Mirtazapine withdrawal? 6 weeks off.

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Hi guys and gals,

I'm happy that I found this website.. Makes me feel like I'm not totally alone in this :-)

I was on Mirtazapine 7.5mg for anxiety and insomnia for more or less 1,5 years. Tried to go off a few times, but it never worked out.

This time I did a slower taper...

From 7.5mg to 3.75 for 6 weeks - no trouble

From 3.75 to 1.8something (hard to make smaller pills than 3.75) for 6 weeks - not much trouble although I was a little fatigued.

And then from 1.8mg to ~0.9 for a few weeks until I said to hell with it because they were tough to split to this size.

So 6 weeks ago or something I took my last dose. It went alright the first weeks I think, I don't remember complaining about it during that time.

Right now though I'm facing broken sleep, VERY fatigued, and some anxiety, and I guess being fatigued makes me depressed.

Is this still withdrawal or is it something else cooking?

Any anecdotes?

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41 Replies

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  • Posted

    Should I reinstate or keep going? What do you think?

    I would really hate to reinstate at this point.

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    • Posted

      i did 3.75 now for three months. Plan to go to 1.88 after holidays and hope to stay there for some time if i can bear the sleeping problem alongside anxiety.   Maybe you could reinstate to lowest level and see how it goes.  Its a personal decision and listen to your body. I still have anxiety and no other anti dep in my body, sometimes dr gives a different one but im trying to manage as he says i am anxious not depressed, i think jurys still out on this one.
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    • Posted

      I am on warfarin and dont know if i can take this oil.  I am not sure whether to ask GP this question as it may not be prudent to do so.  Anyone i can ask as to whether i can take it thatnyou know of? Also i hear there are food and bad ones, i need info on where best is available, dont mind cost to feel better.
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    • Posted

      Kc2325  are you in UK just wondered where you got CBD  oil, and how much you take etc and any type to use , i am interested in trying out as starting Mirt taper and will need all the help i can get i think

       

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    • Posted

      I use a locally sourced oil but there is a company in Colorado that manufactures Charlotte’s Web that is very popular. They do ship.  
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    • Posted

      hi i take mirtazapine for to help me sleep and would love to be off it .   sorry could you tell me what CDB OIL  is  and how you take it or use it.. sorry but i don't know .thanks

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    • Posted

      CBD oil is the cannabinol soul that is harvested from hemp plants and has many health benefits. I’ve been using it for over 2 years. It helps with my sleep, anxiety, blood sugar and cholesterol. Probably lost of other benefits that haven’t been measured in my body as well. 

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  • Posted

    That sounds like classic WD symptoms to me. I used ambien during the worst of the insomnia and then Phenergan. I also use CBD oil each night to help with sleep. Hang in there. It does get better. I’m off a full year now and am glad I went through the horrendous WD symptoms. Life is much better for me now that I’m off Mirt. 

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  • Posted

    Welcome to withdrawl. Ride it out. You can do it. Stay way positive and ultra busy. You got this.
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    • Posted

      It's the fatigue that is really kicking my ass. It's making me really really depressed, but how can you not become depressed when you're so fatigued that you are almost unable to keep your eyes open.

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  • Posted

    Sounds like classic WD to me. I used other sleep aids during the worst of the WD to help get me through. I tapered for a full year and still had pretty severe WD so we each have a different experience. Give it time and just know it will pass with time. 
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    • Posted

      I had fatigue for about 5-6 months after getting off. Also mental ups and downs. Honestly, what helped me most was when I started juicing. Cucumbers, celery, apples and a bit of ginger. I think it helped my body to heal faster. 
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    • Posted

      And I had horrid WD for 3 months and another 3 months of ups and downs. 
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    • Posted

      Ouch... that sounds like a long time!

      What dose were you on and how long? And how did you taper?

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    • Posted

      I was on for almost 4 years. It took me a full year to taper after a CT stop that was horrendous. I had a local pharmacist make a liquid compound to help with the taper  This allowed me to reduce by smaller amounts, especially when I got to the lower doses. 
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    • Posted

      I also tapered down to 0.25 mg and held for a month to get as stable as I could before the jump. Months 2 and 3 were the worst for me but I have a great support network that kept me from giving up on myself. 
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    • Posted

      I also tapered down to 0.25 mg and held for a month to get as stable as I could before the jump. Months 2 and 3 were the worst for me but I have a great support network that kept me from giving up on myself. 
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    • Posted

      I had some  WD symptoms during the taper.  Day 3-4 is when they would start. It was mainly mental waves and windows. I would wait to stabilize, which generally happened around day 10-14. Then I would reduce again. 

      And I was fatigued during the taper. But, to be honest, I always felt fatigued on Mirt. I had no interest in any exercise. That passed after being off for 6 months. I now regularly exercise again and eat healthier and more than while on Mirt. 

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    • Posted

      As i am feeling very anxious and a bit down and I have only got down to 3.75 do you think its ok to drop a bit further, or do i need to ride this storm which is getting more difficult for longer.  I presume it will all happen again when i drop a bit further.  I am waking with such awful dreams and feeling i cant face normal life as everything frightens me, where has this fear come from, i just dont know, is it the mirtaz or the illness.  I didnt tolerate other anti deps well. More than three years on now from onset.
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    • Posted

      The dreams are from the mirtazapine Ann I get them all the time. Also wake up most mornings wet from sweat. And I know of a few other people that suffer from fear since taking this tablet.
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    • Posted

      Are you still taking it, or decreasing? I thk the nimares are a little less since lowering.  My goal is to get off it as psych suggsed, not so easy though.   I wonder if the fear goes away after it is stopped.
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    • Posted

      Ann, I was also incredibly fearful while on Mirt. I thought it was me but I’m much better now that I am off. And that constant underlying anxiety has also lifted. 

      I believe all of my issues were caused by heavy metals which were released after I did a liver cleanse. My son also had heavy metal poisoning which made him very ill for 18 months. We are now on a diet which help the body to gently detox and restore the gut function. My whole family now feels so much better, I can’t believe it so I am now a big advocate of very clean eating. We juice every morning with specific food items, and cut out sugar, gluten and dairy and have cut way back on meats. Our diet is primarily plant based. 

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    • Posted

      I've been On 15 mg for 4 months Ann. I swapped straight on to this off amitryptyline. I will be starting my withdrawal very soon. Some days I'm more anxious than others. I really need to get off this as it doesn't do anything for me not even any help to sleep.

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    • Posted

      I didn’t for me. I think my brain was not able to process the information properly and it resulted in anxiety. I had a host of issues while on Mirt which, thankfully, had now mostly resolved.
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    • Posted

      I heard Ann more than a few people say they didn't have anxiety before taking it. I feel more anxious since I started taking it yes. I'm also a lot more irritable since taking it. Makes my skin feel like it's burning and a few other unwanted side affects.

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