Mirtazapine (Remeron) Withdrawal Success Story!!

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Hello all!

I see a lot of taper / withdrawal threads on here explaining how bad it was for a lot of people but I wanted to share my experience with a relatively easy taper so those who google it don’t get completely terrified / hopefully it helps some people.

I was on mirtazapine for GAD and Panic Disorder for four years, 30mg for three and 45g for the final year. It helped a great deal in the beginning but the last six months or so I felt I was getting no benefits, so I decided to come off.

Here are my tips before I log my experience.

BE FIRM with your doctor. For too long I was pressured to stay on or even maximise my dose when I was unhappy. Tell your doctor you want off and you want off now and come up with a GAME PLAN.

GET ANTI-NAUSEA MEDS this one is simple, be prepared. I got a script for Maxolon from my doc to take twice a day during my withdrawal. It’s completely safe and non addictive and works wonders.

SET YOURSELF UP FOR SUCCESS you can do this. I personally have been through Valium (diazepam) withdrawal and it was horrifying, so with that experience behind me I knew this would be do-able. HAVE FAITH in yourself and your inner strength.

SYMPTOMS WILL PASS. The good thing is you know it is the withdrawal that is making your anxiety flare up or making you feel uneasy so you KNOW you can get through it and it will end.

So here comes my experience.

Had been on 45mg for a year (out of 4 on this med) and told my doctor I want off and I want off ASAP. They were aware of my success coming off diazepam so were supportive of me coming off this relatively quickly (I really earned my drug withdrawal stripes there haha).

45mg down to 30mg for five days. I took my anti-nausea pill when I woke up straight away and another in the evening if I needed. Honestly felt ZERO bad effects from this drop at all, if anything I felt better. Less violent anxiety, clearer head and happier mood.

30mg down to 15mg for five days. Kept taking those wonderful Maxolons and again this was a walk in the park!! Happier every day and really focussing on how much success I was having so far.

15mg down to 7.5mg for five days. Still on Maxolon every day to avoid the nausea. Had some days where anxiety would flare up quickly but that’s kind of normal for me anyway. Found on this low dose I was falling asleep so fast I had forgotten how sedating the low doses were!

7.5mg to 0 for the rest of my life. Still on Maxolon, have been noticing I still feel some nausea so I am grateful to have the anti-nausea meds to really minimise it. Have been taking 2 daily during this time. My sleep is becoming a bit more broken and less of a “coma” deep sleep now and I’ve been sweating bullets at random but DRINKING LOADS OF WATER.  STILL FEELING POSITIVE!!

I am now 3 days into 0mg and honestly it’s nowhere near as bad as a lot of people experienced and for that I am extremely grateful. Will update if people are interested to read how the next few days / weeks go now that I’m down to no mirt in my system.  It has been so much easier than I was braced for.

So here are a list of things I did experience.

Mild Nausea despite taking the anti nausea meds

Pooping more than usual

Some sleep disruption once I came off completely

Sweating

Mild headache (easily fixed by ibuprofen)

Flare ups of anxiety but NO PANIC ATTACKS caused by withdrawal, if anything my panic attacks are less frequent now

Feeling a little foggy headed once I got down to zero, not a big deal

Jitters. Just general fidgeting and struggling to sit still but that’s expected after being sedated big time for the last four years by a variety of meds now I’m on zero medications.

Things I NEVER EXPERIENCED

(I’m not saying these don’t happen but merely they did not happen to me)

Vomiting

Diarrhoea

Insomnia (I still sleep every night)

Brain Zaps

Migraines

Panic attacks caused by withdrawal

Suicidal thoughts / depression. I’m actually much happier.

Dizziness / feeling faint. Again this is less frequent now than it was while I was on 45mg.

Bad mood changes, being angry or crying for no reason.

So to anyone who bothered to read this essay post. YOU CAN DO IT. Everyone will experience these things differently and I am not disputing that some people have a really rough time, it’s just that when someone has a good experience or an easy time they are less likely to write about it. When I was starting my taper I found so many awful stories and so few positive ones which made me extremely anxious in itself. So I wanted to write out a successful withdrawal story for those people who are about to start to see that they might not have a horrifying experience and there are ways you can prevent a lot of the symptoms SAFELY.

Drink lots of water. Have faith in yourself. Be strong. Don’t put up with sh*t you don’t have to.

I am more than happy to reply to any questions people have about my experience and will update how things go for the next few days if anyone is interested. Cheers and good luck. 

