to eat despite not feeling like it. That was my problem too as I'm naturally slim and didn't want lose weight and I had to remember to eat but still lost several pounds.
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  • Edited

    Did you come off slowly or fast? Either way, a lot of people have withdrawal symptoms that can last a pretty long time. Easier doing a very slow withdrawal, though. I have tried twice and had to go back on.

    How long have you been off? What was your dosage?

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    • Posted

      I hope you get through it fast, David. It's pretty brutal just stopping. Sounds like you already know that. I would go back on and do a taper of dropping one dose a week, then 2, etc. and do it as slow as you want. In other words, if you need to take several weeks at just one dropped dose, then do so. Would be much easier on you. Just a suggestion. Some folks decide to ride it out, and for some, it gets better faster, and others, way slower. I wish you luck. Truly.confused
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    • Edited

      Kathy, I am miserable. The weight loss has me friegntened that it might be something else that is serious. I had a physical in December, and was in the ER last week, but all tests were normal. Since I am 3 weeks since my last dose, I would rather tough it out, as long as there isn't something else causing my digestive issues. I slept OK last night, but when I stepped on the scales this morning, I had lost a couple more pounds. I feel generally sick, weak, and fatigued. No appetite. I have a reasonable acute case of IBS that I have always had, which makes things worse. I have had, in the past, every gastrointestinal test there is, some of them several times, and they have all been normal. No family history of colon or stomach cancer. I just hope to get better soon. The most that I have weighed over the last several years is 215, I weighed 190 this morning. I am afraid (anxiety). Thanks for your interest. I would really rather never take another Mirtazapine.
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    • Posted

      I totally understand, David. Like I said, tried twice. I am not too proud to go back on it and try again later. The slow taper is safer and better for you. No one can tell you how long you will be in this misery with the sudden stop. But I hope it's not long for you.
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    • Edited

      Hi David, I'll pray for you and everyone else suffering WD from Mirt.                  About the weight David I was like you on 45mg now down to 7.5, and as you know suffering badly with servere IBS,I to have lost as we say in the UK a stone,but I can't say I've lost my appetite .  If your not eating you will not only loose weight,but you'll loose vitamins that will make you miserable.  I had a word with my Pharmasist and he said WD from Mirt best to top up on vit D it does help a little.   It's also said if you've dropped down never go back up.          I'll pray for you tonight x
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    • Edited

      Hi Kal and Kathy.  I started on Mirt at 30 mg. then 15mg. Then 7.5mg and last 3.75 mg. I have stopped now.  Been off 3 days.  I am getting these withdrawals.  Sweats at night...sleep not good...tremors...some dizziness

      palpitations but they are not as bad as when I was on Mirt.  Stay away from this med. Very bad stuff!!  Hope this helps.  

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    • Edited

      I gained weight on mirtazapine and lost a pound a day when I stopped(Yes, just stopped) taking 30 mg a day.

      You are fine. It's withdrawal paired with the loss of the fat MASS gained from the mirtazapine. I'm fat with it and miserable without it

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    • Posted

      Again, My doctor was alarmed by my 20 lb gain in 6 weeks and said, just stop. I lost 10 lbs of the fat I gained in spite of my usual healthy diet and exercise in 10 days. Hallelujah!

      However, I can't sleep, or focus, wake up with panic attacks in spite of alprazolam and tenazapam. I have an overseas trip to take in 13 days and I am staring at the bottle. I still can't fit into my clothes and I have the ONLY effective answer to my lifelong GAD, and my new panic and old insomnia staring at me. Has ANYONE that isn't built like a fashion model found a way to manage to fat MASS increase? Or weight GAIN? I am so depressed

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    • Posted

      I'm sorry Maria,I haven't been on this forum in quite a while,so it took me by surprise to see you messaged me.  But I've never agreed with just stopping Mirtazapine,I definitely think you should slowly WD,especially from 30mg.

      As for weight gain I personally would rather have weight on,than feeling ill.

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    • Posted

      This drug should be banned you need too reduce down every for too six weeks at a 10% taper 40 mg too 0.8 mg then cross taper on too fluoxitine take 0.8 mgs of mirtazipine at night and fluoxitine in the morning. Wait 6/8 weeks for fluoxitine too kick in stop mirtazipine and bye a antihistamine called sominex /phenergan take that at night it stops all withdrawal from mirtazipine. Trust me this is the only safe way too get of this devils drug its poisonous hell. It, takes years too taper ive done it

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    • Edited

      Oh geez, I'm sad to hear of the digestive problems that are coming up since you've stopped the Mirt. I am having them on a low dose of 7.5mg, and i chose to recently start back up on it two weeks ago due to the withdrawal symptoms. Unfortunately, i did not do my research before I went off, cold turkey, and became overwhelmed.

      Ughhhh, i will taper off slowly and get off them.

      I, too, have been thinking all week that i have IBS with the symptoms. Never had this before on the 15mg but it is not agreeing with me, and my stomach, and digestive tract is angry too.

      Unfortunately, taking any Western medication may relieve symptoms of one ailment, but then give us a totally different dis-ease or disorder as well.

      I hope you get sorted out soon. IBS is really awful, and keeps us close to home so we have to refrain from doing what we love outside of the house.

      Take care.

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    • Posted

      Did you notice weight loss when you tapered off mirt?

      I've been taking them for around 5 years (15mg) huge amount of weight gain and was thinking about actually trying the CoolSculpt, a new way of freezing belly fat but if the weight will come off naturally once I've tapered off them fully then it will save me the hassle.

      Thanks.

