Mirtazapine withdrawal horrendous

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Hi!  I have been off and on Mirtazapine several times over the past 14 years.  I have also taken Gabapentin (off 2 years), Zoplicone (off 2 years), and Seroquel (off 11 months).  I have now been off the Mirtazapine for 4.5 months and the w/d symptoms have been horrific (chronic insomnia, burning, tingling, numbness, vibrations throughout body and head, adrenaline surges, depersonalization/derealisation, myoclonic jerks, burning brain, feeling like I'm either going 2 drop dead or go insane at any moment and the list goes on.  I have had a few windows the past couple of weeks, but it very soon goes back to being extremely debilitating, painful, terrifying and horrendous).  I am feeling extremely weak, exhausted and hopeless. 

Has anyone else suffered so horrendously getting off this poison and if so what did you do to manage your symptoms so they were at least tolerable?  As I am extremely paradoxical to almost all psych meds and a ton of other pharmaceuticals, going back on any drugs is out of the question.  I don't want to have to live through another w/d like this for as long as I live which may not be much longer if I soon don't start getting some regular sleep.  At best now I might get 2 hours per week.  Please answer as I am desperately in need of some advice and support as I am getting weaker by the day.  Thank you.

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  • Posted

    I would suggest you see a specialist as you cannot go on like this.You may need Temazepam  or something similar to get your body back into a regular sleep pattern. I really feel for you but I take Lexapro and that is very good with little or no side effects.See your doc ASAP. Best of luck.
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    • Posted

      Hi Alison46649!  Thank u 4 responding 2 my post.  Unfortunately, I react badly to almost all psych meds and most pharmaceuticals.  As I have had some windows while coming off these drugs, I am hoping that my sleep will eventually get back to normal.  I have seen on some other forums where people have gone 4 months without sleep while w/d from these poisons and have been o.k. in the end.  If I were to start on another drug it would just mean I would have to go through this all over again as all these psych meds have horrendous side effects and w/d symptoms and I am not prepared to do that.  I am currently seeing a really intelligent, knowledgeable, caring and supportive herbalist who knows about these drugs and has helped quite a few get off them safely. 
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    • Posted

      I react badly to all drugs as well. I'm one month off mirt and feeling absolutely horrendous. I'm not sure what to turn to next. I have had windows but this week I think is the worst I've felt mentally. Let me know if you find anything to help. I cannot take another AD as the start up effects are so bad for me and also they usually make me more depressed. Please let me know how you are doing.

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    • Posted

      Have you tried CBD oil or paste?

      I’m withdrawing from this horrific drug to and it’s hell I started raking CBD oil as they say it relaxes you I’m not sure if it’s working but I’ll try anything natural as never want to go back on prescribed medication again 

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  • Posted

    Hi Barbara, I'm sorry you are going through what really does sound like hell.  How long have you been off the mirt?  How was it coming off it in the past and how long did you go before going back on?  Did you have trouble going back on?  What dose did you come off this last time and did you do any tapering or cold turkey?

    There is nothing that can hasten healing from withdrawal other than time.  Believe me, I've been around the withdrawal boards and if there were anything that really did it, I'd know about it.  Very reluctantly, I will say that there is one doctor on a website which I'm not allowed to mention who will use benzos very judiciously to help people weather the worst withdrawals (better than taking your life!) but taking z drugs or temazapam may go paradoxical on you and certainly would cause a new dependency if used with any regularity.

    Two small things to do to support yourself in WD are to take magnesium and omega 3 fatty acids (fish oil), both good for the neurons. Reinstatement is really the only thing that can fix the symptoms, but it doesn't always work once in the throes of a horrible WD.  If you did end up wanting to try it, you'd not want to go back to a full dose in case it does trigger an adverse reaction; you'd do a few mgs to start.  

    It sounds by what you've offered that you've been around the wd boards, too.

    The main thing is to do whatever you need to do to be gentle and kind to yourself.  If you need to be on the couch all day, that is fine.  Be kind to yourself.  Some find mindfulness helpful.  I can never get my brain to quiet down for it for very long but I find telling myself that I can take one moment at a time.  Try not to think in terms of weeks and months.  Try to be present and not allow your brain to engage in rumination which causes more suffering during WD.  Allow yourself to be distracted by any means.  An epsom salt bath may be soothing, especially before bed.  I always find a cup of warmed milk before bedtime to be helpful. Finally, I've found "tapping" to be helpful when having a bout of insomnia, otherwise known on the web as emotional freedom techniques.  It takes a 3 or 4 rounds of tapping before I fall back asleep, but I always do!

