Mirtazapine withdrawal effects

Posted , 5 users are following.

This discussion has been locked due to a period of inactivity. Start a new discussion

I've been weening off Mirtazapine from a high of 45 mg down to 22.5 and tried 15 mg but I've felt horrible and feel like I'm walking around in a daze and only getting about six hours of sleep a night. Has anyone else had this issue and can you tell me what to expect going forward. Thanks!

2 likes, 32 replies

Report

32 Replies

Next
  • Posted

    Hi Rob

    Sorry for your suffering Rob.  Did you literally go from 45 to 22.5r then to 15mg?  How long did you hold at each dose?  How long have you ben at 15mg?

    The thing is, if you taper too fast your brains rewiring doesn't have chance to catch up, I would keep a journal of dags of the tapers and follow a plan.  For starters, click on my name & get the informed choice of how to taper etc - from the links under my status.  

    Yes, being in a daze if sure one of the WD symptoms, yor sleep should return to normal when you are readajusted or stabilised after the drop in dose.  

    Hope a little of this helps.  Wishing you well.

     

    Report
    • Posted

      Thanks calmer and I went from 45 to 30 before going to 22.5. I just started on 15 mg and I will definitely check out your plan. Thanks again!
      Report
    • Posted

      45 for a month, 30 for 4-5 months, 22.5 for two weeks and I'm just starting 15 mg.

      Report
    • Posted

      We delete content if it doesn’t meet the requirements in our Terms & Conditions.

  • Posted

    Rob I was on 45mg, I reduced by 7.5mg every 3-4 weeks. I haven't had any ill-effects, I'm on 15mg at the moment, I'm staying on this for a while longer because of some family stresses. I'm hoping to continue reducing in December when I will go by smaller increments as my body learns to manage without the drug.

    Report
    • Posted

      Thanks Catherine it sounds like I'm trying to rush along the process too fast I guess, hopefully I can get this figured out and finally be rid of all the side effects I deal with and get back to being me again. 🙏🏻

      Report
  • Posted

    Hi rob

    I taper them too fast

    I was in a restaurant siting down when it got really noisy ,my mouth went dry then my head went all dizzy then I passed out !!!!!

    Ambulance arrived tooked me to hospital and got checked over and it was all down to coming off mirtazapine !!!!!!

    Take care

    Christine CRPS uk

    Report
    • Posted

      Rob I should have suggested asking your GP to prescribe 30mg and 15mg in place of 45mg tablets. When I said I reduced by 7.5mg it was using a combination, breaking the tabs in half to achieve the required dose. I also drew up an idiot chart to follow, with planned dates and doses. I found this helped me to track my progress and to avoid the temptation to rush the reductions.
      Report
    • Posted

      Thanks again Catherine, and it sounds like making a chart would be a great idea I'll definitely give it a try.

      Report
  • Posted

    Hi Rob,I'm sorry to hear you're having some issues with Mirtazipine,like you I was only getting 6hours a night sleep and for me it got worse,I was managing to go over to sleep at 4am until the night before last when I couldn't go over at all,the doctor had to give me a prescription to sleep,it's been 3weeks since I stopped talking Mirtazipine,no-one has said if the symptoms ease,I only hope they do.

    If your worried talk to your GP about the sleep,I hope things get better for the both of us. Take care.

    Report
    • Posted

      I'm sure my symptoms will probably be with me the whole time while I ween down but it has been tough and I've been getting headaches and flu like symptoms daily which is hard but I hope it gets easier for both of us real soon and thanks for letting me know about your experience.

      Report
    • Posted

      Hi again Rob & all

      Those flu like symptoms may well be wd, they last a week or two ... if I were you I would stay at that 15 mg dose for the full 4 weeks; as you were only on 22.5 mg for 2 weeks you will still be feeling the effects going from 30>>22.5, let along 22.5>>15, so yes, try and be kind to yourself and slow it right down, that way your sleep should return.

      For anyone else tapering also, you can ask for Mirtazapine (Remeron if in USA) "Sol Tabs" - they dissolve in water and it is easier to taper in small amounts - 10% is best every 3-4 weeks, that way its easy to avoid wd symptoms.

      Vikki, sorry to hear you are struggling to sleep - how did you taper Mirt?  Are you off Mirt now?

      Report
    • Posted

      I'm going to try to go to around 18 for now on the Mirtazapine for a little while before going back to 15 as the wd symptoms are hard to deal with while I'm still working. I've been put on 1.0 mg of clonazepam to help even though I don't like using the both of them together. Thanks again for all your help as I appreciate any input I can get.