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  • Edited

    UPDATE!!

    Well I'm now two weeks at 0mg and things have been pretty fine. There were two days just before the two week mark where I was quite emotional and had terrible anxiety but aside from that nothing major!

    My sleep has returned perfectly to Normal except I wake up earlier in the morning than I did when on mirt and my anxiety has been pretty much the same as it was on the drug. The weight I gained is yet to come off but it's only been two weeks so far and I've noticed I'm eating much less especially in the way of sugary treats!

    My anxiety is still giving me lots of issues and I was always open to trying a new med after mirt which I'm going to start this week, hopefully it does more for me than the mirtazapine was.

    Stay positive everyone and stick with your process, good luck to all of you!

    • Posted

      Thanks for your quick reply.  My drs suggestion is to UP the mirtaz to 15 and see if i feel better, tried this a year ago and got most awful zombie like feeling together with increase in anxiety, needless to say i dropped down.  Imdont reallynthink drs realise the difficulty coming off this.  She lauhed and said well i hope you dont ask me for liquid version as the health board would go bananas! Looks like its only in my own hands.  Out of interest what are they suugesting for you now?
    • Posted

      Hi Ann, I can't believe your doctor said that!! Doctors are all about money these days, they get you stuck on terrible medication then don't help you get off. Im in the same situation as you, i managed to get 1 bottle of the liquid but it only has a shelf life of 6 weeks and getting more was impossible so I went back to the tablet. I know lots of people on liquid in the uk so I suppose it depends where you live? I've reduced from 15 to 7.5 and 3 weeks on I'm not sleeping at all and my anxiety is through the roof, I suppose it effects ppl differently. How you coping?

    • Posted

      What new med are you trying for anxiety MirtSucessBaby?
    • Posted

      I'm going to try Pristiq (desvenlafaxine) which is an SNRI. I have previously tried to go on Lexapro but it made me faint three times in the first day so I can't go on SSRIs because of that! I'll be starting it tomorrow and can let you know if it helps the anxiety if you like? Once I've given it enough time to do its thing

    • Posted

      Sounds similar to you. Yes, down onto 7.5, dont think its doing much as i am not better. Wonder whether to try to halve it, but not sure thats a great idea when still down.  Do i ask for something else, weve tried several. I do get some sleep on this but still wake feeling terrible, are you bad every morning?
    • Posted

      How has it been swopping from mirtaz to pristiq? I am getting lower on mirtsz but anxiety not gone so will need something new.
  • Edited

    Hi is anyone still on this discussion for me to have some help?

    I am currently weaning off Mirt 

    I am currently taking 15mg until Friday then will start 7.5mg for 5 days then 7.5mg alternative days for 5days 

    Then coming off 

    I have anti nausea ( but I am a bit scared to take them too in fear of side affects )

    I really need off these tablets they have made me feel awful 

    Only been on them 5months at 30mg 

    So have already done one drop down 

    I have a horrendous fear of being sick and I am currently underweight 

    I want off this the safest way with least withdrawals 

    Any advice or positives for me would be great sad 

    • Posted

      Hi meg, nobody can say what will work for you we all reacting very different for cutting back medication. 50% drop is seems to much to me.

      I m coming off remeron for a 3rd times bc first 2 times I did to fast and end up many times in ER and went back on remeron. Now I'm coming off very slowly and dropping 10% every 2-3 weeks even 4 weeks if my symptoms very bad. Right now I'm only 0.6 mg and I'm still tapering. I was on only 7.5 mg for sleep problem. Never new it will be the hardest things to come off and I will have severe anxiety what I never had before.

      wishing you good luck and strength to come off this drug

      Eva

    • Edited

      Thank you for replying 

      I have been (touch wood ) doing okay on the 30 to 15 drop 

      I would never have started this horrid drug if I knew just how bad it was to get off sad feeling like I am loosing my head a little with fear sad 

      Hope you get off it this time ! 

    • Posted

      Don't be afraid!!! Fair is very negative though and it effect you on a negative way! 

      You have to tell yourself is going to be ok, alots off people came off this drug without any problem, I will too. 

      Keep cutthing until you feel something then slow down. Listen to your body, it will tell you, you going to fast or is ok. 

