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Any others here taking this combination of drugs?
I have had knee problems off and on for about seven years. Yesterday my doctor decided that my cartilage has finally 'Gone', probably finished by getting off our local trains where not only do you have to Mind the Gap but have a good two foot step down. He is arranging for another X-Ray prior to discussing my surgical options. Meantime he reluctantly prescribed an NSAID ( Naproxen) after considering my BP and past stomach ulcer and other problems.
Reading the packet insert it tells me that Losartan and most hypertensive drugs may be affected by how NSAIDS work.
Googling Naproxen + Losartan I read, "Significant interaction possible (monitoring by your doctor required).
losartan oral , naproxen oral . Either increases toxicity of the other by Other mechanism. Combination may reduce kidney function, particularly in elderly or volume depleted individuals.
naproxen oral decreases effects of losartan oral by opposing drug effects. Combination may reduce blood pressure reducing effect"
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