      Report
    • Posted

      Hi,yes I'm off the Mirt now,3weeks,I panicked,I was overwhelmed by the feelings,they were so real,I've never experienced Anxiety like this before and could think of nothing else other then getting my life back,the Anxiety didn't come until 10days into stopping,id think it was getting better then Wham! It hit me,Wednesday was hard for me especially when I couldn't go over to sleep at all,my GP prescribed me Zopiclone for a week,I'm to take it for 2 night then I'm to try sleeping without for 1 night,if I still can't sleep I'm to go back,do you know if you brain re-modifies and goes back to how you were. I'd really like to know??Thankyou for taking the time out to comment,it's been the hardest time ever for me and knowing I'm not alone has been really comforting. Vikki

      Report
    • Posted

      Vikki I'm sure your brain remodifies itself eventually but I guess it works differently for everyone on how long it takes. It is comforting to know that other people go through some of the same struggles and I know what to expect for myself. I hope you get better quickly and it goes a little easier for you in the future!

      Report
    • Posted

      Hi Vikki

      So sorry, jumping off Mirt' quickly isn't for the faint hearted ... ugh ... not the easiest way for sure.  I have read so many times on this forum of people "just wanting to get it out of their system" - and it just doesn't work like that.  I will PM you a link to read rather than copy & paste as any c&p would probably be removed by the moderators.

      Once you've read it you might want to reconsider, maybe reinstate at a lower dose than you were on last.  The short answer to your question is yes, certainly your brains neurons will remodify but it can take a long time - did you read the links on my status?  

      Anyway, I will pop that in your message box now.  I think the insomnia can be the worst of all symptoms, some folk take Zopiclone for a month or so, but then it means weaning off that also, which may not be so bad.  

      What was your last dose of Mirt Vikki?  How are you feeling today x

      Report
    • Posted

      Hi,thanks for commenting,I've been off the Mirt 4weeks nearly and as you can imagine I've been through a terrible time,the Sweats have eased a little,I was overwhelmed by the Anxiety,I'm a very logic person so when the Anxiety left my mind feeling like life was a game and the Matrix was real I went into Panic..I didn't think my mind would be able to get back to what it had always been..I thought my mind had gone to far!!

      I started to cope with the anxiety and I was sleeping (only on a good night )6hours,about 4am I would finally go over to sleep until the other night that is 4am came and went and the next day I still couldn't go over,

      My GP prescribed me zopiclone for a week, I'm to try going over to sleep without taking one Tonight,my Gp wants me to go back if I still can't sleep,I don't want to go on a low dose of Mirt as I've done 4weeks without,I was on taking 15mg to start with,god knows what I'd of been like if I'd been taking a stronger dose.

      Thanks again any input really has helped,the withdrawals off Mirt is hard but it was even harder when I thought I was alone. Vikki

      Report
    • Posted

      Sounds hellish, bless you.  Some people use Benadryl or Pherergen for a sleep aid, it can make youu drowsy and is available over the counter in the UK; got a feeling you are not in the UK?  

      Have you had any nausea or itching??

      You are not alone, so many people suffering coming off Mirt, doctors have no idea I don't think what we are going through.

      Report
    • Posted

      Hey,yes I live in the U.K.,Kingston upon Hull,I've had no stomach cramps,nausea or itching,I've recently started with headaches tho,

      I've just read your links and thanks again for the inbox,it's been really helpful.

      I've never experienced the dyscooredination of the body and mind before,I didn't know such a thing existed,

      How wrong was I to think antidepressants work like an aspirin,

      I want to see it through now as I've not taken a dose for 4weeks,I know to be patient,it's still early days for me,I just really want my life back,

      One thing I have learnt from this is that feeling depressed is something that should be dealt with by changing life circumstances not by getting a quick fix with meds from a Gp. Thanks again Vikki

      Report
    • Posted

      Here here, I agree ... meds are ok short term I think for certain people, although most docs' recommend to stay on AD's for at least 6 months or sometimes a year whilst you sort out these changes, some people don't have the choice as they can be so desperate. 

      Hope all goes well for you from here, let us know smile  

       

      Report
    • Posted

      I agree totally wish I never let myself get to the point where I needed medications but sometimes I guess depression doesn't give us the choice..

      Report

Join this discussion or start a new one?

New discussion

Report as inappropriate

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up