which brand of mirtazapine works best

Edited , 12 users are following.

I’ve been on Mirtazapine for about a year, take 45mg. It doesn’t seem to work as well as it first did. I also have epilepsy and take two med for it and had break through seizures recently. I can only afford the generics, the name brands cost $1300/mo. I looked through the web and found people complain about which generic manufactures people complained about and which ones they liked or non of the above compared to the real stuff. I’m going to my Dr. today and ask him to wrote down which generic manufacture I want me to take my prescription refill. Apparently all generics are not the same.

So the question is has anyone experienced or noticed the same thing with Mirtazapine manufactures. I haven’t kept track with which generic I’ve been taking. Currently the manufacture I am using is made by Aurobindo which I found out is made in India. People in the anti-seizure forums complained about India manufactures. I assume each generic also has to be different form other generics and India seems to be at the bottom of the list. Has anyone noticed who makes the generics you take and any difference?

0 likes, 19 replies

Report / Delete

19 Replies

Next
  • Posted

    Hi Steve,

    i take the generic on the mirt and have never taken the brand name so I can't compare the two. Since being on the generic I notice that I sometimes get a round redish pill and sometimes an oblongish one, and I have never noticed a difference but that's just me. It did kinda make me a little bit angry that my pharm would switch them up so often tho.

    i really hope you get this resolved as it could make a difference in your treatment.

     

    Report / Delete Reply
  • Posted

    Hi there.  I dont take Mirtazapine any more, but i do tale Zopiclone for sleeping.  I have noticed recently that chemists are dishing out generic brands as opposed to the original Sanofi brand i have had for many years and which were good.  The generics brands definitely do not work the same as i have recently discovered.  I think that probably goes for the Mirts as well. It all comes down to cost.
    Report / Delete Reply
  • Edited

    Im a chemist. I see these all the time. Generic or name brand ....ITS THE SAME ACTIVE INGREDIENT. THERE IS NO DIFFERENCE AT ALL. CHEMICALLY IT IS NOT POSSIBLE. Buy generic.
    Report / Delete Reply
    • Posted

      Well, how can it be that certain brands induce sleep (Mirtazapine) and others don't?  My first prescription worked wonders but subsequent scripts  were no good for sleep.  Unfortunately I didn't note the brand of the first prescription and have tried one after the other since but none make me sleepy 
      Report / Delete Reply
    • Posted

      Since posting this comment a year ago, I’ve looked up the main difference between generics and brand name meds. on the web. The main difference I found were the time release binders that hold and dispense the active med into the body. Although the patent on a drug runs out and generic makers are allowed make them, the patent on the time release binders never expires. Each generic maker has to develop their own time release binders. So even each generic drug manufacture have to develop time release binders that can’t be copied by another generic maker. Most of the time release binders made by generic manufactures seem to be inferior to the name brand. So one generic drug may release the active drug faster or slower vs another generic vs the brand name med. I also found out, that in the U.S., generic drug manufactures are given a latitude of containing +/- 20% of the active ingredient! Meaning the generic may contain a low of 80% to a high of 120% of the med.

      For my seizure drugs, the drug store would not honor the request of ordering the generic manufacture I requested. I found a drug store that carries the generic brand I wanted after doing a lot of research on the web of other people taking different generic anti-seizure meds. I switched ordering my meds to this drug store. I haven’t had any more auras since then.

      I live in the U.S. and our government FDA (Food and Drug Agency) started testing the quality of generic made drugs last year due to a high volume of complaints on meds. Generic seizure meds are near the top of the list to be tested. Most Dr’s, mine included, believe that there is no difference of any generic vs the name brand. They don’t take these drugs.

      I just got a new prescription refill of mirtazapine, 45 mg. The drug store switched generic makers. In the past, all of the pills were small. These pills are the size of a button. Only taken them for a few days but I’m falling asleep. Just to make sure these button size pills were actually mirtazapine, not a mistake by the pharmacy, I went to google and typed the in the name of the: manufacture (space) mirtazapine (space) 45mg (space) picture. The image and imprinted number showed up and matched. Seem to have a lot of fillers in this generic.