      Good luck with your taper

      love and healing

       

    • Posted

      Thank you! I appreciate your advice 

      An I hope you get off it without too much of a problem

      Hopefully soon we will both be rid of this horrible drug 

      Wishing you well 😊

    • Posted

      I have to say that you would do well to take Eve's advice, your dropping 50% each time is extremely fast, so yes your doctor is wrong so maybe do more research other than your docs advice.  The golden rule with tapering Mirt (and most AD's) is no more than 10% every 3-4 weeks - preferably 4.  And yes it will take longer this way but you will avoid the nasty discontinuation/WD symptoms and enable your mind/brain/body/CNS to find homeostasis gently.

      Best wishes.

    • Posted

      Hi Calmer,  what is the lowest dose you would advise to come off? 

      I remember you, you always give out good advise here in this board.

      Did you come off remeron? How was it after stoping?

      Eva

    • Posted

      Yes the anxiety is the worst part of lowering, no doubt about it.  How did you get to .6 is it liquid?
    • Posted

      No I'm dry cutting. Bought a Gemini scale and dry cutting every 2-3 weeks.

    • Posted

      How you getting on meg I'm off 2 for around 3 weeks feeling a bit anxious now n can't sleep xx

    • Posted

      I am in very much the same boat as you were when you posted this. I have severe emetophobia ( fear of vomiting) and when I started his medication about 5 years ago it was originally for my appetite. I was not able to eat due to my anxiety and depression. I have been very scared to wean off of this medication as I made the mistake of reading all of the terrible w/d others have gone through. Of course what concerns me the most is the nausea and vomiting. I also get pretty anxious when it comes to dizziness

      I have been on a quarter tablet for over one year and embarrassingly  the only reason that I am still taking it is because I was too scared to go through what everyone described. Last week, for the very fist time in the five years I skipped a day. This was a very big step for me. I did have a little bit of anxiety but I think that was due to me being so nervous about not taking it, I also developed a pretty bad migraine. My plan is to take this med every second day for two weeks then every third day for two weeks until I stop completely, I am pretty nervous, even though my dose is so low. 

      my pharmacist encouraged me and said that my dose is low enough that its not even getting into my blood but I don't know if I believe that. She just knows how bad I am with change and especially with what I have read.

      I wish I never started this med in the first place but I did really need something and it helped me at that time, I find myself putting off the wean because I get busy with work or something else comes up that I don't want to miss. It never seems like the time is right but I guess it will always be like that unless I isolate myself from the world completely.

      I hope I am able to do this because I really want to succeed and I hope that you made out ok.

    • Edited

      Hey! 

      I am sorry you are in the withdrawal process, but there is defiantly a light at the end of the tunnel, I did as I said took 30mg for a week then 15mg for a week then 7.5 mg for a week then took 7.5mg every other day for a week then stopped completely I used anti nausea pills through out an stopped them a week after I hadn’t taken any mirtazapine. I had no withdrawal symptoms nothing at all! An I have been off them months now! It wasn’t as bad as I thought after reading the horror stories! 

      I would really try it calm your mind, sometimes your mind makes you believe your having psychical symptoms. I hope you have a smooth ride getting off them an when your completly off them you will feel so much relief that it’s over ! 

      Good luck and I hope this helped a little smile 

    • Posted

      Hey! I am completely off them now! It was easier that I thought after reading the horror stories, sometimes your mind makes you convinced your feeling psychical symptoms! Well done for stopping them! Hope your doing well now! smile 
    • Edited

      Thanks so much for the reply. I was hoping that you would still see my post as it had been a while since you originally posted! 

      Wow! I am so pleased and also very happy for you that your wean was not terrible. That’s honestly so reassuring to hear your experience as there is not many positive testimonials out there when it comes to getting off mirt. I am going to continue with my schedule of every second day for a week, then every third day for a week and ultimately come off. May I ask if you had a prescription for anti nausea medication? Or was it over the counter ? In Canada it is called gravol in the us i believe it’s called Dramamine. I truly believe you are correct when you say the mind can make you feel physical symptoms. If you like I can update you on how i get on with this. I decided to finally make the initial step when the pharmacy told me that my generic brand was on a shortage of my medication. I freaked out because the other one i took made me have bad vertigo. Anyways, I’m rambling now. I can’t wait to be off and be free from this. I haven’t felt like myself in ages now and I’d like to get back there .

