PAE for BPH
Posted , 15 users are following.
How long is PAE effective?
0 likes, 62 replies
Posted , 15 users are following.
How long is PAE effective?
0 likes, 62 replies
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zhangyolo don30615
Posted
There are several treatments for prostate gland enlargement. like diuretic and anti-inflammatory pill are two natural therapies. Thus, which is better for BPH, the herbalist Dr. Li Xiaoping will answer it for men.
Thermobalancing therapy works by continuously improving blood circulation locally in the affected organs over a prolonged period of time. The working principles are similar to acupuncture, massage, activating blood and resolving stasis of the prostate.
However, it can only relieve the symptoms of prostate gland enlargement, it cannot cure BPH thoroughly. Clinically, untreated BPH can cause some complications like dysuresia, blood urine, even kidney problems. Thus, thermobalancing therapy is usually considered as adjuvant therapy for BPH. Besides, due to the process of messaging prostate, there are likely to bring in some bacteria to the prostate, which can aggravate the infections of the prostate.
Clinically, semen is mainly from the prostate. Thus, prostate problems like BPH can cause semen problems which would lead to male infertility. The herbal pill like this herbal medicine contains some herbs like Plantain Seed, Houttuynia cordata, Cowherb Seed, which can clear away heat and kill bacteria. It can kill the bacteria of the prostate, preventing the occurrence of male infertility.
Besides, the enlargement of prostate gland can make the prostate congestive, which can eventually trigger some serious complications. The herbal pill contains some herbs like Safflower, peach seed and Angelica sinensis to activate blood and resolve stasis, which has the functions of activating blood and resolving stasis, softening hardness and dissipating mass. It can relieve the symptoms of prostate gland enlargement effectively and treat its complications like UTIs etc., even can prevent the prostate calcify.
What is more, the formula-completed herbal pill is totally made of herbs. It is natural, without any side effects. Due to the prostate's sensibility, it is important to bring no side effect to prostate. And the herbal pill has the effect indeed.
In summary, Dr. Lee says, according to the explanations above, it is obvious that the herbal therapy like it is better for treating BPH.
lester90053 zhangyolo
Posted
tom86211 lester90053
Posted
After much research I began taking Stinging Nettle Leaf capsules 480mg on 9/29/15 and since then I have noticed a real improvement in my BPH symptoms. I am taking 1 per day along with my morning vitamins. Before taking the capsules I was getting up every hour and a half at night, but now can last 3 and occasionally 4 hours. The urine flow was 75 ml max before and now it's double thatl, and I feel my bladder is not holding as much residual urine. Considering that the capsules are very inexpensive this experiement has gone very well. There is a study of Stinging Nettle for BPH from Iran on the net and the results were very good.
Tom
lester90053 tom86211
Posted
4 years ago I had green light laser. 9 months ago I had total retention again and had to catheterize 24/7. I took absolutely nothing for fhe prostate. One month ago, my system came back to normal again.
Can anyone explain this short of a miracle?
tom86211 lester90053
Posted
It's possible that you had a bladder stone that was blocking the flow, then the stone passed and you cleared. The normal explanations (infection and/or inflammation) don't explain the speed of recovery that you experienced.
In the past year I had three stones that passed and one was quite large. These can form in the kidneys or in the bladder due to retention. Just guessing here.
Don't think we'll ever know. I would be thankful for the miracle.
Tom
ramblin don30615
Posted
kenneth1955 ramblin
Posted
SalinTexas don30615
Posted
I just saw your post. I put my entire response in the other thread on PAE.
I had my PAE with Dr Sandeep Rao in El Paso Texas about 5 months ago. The first 2-3 months, my results varied with 1 day of needing to get up at night for every 4-5 days of improvement, but now I have no more problems peeing!
Dr Rao told me that since PAE is such a new procedure, there are no studies that have seen how patients have done beyond 3 years. But honestly, if my symptoms came back in a few years, the procedure I had done was so painless and quick that I wouldn't mind going back to him to have it done again.
-Sal
AndreUflackerMD don30615
Posted
My name is Andre Uflacker, MD, and I'm an Interventional Radiologist at the University of Virginia, in Charlottesvlle, VA. My colleague, Dr. Ziv Haskal, and I have just recently obtained the go-ahead from the FDA to conduct a trial of Prostatic Artery Embolization here at UVA, and because of the investigational and new nature of the procedure we feel like physician participation in these boards will be important.