    I'm sorry I don't have any magic bullets.  You know that healing happens in windows and waves (you've alluded to windows), and as bad as you're feeling now, you know "this too shall pass."  A mantra that I've used that can make one feel better is to repeat "Do not judge; minimize harm; know it will pass."

    Keep us posted!

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  • Posted

    Hi Barbara

    I'm really with you believe me.  I'm in the same boat as you.  I stopped mirt nearly 5 months ago, end of May.  I was on 15 mg and on it for less than 6 months.  I just went cold turkey because I didn't realise how evil the withdrawal symptons would be.  I've had not much support from the GP and the worst bit is the crippling insomnia night after night.  Some nights I might get 2 hours, others, I'm awake the entire night.  I can't even manage to fall asleep when I go to bed, so if I fall asleep in front of the TV for 2 hours, I take that as a positive.  This drug is renowned for its windows and waves and whilst you are really battling right now you have to hold on to the belief that you will get through it.  I know it's hard.  It's certainly one of the hardest things I've ever experienced.  In month 4 free of mirtazapine, I was fine.  No anxiety, no low moods, and I was sleeping without Zopiclone (I would take small half doses when I was desperate). I really thought I'd cracked this drug.  Then about 2 weeks ago the insomnia was back with a vengeance along with the headaches, churning guts and anxiety.  Like you I've felt I just can't go on like this, I cannot believe that a drug can have such a stranglehold over a person's mental and physical health after nearly 5 months.  I'm not on any other AD.  I take magnesium supplements, get walking every day and have now started a mindfulness course.  Like you I will NOT go back to taking these head drugs.  However feeling in the depths of despair through lack of sleep, I'm going back to the doctors to insist on some tests.  I'm drug free, look after my diet, exercise every day and am on week 3 of an NHS mindfulness programme.  The GPs don't acknowledge there are protracted withdrawals from mirtazapine so going back and insisting upon further investigation is the only way forward for me.  The regretable thing is.......before I took this drug, I never had a problem with sleeping.  What I'm saying in a really long drawn out way, is stick to your guns, go back to your GP.  I really feel for you Barbara because the pair of us have stuck this out for so long and it is soul destroying to see hardly any improvement.

     

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    • Posted

      I am not quite at your atage yet, down to 3.75,tried tomget down to 1.87 but was so bad had to reinstate.

      i feel for you and just want to get off this.  I am waking in night internal,shaking and need to take diazepam to try to stop it.  Have you any help in advising me how to get off this, should i go cold turkey or keep slowly dropping.  I know as i get worse the pdoc will,just throw some other drug at me and like you i dont want to go down that route.  I feel,like my whole CNS has beeen assaulted and cannot recuperate, i was on 7.5 cor rwo years, never really worked either.

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    • Posted

      Hi Ann

      I wrote you a message earlier and it got lost in the ether.  You are right when you say your central nervous system has been assaulted.  That's exactly how I feel right now.  The trouble is mirt has a very protracted withdrawal and most people don't realise it takes months and even years sometimes to get off this drug.  I wouldn't advise cold turkey.  You have to be gentle with yourself and taper slowly.  I know that sounds very frustrating but believe me when I say that I am 5 months into cold turkey right now and I will be honest and say it is dreadful.  In month 4 mirt free, I was feeling great.  I'm not on any other ADs and I was getting along with just supplements.  Two weeks ago and BANG the withdrawal is back.  Insomnia is the worst and I'm really struggling.  I would advise that you taper by 10% per month.  I'm so desperate at the moment that I've just begun a mindfulness course.  I exercise everyday, I've seen a counsellor and my diet is good.  After 5 months I would expect to feel much better than I do. But I'm not taking anymore ADs. As the doctors don't recognise withdrawal on these drugs, I've made another appointment with the GP.  This time I will present them with all the things I have been doing to help myself and firmly request tests be done or referral to a specialist.

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    • Posted

      We spoke a while ago.  I am now almost off mirtaz but having w/d symptoms already.  I am so over anxious and feel like death.  I am trying to keep a routine up but its very hard. Appetite is starting to suffer too.  I have been slowly dropping since August but this is the worst. I feel like im going mad sometimes. Dr gave me valium and i take 5mg to sleep. Another detox needed if i ever get over this

      how are you getting on now, happy to hear even the bad bits.

