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I took 5mg of amlodipine without problems for about a month. After the first-week period of adjustment, in which it completely knocked me out, I felt normal again and was overjoyed that it lowered and kept my usual 150+/90+ BP down to a textbook 120/80 (with minor variation).
But then side effects began to develop. I found my sleep increasingly poor, until I could only reach a half-sleep, no matter how much exercise I had had that day (or benadryls or Ambiens I took), "twilight sleep" I think it's called, and I arose as tired as when I went to bed, as if I hadn't slept at all.
Then I noticed that I would suddenly have shoulder and upper back muscle pain within an hour of taking amlodipine. The doctor lowered my dose to 2.5mg of amlodipine plus 40mg of benazepril, which brought only temporary improvement. The painful muscle spasms returned.
And most disturbing were the severe hot flashes that woke me up at night, as if the room were on fire, but the thermometer indicated it was only about 70°F (21°C) and my own body temperature was sub-normal, only 97 F or so (36 C), but despite my feelings of being overheated, I did not sweat - except from the soles of my feet, which is unusual for me. But my skin felt like it was on fire.
Then I would often wake with my brain "on fire" and itching like a bad allergy that I couldn't get to to scratch, and my eyes burning and streaming with tears.
The end of the amlodipine is when I opened the trunk (boot) of my car and blood vessels in the tips of my fingers where they had contacted the edge of the trunk (boot) lid burst and my fingers swelled up. I have never had weak blood vessels, or anything like that happen before.
Calcium blockers cause the blood vessels to relax and thin out - and now I wonder if not become weak. That would be a great setup for a stroke. I basically had a stroke in my fingers.
I will NEVER take this medication again. I believe it can lead to muscle pain, unrestorative interrupted sleep, and worse, strokes. I now consider it poison for me.
By the way, amlodipine has been banned in the Netherlands and other countries because its dangerous negative side effects outweigh its benefits. I don't think the Dutch are arbitrary or capricious in their decisions - I totally agree. This substance should be banned everywhere.
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