Side effects please help!

Posted , 6 users are following.

Hi, I have been on venlafaxine a total of 8 weeks. 2 weeks 75mgs, 2 weeks 150mgs and 4 weeks 225mgs. I am still feeling tired and have constant headaches/ head tension. It’s helped with my anxiety and depression a little but the tierdness and headaches are making me feel low. I spend a lot of time laying down and doing nothing as I feel unwell with these symptoms. Paracetamol doesn’t seem to help and I keep drinking water but it makes no difference. I do feel that if the tiredness and headaches went I would actually feel better. I guess my question is should I give it longer? I’m seeing pysch soon and unsure if I should change or give the venlafaxine more time for these symptoms/side effects to go. Has anyone else experienced this or needed longer than 4 weeks on a dose increase to feel relief? 

0 likes, 34 replies

Report

34 Replies

Next
  • Posted

    Hi. I'm sorry that you feel so poorly. It's tough to have patience waiting for these types of medications to work. All in all, you transitioned to higher doses quite quickly in 8 weeks, and typically, 4-6 weeks is what it takes in average for these medications to work. So I'd say you're halfway in. The headaches are a side effect for some people, so is tiredness. Even stomach upset. It's just symptoms of your body adjusting to the medication.

    I know it's hard to do, but try and do something aerobic today or the next few days.... Like waking, or cutting the grass, biking.... Anything that will burn off some of that stored up energy that can make you restless.

    I've been on 75 mg for many years, but had a life event that took my anxiety to a level that's unbearable. Can sleep, can't think, eat or much anything else. I saw my doctor yesterday and she upped me to 150. So the waiting game started today....I need it to work!

    Good luck and God bless you.

    Report Reply
    • Posted

      How are you getting on with your increase? Thankyou for your message and your right I guess I did increase fairly quickly. I spoke to my pysch who said to give it couple more weeks to see if the side effects improve. It’s just not nice feeling side effects as well as being depressed! 
      Report Reply
  • Posted

    Hi. I'm sorry that you feel so poorly. It's tough to have patience waiting for these types of medications to work. All in all, you transitioned to higher doses quite quickly in 8 weeks, and typically, 4-6 weeks is what it takes in average for these medications to work. So I'd say you're halfway in. The headaches are a side effect for some people, so is tiredness. Even stomach upset. It's just symptoms of your body adjusting to the medication.

    I know it's hard to do, but try and do something aerobic today or the next few days.... Like waking, or cutting the grass, biking.... Anything that will burn off some of that stored up energy that can make you restless.

    I've been on 75 mg for many years, but had a life event that took my anxiety to a level that's unbearable. Can sleep, can't think, eat or much anything else. I saw my doctor yesterday and she upped me to 150. So the waiting game started today....I need it to work!

    Good luck and God bless you.

    Report Reply
  • Posted

    Hello vicki, i revently did a much slower increase to arrive at 225mg. 10 weeks just to get to 225. I didnt have any side effects. You have increased quite quickly, never giving each increase time for things to settle down. Now that you have been on 225mg, you have to give it at least another 4 weeks for things to settle down. Ven is a really good snri, so you want to give it every chance. Although i didnt have side effects, ven didnt start working for me, noticeably working, for about 10 weeks. Now that it is, its probably the best ad ive been on. Just give it longer, as you have only been on a settled/constant dose for 4 weeks.
    Report Reply
    • Posted

      Thankyou for your reply. I understand what your saying it may tAke longer for me but do you think it’s a bit worrying I have these intense side effects at 4 weeks after increase? I thought side effects were supposed to go after 2-3 weeks. 
      Report Reply
    • Posted

      Nigel can I ask u a question u seem t9o know much more than me. I've seen people writing and you about snri and other letters wat does this mean. I'm now on velaflaxine. I've been on mitrazapine and citalopram are there's all the same snri you talk about just wondering x