To answer your question, we don't know for how long PAE will be effective with the current data. The largest trial to date is by Prof. Pisco from Lisbon who reported 255 cases, with sustainable results at around 2 years, with that particular trial mentioning a 72% rate of clinical improvement at 36 months. However, most patients that were followed were followed for less time than that, with the majority of patients having follow up at 12 months or less. There is new data constantly coming out about PAE, and the field is evolving rapidly, so more data is necessary for us to ensure the results are indeed sustained years after the procedure. There are systematic reviews of the published literature on PAE (probably what some members of the forum were referring to earlier), but this is not high level evidence as a true statistical analysis could not made on these data.
That said, we urge men to participate in clinical trials, as this will not only provide important data for future patients, but will also ensure that you as a patient obtain close follow up within a structured protocol that will maximize your safety while undergoing this "new" procedure. Yes, there are more visits, and it is more work for you as a patient in a trial, but at this stage, we feel that PAE should be performed in a controlled, closely monitored setting that a only a clinical trial can provide.
We encourage you to ask your Urologist questions and bring out concerns that you or anyone else may have regarding BPH and your options as well, so all alternatives are presented to you.
Here at UVA, we have extensive combined experience with Angiography and Embolization, and our trial, which is being done in partnership with the Dept. of Urology, is open for enrollment. A link to our trial is given below.
https://clinicaltrials.gov/ct2/show/NCT02592473
Please do not hesitate to ask us questions.
Good luck in your search for a treatment that works for you.
All the best,
Andre Uflacker, MD
kenneth1955 AndreUflackerMD
Posted
AndreUflackerMD kenneth1955
Posted
I'm glad to hear your uro-lift procedure worked well for you. We are happy to help and answer what questions we can.
Regards,
AU
nealpros AndreUflackerMD
Posted
Thanks so much for taking the time to participate in this blog. We really need expert input to our discussion.
I understand that it will be very useful to continue to pursue long term studies of the PAE. For example, it is important to understand if there are long term negative consequences of the procedure that haven't been seen yet. That said, I would urge to work with the FDA to insure that the procedure be approved by them even if it turns out that the positive effects only last a few years, and must then be repeated. There are many such procedures and medications which must be repeated to maintain continuous positive effects. It is even necessary for us to periodically cut our toe nails. We cut them, and the damn things keep growing. The PAE is such a benign procedure, particularly when compared with the alternatives, and seems to be so effective, that it shouldn't be killed just because it might be temporary.
Thanks again for your time and interest,
Neal
kenneth1955 AndreUflackerMD
Posted
ramblin kenneth1955
Posted
kenneth1955 ramblin
Posted
AndreUflackerMD kenneth1955
Posted
From what we can tell so far, men who undergo PAE do retain their ability to ejaculate. Intiuitively, embolizing the blood flow to the prostate should not alter the anatomy to affect ejaculation, HOWEVER, this is precisely why we should be performing these procedures as part of a clinical trial, b/c this could not be the case.
rom the available literature, erectile and sexual functions return to baseline after 12 months from PAE. It may very well be what ramblin was talking about below.
ramblin, I would encourage you to report your symptoms that you posted here to your physician who performed the PAE. If you are in a clinical trial, it would be important to know that you experienced retrograde ejaculation with PAE, as it has NOT been reported in any of the clinical studies out there.
The FDA has been very helpful in setting up our trial. Their priority is to ensure the safety of the public. Our trial here at UVA is intended to first test the safety of PAE and its efficacy. As far as FDA approval of the procedure, that will take time, but things are looking promising.
Thanks for the comments.
Regards,
AU
ramblin AndreUflackerMD
Posted
kenneth1955 AndreUflackerMD
Posted
Howard31850 AndreUflackerMD
Posted
Could you please explain how the necrotic tissue created from the PAE procedure is absorbed into the body? I read once that the inflammation which surrounds necrosis prevents phagocytosis from taking place so usually necrotic tissue has to be surgically removed or debrided to prevent accumulation of dead tissue. Thank you.