      Report / Delete Reply
    • Posted

      Thanks Steve for taking the trouble to come back.  Very interested in what you have said.  Indeed, the doctors don't take the drugs, therefore have no idea when it comes to the variable reactions regarding different brands.  I'm still at a loss as to what to do because I've now had three different brands since my first prescription, none of them induce sleep like the first brand, and as a consequence I'm struggling to rest at night.  Called the doctor and he said he was sorry to hear I was having this problem, and his solution was for me to take sleeping tablets as well!!!   I could kick myself for not keeping the box and making a note of the manufacturer.  Foolishly assumed I would automatically be given the same brand.  
      Report / Delete Reply
    • Posted

      Christine

      One more option you can try if you can recognize the picture of the box, you can also try googling mirtazapine (space) number of mg (15, 30, 45) (space) mg (space) package (space) pictures:

      Mirtazapine 30(whatever you take) mg package pictures.

      Maybe the package will be displayed and jar your memory. Hope that helps

      Report / Delete Reply
  • Posted

    Yes they all have the exact same ingredients .....the difference between the brand and generic comes down to quality control only...which means generics can be a little different ...hence the reduced price...
    Report / Delete Reply
    • Posted

      One med which doesn't matter the brand. I don't know why but with Lithium this does matter. I used to take Priadel and went to a different pharmacist where I was given a new brand. I had to return and ask for Priadel as previous. This is a reason for going to the same pharmacist. They will keep a record of your previous prescrips. If the GP makes a mistake or there is a query they will contact the surgery, or they will discuss it with you to ask you if there is a specific reason for the change.
      Report / Delete Reply
  • Posted

    hello i have taken mirtazapine for almost 15 years it works great generics are different the best brand is Teva but just recently the past year Teva discontinued mirtazapine I’m trying to get them to bring it back there’s very few that work right be careful of them anyone who wants to good drug get right to Teva pharmaceuticals on an email and try to get them to bring it back

    Report / Delete Reply
    • Posted

      unfortunately I have the same predicament with Teva discountinuing mirzatapine production. I called Teva directly and was told they stopped making it, it wasnt sold off to another company they just stopped so its gone for good. I used to take 7.5mg and would fall asleep like a log and feel good the next day, right now I have tried Apotex and the brand name form and unfortunately its not going great. have you tired any others and care to share your experience?

      Report / Delete Reply
    • Posted

      yes i called and emailed on there website to bring it back begging them im going to keep bothering them in the meantime I ordered brand name from Walmart and got it here it looks good but it didn’t work either found out it’s not the actual original brand the original brand comes from turkey I’m getting it through Canadian pharmacy the pill the 30 mg pill says or organon on one side and TZ5 on the other orange tablet i havent got it yet i will post how it works i havent slept good for few weeks but got good hopes this will work most good meds come from middle east over here they could care less all about money only people who need this stuff to work right is us that depend on it

      Report / Delete Reply
    • Posted

      I have been on generic Remeron since 11/2011 (and generic Lexapro). Until recently my sleeping was fairly good (8+ hours). But now the mirtazapine seems to give out after 5-6 hours. First thought is that the drug comes from a bad batch. Called the pharmacy and they looked up to see if either drug batch has been recalled; they said no. The Mirt maker is Citron, from the USA, and they appear to be a genuine company.

      Generic is around $30 while brand name from Merck is around $176.

      I'm starting to think that it might be worth the extra money, if I only knew that was the issue.

      Where are you in this?

      Report / Delete Reply
    • Posted

      hello actually very few brands work right I’m getting the brand name from Merrick over in USA doesn’t work you have to go to turkey through Northwest pharmacy out of Canada and get the Remeron pill that says orgnon on one side I’ve been getting it works great the only one I seen over here that works halfway decent is aurbindo and biconvex in the US

      Report / Delete Reply
    • Posted

      its brand name but made in turkey I go through Northwest pharmacy in Canada tell them you want brand name with organon on the one side and tz5 on oposite hope this helps only generic in US that worked for me was teva they stoped production

      Report / Delete Reply

Join this discussion or start a new one?

New discussion Reply

Report or request deletion

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up