      Report Reply
    • Posted

      Sure. There are different types of groups of anti depressants that are made out of different chemicals, and act in different ways to each other. The actual medications fall into one of these 8 or so groups. Ssris are one group/type of anti depressant that work in a certain way. Snris are another group that are similar, but work in a slightly different way. Mirtxapine is in a group of its own. Then there are older groups of anti depressants such as tricyclics and maoi's. Different groups suit different people. Nowadays, most people start on a ssri. These include zoloft, fluoxeteine and citalopram, and others. If they work for you great, as side effects are less than other types. If you have tried 2 or 3 ssris, and they havent worked, theres little point in trying any of the other ssris, as ssris arent suitable, or dont work for you. Then you go onto the next 2 groups, snris and mirtazapine. These 2 work differently to ssris. They both have low side effects and are good, and are tried when ssris dont work. There are some other groups with these 2. These are regarded as stage or tier 2 anti depressants. Venlafaxine is a snri. Stage 2 anti depressants are for more resistant anxiety or depression. If stage or tier 2s dont work, then combinations of different ones can be used. If none of these work, then the older type antidepressants, with more side effects can be used. Youve tried cit, mirt and ven. So a first and second tier ones. There would be little point in you trying a ssri again, although some people do with success. Its a question of trying different ones, until you find one that works. Cit is regarded as brst ssri, and ven best snri. Ven can be combined with a small amount of mirt. This combination makes each other work better, than what they do on their own. Hope it helps.

      Report Reply
    • Posted

      Thanks thats so helpful. I was in citalopram for over 10 years and it worked fab at the time. Then they added mitrazapine and I was never right on that but doctors thought maybe upping the dose would help but it never really did anything other than me putting on over 2 stone in 10 months. So I came off mitrazapine then that's when my problems all started it was hell. But I'm getting better mental health was called it n now I'm on venlafaxine 75mg twice a day n feeling much better. What do u think of this venlafaxine xx

      Report Reply
    • Posted

      Karen, i really like venlafaxine. I was in such a state from january to june, after a disaster trying citalopram. Its really pulled me back from complete misery. Took a long time to get going, and needed several dose increases. Despite time its taken, it always felt right, as no side effects, and

      as its immediate release, i felt sort of dreamy about a hour aftef taking it. Id say i started gradually feeling better from 187mg onwards, which i started about 9 weeks ago. Such a transformation in last 9 weeks, and im still improving. Ive been on 225mg for last 7 weeks. Getting to 187mg took about 8 weeks, from initial 37.5mg. Those first 8 weeks were grim, as id got into such a state from citalopram. Still early for you, as you can see how long its taken for me. Keep at it. If you do as well, you will be satisfied with it.

      Report Reply
    • Posted

      Hi Nigel, when you say the first 8 weeks were grim what do you mean with side effects or with depression? I’m 9 weeks in total and 5 weeks on 225mgs. I’m still depressed. Anxiety has improved but I have no energy, No motivation, tired and I ache. Just keep lying around feeling sorry for myself. As I increased quickly to 225mgs do you think there is still chance it could work? I’m starting to worry. Thanks 
      Report Reply
    • Posted

      During my first 10 weeks on ven, i wouldnt get out of bed at weekends, and would take me 3 hours or so to get up during the week. I had no interest in doing anything. Couldnt watch tv, speak to friends or family, and couldnt read. Everything was just too upsetting. Even after i started improving, still wasnt interested in much. I stayed stayed with my parents for the weekend 7 weeks ago and didnt enjoy any of it, and wasnt interested in talking to them. Stayed with them 4 weeks later, and it was completely different and back to normal. It took ages to start to work, when i did start to improve, it was very slowly for about 3 weeks, then improvements snowballed. This puts your time line and situation into perspective. Took 10 weeks on ven, just to be able to get up on a weekend.

      Report Reply

Join this discussion or start a new one?

New discussion Reply

Report as inappropriate

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up