    • Posted

      That’s no problem at all smile 

      I understand how difficult it is when your weighed down by the fear of vomiting an needing to wean off the medication! I had many emotional break downs just at the thought of coming off mirt because of what I had read! But once I started the weaning I kept telling myself I can’t give up! I really needed off this medication an this was the only way I could so I just took the step! An thankfully was pretty straight forward! I am glad I have made you feel more postive about the process! Yes I had anti nauseas off the doctor He was quite understanding of my fears an my mental state which was good! I would defiantly give it a go getting some of those they were a life saver for me. You need to do what you feel is best for you, ( even though the whole thing is draining you know your own body ) the anti nauseas defiantly kept my phobia at bay which helped loads! Please keep me up dated yes! An I really hope goes smooth for you! If I can help any way even just to chat I’m here smile 

    • Posted

      I've been on mirtazapine 3 times cold turkeyed twice with basically no withdrawals the 3rd time I was on it a short time and had quite severe withdrawals that lasted 5/7 months I'm better now and coming off citalopram next  xx

    • Posted

      That’s odd isn’t it! Would you think the longer time on them the worse it would be! Glad your free of them now though smile 
    • Posted

      You would think rather *
    • Posted

      Its so nice to actually be understood about this. On one hand I can't believe I have allowed the fear prevent me from weaning but on the other I know it could have set me right back to where I was when I started taking the medication. Its even harder when all you read is horrifying reviews of pals withdrawals. 

      Today I am on my second skipped day ( I didn't take it last night). This week I will be alternating days. I think I will also be quite rattled when I stop completely. Was that hard for you also? I will be seeing my doctor this week for the anti nausea in prep for when I stop completely. It just never seems like the right time , you know what I mean ? there is always something on the horizon which requires me to be "on" that stresses me out too. 

      I really appreciate your support and replies. I will keep you updated with how I get on with this. Thank you for reassuring me and sharing you not so terrifying wean story. 

    • Posted

      wow , this is something. I would have assumed the opposite. If you don't mind me asking what dosage were you on  and for how long when you cold turkey as well as when you weaned? what made you wean the last time and what type of symptoms did you experience for 5-7 months. gosh thats a long time, sorry that you went through that.

    • Edited

      1, 3 years 15mg ct

      2, 2 years between 30mg and 15mg ct

      3, between 7.5mg and 15mg 8 or 9 days ct and was convulsing and had severe withdrawal 

      I have a Facebook support group if you would like to join xx

    • Posted

      Defiantly keep me up dated! 

      The anti nauseas will make you feel so much better an more confident to continue coming off them! I took them through out then a week after my last mirt I stopped them also. Do you take any other medications or plan to? If you don’t mind me asking ? 

    • Posted

      Hi meg. 

      Thanks for your post regarding the mertizapin. Since I last spoke things have taken a turn. I no longer take mirtizapan. Instead after numerous appointments with different doctors it was decided to change my medication and one of the changes was mirtizipan to clonazipan which now has me hooked because without them I have the worst panic attacks you can imagine. Essentially they’ve swapped one for another. Pretty much what they did before. I’ve tried withdrawing but the shakes are just to much. 😤

    • Posted

      oh no i am sorry to hear you are having a tough time! i hate when they swap a tablet for another, just the swap gives me terrible panic! with out even taking it ! so i understand how frustrating this must be for you!

      have you been back to your doctor to see if there is anything you could maybe try or even to explain how your feeling with it?

    • Posted

      I would love to join the support group Meg. Thank you so much

      also convulsions sounds absolutely terrifying, Im sorry that you experienced that.

    • Posted

      I certainly will ! Thanks for the reply. I will take the same precaution and take mine for a week or so after the last dose. I do not want any rebound nausea.

      I do not take any other medications. I dont even drink tylenol or advil. This is the only medication I have ever been on aside from antibiotis when I needed them. I do not plan on any other medications anytime soon. The reason I started taking this one is because my emet was so bad I had stopped eating and lost a lot of weight. I was also very depressed at the time. I can say that the mirt definitley helped me and probably even saved my life tbh. Ive just been too scared to come off of it because of the horror stories and my anxiety around being sick.

    • Posted

      Hi Richard, im sorry to intrude on your comment here but have you by chance tried supplementing vitamin B100 complex ? It is supposed to help a lot. My pharmacist is the one who had told me about this. She said a lot of ppl use it when coming off of medications to manage and reduce unwanted symptoms. Its worth a shot. I hope you are able to find some comfort and peace.