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    • Posted

      Hi again Ann

      Hang on and do what you need to do because it does get better.  I have been off mirtazapine now for 7 and a half months and can finally say I feel so much better.  It has been a very long and difficult journey.  No withdrawal support from the medical profession whatsoever.  They just wanted to give me more ADs.  I stopped taking mirtazapine and went cold turkey in May 2017.  I'm completely drug free apart from taking HRT for the menopause.  I felt exactly like you at month 5 and 6 of withdrawal.  And my main issue was horrendous insomnia; it was torture.  I would take Zopiclone for this.  The GPs do not want to give out sleeping tablets.  They say they are addictive!!!!!!!!!!!  And ADs are not?????????????  Absolute rubbish.  It's no coincidence that as I write this to you government ministers are investigating a Britain hooked on prescription drugs.

      I have been sleeping much better at night but it has taken me 7 and a half months to feel normal.  All the other withdrawal symptoms have long since gone. 

      Please feel free to message me if you want anymore information.

      It really does get better

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    • Posted

      So good to hear you have cracked it. Its just so hard when youre in the middle of it all and the fact that your gp and psych says there is no withdrawal!   I am trying to keep going and hoping the days will get better.  I still will have the diazepam to taper, oh my goodness!
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    • Posted

      One thing I have learnt going through this is; be kind to yourself.  Do not beat yourself up or focus on the fact that you have the diazepam to conquer right now.  If diazepam helps you, you take it.  You can only work on one drug at a time.  In my experience mirtazapine was far worse than worrying about being addicted to Zopiclone.  I did see a counsellor during my withdrawal who put me on a mindfulness course.  Mindfulness does help with anxiety but you have to try to be disciplined about practising.  I understand your feelings of despair after such a long time battling this drug withdrawal and you often feel completely alone.  I was at my wits end.  My life was on hold, I had suicidal thoughts being awake every night and nobody got it nor understood.  It will pass.  It will get better and it's not you; it's this nasty, evil drug withdrawal.  Bear in mind that there are very many people all battling this.  We are not attention seekers or flakes.  Some people struggle for years to be free from mirtazapine.  I told myself that if I had to mend a broken bone, stop smoking or lose weight; these things take time, at least 6 months and longer to feel and see  results.  This drug is renowned for its protracted withdrawal so take it one day at a time.  

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    • Posted

      Thank you for your advice.  I am hoping to be free of this mirt in the near future, but i think the psych will try to use something else and from my track record i just cannot take so many of them.  I am trying to stay strong but its been so long that i am finding it daunting.  Even the thought of going on a course for mindfulness is a terror to me just now.  I am also,having stomach problems which doesnt help.  Imdont understand why my psych said just take a few weeks to halve then quarter it when its known everywhere i look that protracted withdrawal is the norm.  
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    • Posted

      I completely understand Ann.  I was terrified of joining a mindfulness group which I think initially pushed my anxiety higher but I was so desperate for anything to tackle the insomnia that I told myself I will just go once and try.  If I can't cope I won't go back.  I know the medical profession can't or won't admit that these ADs present with protracted withdrawals because they must have been told to push them by the drug companies.  I know it's very hard for you right now and it's hard to find comfort in anything but remember it will not be like this for ever.  

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    • Posted

      How you getting on with your sleeping now. I am going through hell now can't sleep everything you've said I've got it now stopped mitrazapine about 8 weeks ago n I'm suffering for it now x

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    • Posted

      Hi Karen

      How long did you take mirtazapine and what dosage?

      Generally my sleep is better.  But I still get days when it is very poor.  For example in the last week, I’ve had two nights when I’ve had only 3 or 4 hours sleep.  That is very upsetting and I know it’s all connected to taking mirtazapine.  My sleep is not as good as it was before I took them.  But much better than say 4 months ago.  

      I take zopiclone if I need to.  They don’t give me side effects and I can take one for a couple of nights and then just leave them.  I find they are far less dangerous than mirtazapine and have helped me cope with 10 months of withdrawals.

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    • Posted

      Hi all....

      I posted on this subject some time ago now after a horrendous journey on and and coming off mirtazapine... After Year's of utter hell, I discovered several things..... Firstly why we suffer from thease conditions in the first place. Secondly why our bodies react the way they do to thease horrid toxic pharmaceuticals and thirdly how to fix it. I strongly urge you all TO watch the following video and feel free to contact me for more help. God bless.... Time to know the truths...

      ...

      ....... Dr Robert morse YouTube.. Deppreshion anxiety and insomnia...... This is just the tip of the ice berg but very simple to fix

      Moderator comment: I have removed the link(s) directing to site(s) unsuitable for inclusion in the forums. If users want this information please use the Private Message service to request the details.

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