Spontaneous purpura on methylprednisolone 1.5 mg

It is a side effect of all corticosteroids. You might be better on prednisone but there is no guarantee. The same applies to your hair loss.

Everyone responds to steroids differently and also a single person may respond differently to the various corticosteroids. I had awful side effects with methylpred (black beard, weight gain, developed Cushing's syndrome, severe myopathy) - I had none with prednisolone and have none with prednisone in the form of Lodotra/Rayos. Hair loss is the same. My hair turned into a Brillo pad with methylpred and stopped growing, it didn't fall out though. My hairdresser today commented "you have far too much hair!" - and that is after a month on methotrexate which caused some hair loss! I went through a period of permanent bad hair days - but it is back to normal, is growing and thick shiny and just a tad curly.

I'm afraid there is no-one here qualified to give an opinion about the gene expression and metabolising corticosteroids - we are all patients.

I did not lose hair; it got frizzy and curled. I do have the easy bruising with red spots. 

I wonder if my high intake Vit D3 ,with my doctors assent, has helped the hair because it's not falling out.

Jeannae, I am bald my dad was bald taking Prednisone has made a bad condition worse, what ever I have left is so fine it's hard to see just one strand. Bad joke time, my dad told me want to safe your hair catch it in a cigar box. But all kidding aside, on Pred I am leading a pretty normal PMR pain free life.. Think positive and trying to smile. ??

I take Vit K2 to help my bones absorb calcium and my pharmacist told me that it also helps to stop that subcutaneous bleeding.  I don't have any, maybe that's why.