possible new statin??
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hello, if you remember my statin was stopped due to abnormal liver enzyme results in repeated blood tests, also a muscle thingy going on. update is that the liver ultra sound showed slight increase in size, also slightly fatty, but no cancers, my doctor suddenly decided that the onset of abnormal blood tests coincided with me taking Fluoxetine, firstly at 20mg, then up to 40mg daily, have stopped them altogether as of Monday, so am praying next blood test shows improvement of the enzymes. he also said if they did improve he wanted me to start 5mg of Rostuvastatin I think it's called, from 40mg of Simvastatin, to 20mg Atorvastatin, to only 5mg of this thing, how does that work then??
0 likes, 24 replies
lisa09924 david_25160
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loxie lisa09924
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jude65855 david_25160
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david_25160 jude65855
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jude65855 david_25160
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lisa09924 david_25160
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david_25160 lisa09924
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sonya10 david_25160
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with that in mind I'd be very wary of taking statins with any liver problem. If you stop Fuoxetine to improve liver then you do open door for statins to continue where Fluoxetine left off.
mrbob84 david_25160
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My question would be: is that because rosuvastatin is simply a more powerful statin, hence the side effects would stay the same, or is the reduced dosage of rosuvastatin going to acheive what simvistatin does in terms of lowering cholesterol while reducing the statin side effects by 8:1 in the case of simv and 4:1 in the case of atorv? The fellow cardiologist in my primary's office is thinking going onto rosuvastatin will remedy my memory losses that proliferate when on the statins.
I will say that my memory is better on the atorvastatin at 20 mg than it was when on the simvistatin at 40mg. But I still cannot find my jacket - with lots of valuables in it - that disappeared a few weeks ago just after our trip from CA to Oregon and back, and while on simvistatin I lost my took kit, which I had exotic tools in that I had collected over a 10 year period. It just vanished. And not from being in existence, I am sure. From my mind. From my memory of where I last used it and where I put it.
I will start the resuvastatin and see how it goes, but I still do not trust any statins, based on what's being said here. Has anyone here had any experience on memory issues with resuvastatin? Or cessation of other problems because of going from simv to rosuv? Anyone have stats on how much your cholersterol was reduced by taking any of the statins? My last lipids panel was after having been off the simv for a year, and since I then went onto atorv and have been on it for a couple of months - since Feb 18 2015 to be exact, going from 40mg to 20mg about half way thru that 2 month period - I want another lipid panel before going off them all, just to see the changes the statins made in the last 2 months of being on them.
sonya10 david_25160
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Simvastatin time of effect is 3 hours, so usually patients advised to take a at bedtime, basically same time every day. Its bioavailability is estimated to be around 5% and its excreted mostly through fecal output.
Rosuvastatin time of effect is much longer 19 hours yet it's bioavailability is higher at 20% and it is excreted through urine.
Rosuvasatin can be taken anytime of day, with or without food.
Simvasatatin is the most popular statin as its the cheapest, Rosuvastatin however is one of the most expensive to prescribe and is not usually offered initially upon starting statins, only if other statins cause a problem.
So basically both of the above fall under the statin drug group.
mrbob84 sonya10
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david_25160 sonya10
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sonya10 david_25160
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reggyside david_25160
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loxie reggyside
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sonya10 reggyside
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i do believe there is a link but doubt the medical profession have even considered it.
sonya10
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lisa09924 sonya10
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lisa09924 reggyside
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loxie sonya10
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