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    • Posted

      Hi david im new to all this how long after u stopped taking mirt did side effects go and how soon after stopping did u notice weight loss i was 20 st years ago i had type 2 diabetes i stopped my diabetic medication i lost 10st im afraid i may put all that back on i didnt know before being given the mirt it affects ur metabolism noone checked my medical history prior to getting them i didnt find out til after im actually angry about thattbh i wouldnt have taken them they were keen to just palm me off with them mayb i didnt need them at all please can u help me thanku

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    • Posted

      I stopped taking mirt on April 4 and didn't get any side effects luckily. I was on 15mg for 4 years and I tapered down to 7.5 for a month before stopping.

      Ask your GP if they can put you on something similar which doesn't effect weight OR as you said do you really need them

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    • Posted

      i had the same thing happen to me! i quit 30 mlgs of remeron cold turkey after almost three years i got new job so i been working more too but i have lost about 25 lbs in two months off of it my lymph node swelled up and i had some itching everywhere i thought maybe i had lymphoma cancer!! lucky my lymph nodes when down with antibiotics i cant eat as much as i was but on the meds id eat bowls of icecream at night an/or cereal cakes or anything sweet i didnt have much other withdrawal symptons tho

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    • Edited

      Hi David, how are you? I'm very much new with Mirtazapin, started almost a year ago and already feeling the side effects of weight gain and everything else that comes with that. I read your posts and I was just wondering how have you been after completely coming of 7.5? I've started to reduce myself from 15 to 7.5 for the last 4 days and I'm thinking about just going cold Turkey from 7.5 as I'm desperately to loose weight.. I used to not eat and suffering of insomnia before Mirtazapin.. how are you dealing with your eating and sleeping situation? kind regards M.Simoes

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    • Posted

      oh my god how awful to read all of this however i am glad i have i went on 7.5mg of mirtrazapine about 2 months ago i was very underweight so thought a few extra pounds would help however i have put on 2 stone in 6 weeks recently i have has really bad bloating , a rash, itchy skin ive been so worried i literally weaned off as fast as possible but i have seen doctors and they claimed it couldnt have been the mirtrazapine my lymph nodes were swollen im using diazepam for my anxiety and will never go back on these evil tablets again im suffering from the menopause and the rash and swollen lynph nodes have had me so worried as ive had cancer before im so angry that i wasnt warned about this i wish everyone a safe detox off this drug

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    • Posted

      Hello just got back from the hospital after chancing more blood tests for gastro issues.been going on for awhile, to the point ive checked for ever blood born viruses. bacterial even cancer plus an edescope and lined up to see a specialist surgeon,all My test have come back clear and healthy even..So doctor said no you don't get any issues stopping cold turkey,ive lost 6ks over 8 weeks but it level out and slowly going up.glad ive found this group ive been so worried that i am dying it's been driving me mad. .i had no idea why I've been so messed up., maybe now i can stop knocking on doctors doors.

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    • Posted

      I know this is 3 yrs old, but prozac (SSRI) will help with panic disorder, mood disorders & depression. It's helped a lot of people I know & might be worth talking to ur Dr about.

      The way my doctor explained Remeron to me is that it's an "A-Typical Antidepressant" that works to fill several receptors of the brain (good for me at the time bc I was making a lot of medication changes per neurological & psychiatric ailments) and that it would also help me sleep. I hate trying new drugs, it absolutely terrifies me. But of the different ones they kept telling me about, remeron seemed to be safest and could eventually help get me away from the benzos I had been using to sleep at night. Unfortunately, they didn't tell me about the weight gain, which has, in turn, caused more nerve pain than I previously had. I put on 20 lbs in 8 weeks on the lowest(15mg) dose. Went to gym 3-4 times a week& ate healthy but still kept gaining. I threw them away a cpl nights ago, deciding I'd rather take benzos for sleep then have all that weight on me. That weight gain bs just not good for u. Anyway, another one of the drugs they tried talking to me about at the hospital was Wellbutrin (antidepressant). I turned it down at that point but lately have been reading about & thinking of speaking w my (new) psychotherapist in regard to what I could expect from it & what my new regiment might look like/eventually turn into. From what I've gathered on the internet, Wellbutrin actually helps u lose weight... & that's the direction I'd like to be in lol

      Anyway, I know ur post was 3 yrs ago but I wish u well!! God bless 🙌

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    • Posted

      I know this is 3 yrs old, but prozac (SSRI) will help with panic disorder, mood disorders & depression. It's helped a lot of people I know & might be worth talking to ur Dr about.

      The way my doctor explained Remeron to me is that it's an "A-Typical Antidepressant" that works to fill several receptors of the brain (good for me at the time bc I was making a lot of medication changes per neurological & psychiatric ailments) and that it would also help me sleep. I hate trying new drugs, it absolutely terrifies me. But of all the diff meds they kept telling me about, remeron seemed to be safest and could eventually help get me away from the benzos I had been using to sleep at night. Unfortunately, they didn't tell me about the weight gain, which has, in turn, caused more nerve pain than I previously had. I put on 20 lbs in 8 weeks on the lowest(15mg) dose. Went to gym 3-4 times a week& ate healthy but still kept gaining. I threw them away a cpl nights ago, deciding I'd rather take benzos for sleep then have all that weight on me. That weight gain bs is just not good for u. Anyway, another one of the drugs they tried talking to me about at the hospital was Wellbutrin (antidepressant). I turned it down at that point-- but lately have been reading about & thinking of speaking w my (new) psychotherapist in regard to what I could expect from it & what my new regiment might look like/eventually turn into. From what I've gathered on the internet, Wellbutrin actually helps u lose weight... & that's the direction I'd like to be in lol

      Anyway, I know ur post was 3 yrs ago but I wish u well!! God bless 🙌

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