    • Posted

      the mirt didnt help me at all not even eat! thats why i was prescribed it also but didnt work i am still seriously underweight an now waiting to have a feeding tube fitted 😦

      i take a different medication now for my bi polar which i wasnt happy about starting another med but obviously i need medicating. i totally understand your fear for it making you sick even the thought of nausea scared me

    • Posted

      hi, i have severe emetaphobia too!

      i can deal with all the withdrawal symptoms apart from the nausea and sickness. im dropping 3.75mg every two weeks as directed by the doctor and for the first two days i feel sick to my stomach and thats the worse part for an emetaphobe!!

      i too was put on them to increase my appatite as well as depression they even increased me all the way to the full 45mg within a couple of month being on them.

      they made my anxiety around the emetaphobia 1000% worse and i ended up losing 2 stone whilst being on these tablets instead of gaining weight like everyone else does.

      i keep trying to fight it and trying to train my thought pattern so i can get through each drop im already on two lots of different antiemetics but i still feel super nauseous after each drop! 😦

    • Posted

      coming off them is awful especially when all you expect is the worst to happen, an obviously the worst is nausea an vomiting in our case!

      The anti nausea pills were my life saver i dropped a dose every week an i never had any issues with feeling ill which was a relief! i hope you get off them soon an it isn't to bad for you 😦

    • Posted

      what anti nausea pills are you taking?

      i take 1 ondansetron and 2 prochlorperazine in the morning 2 more prochlorparazine in the afternoon and then 1 ondansetron and 2 more prochlorparazine in the evening!

    • Posted

      Im sorry that you are going through that right now. Just try to remind yourself that every time you decrease you are one step closer to being off of them completely. Although I did gain weight whilst being on this med, it has started to come off now that I am reducing my dose. i was also put on the meds for my appetite, i had completely stopped eating due to emet back in 2013. It definitely helped me with my appetite but mostly at night after taking it. I was so surprised to hear you say it had made your emet worse because it seems like the same for me. i have become so much more hyperaware of everything and i fixate more on my emet.

    • Posted

      yeah it made me have severe panic attacks all the time and it convinced me that was going to be sick every day so i felt (feel) sick ever single day, iv completly stopped eating this past year also due to the phobia. the tablets never made me feel hungry. if anything it reduced my appitite even more. but that could be the anxiety over the phobia flaring up more than anything.

      iv managed to get to 30mg from 45mg but its been a huge struggle! but i keep telling myself iv done really well to get to this point! just keep going!

    • Posted

      i was taking the prochlorparazine didnt need anything else, i dont take them now i am fully off mirt now so stopped taking anti nauseas also

      it takes time but believe me you will get there an its so much of a relief when your off them fully!

    • Posted

      oh wow thats really impressive,

      did it ever make you sick? people say they stuggled the most from 15 and down how was that for you?

    • Posted

      to be honest i never had an issues with any of the drops

      nope never made me sick an never suffered any nausea

    • Posted

      you are so lucky!!!

      im nausous for about 2/4 days after each drop whoch i suppose isnt too bad but its bad enough for an emetaphobe aha!

    • Posted

      i totally get what your saying any kind of stomach pain sends me off in to a panic !

      i really hope it gets easier for you ! an you dont suffer much more with the nausea !

    • Posted

      im the same any feeling i get in my stomach i panic!

      the drops are making me feel good in my metal state though which is a plus im not having panic attacks like i was when i was taking 45mg iv got some anxiety but no where near as bad.

      i can deal with all the other side effects well. people say their sleep becomes bad while tapering but that dont bother me iv got a doctors appointment tomorrow im going to ask if there is anything different i can take for the nausea, if i can get that under control i can sail through coming off this drug!

    • Posted

      how long the withdrew last? i am on day 7 dropping off. very bad anxiety . please help me

    • Posted

      Hi! It's been a year since this but just want to rant and feel understood I guess.

      I have TERRIBLE emetophobia and I've been taking 30mg for a year.

      Gonna take 15mg today since my psychiatrist told me that since it's not giving me any benefits it's better for me, I obviously told her I was scared of the withdrawal symptoms but she told me that not one single patient she had said they had problems with tapering it off. I was quite positive but I just searched stuff on the internet and after reading this I'm TERRIFIED of the nausea. I do not have any prescription for antinausea meds and the doctor doesn't open til Tuesday! I have no choice in taking 15mg today because I finished my 30mg pills 😦

      I'm so anxious and terrified of throwing up because of the withdrawal..... Shouldn't have just believed the doctor and not read anything else I'm so upset

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