Will my eyes ever improve

Hi Sophia, Did you put vit E cream on your lids? I have had a flare up and now the swelling has gone down my eye lids are so dry and crusty, I have been using vaseline and E 45 cream. Do you need a prescription for hydrocortisone cream,

Many thanks, Sarah

Hi Sophia,

I see that you had great results with the Doxycycline but this was 5 months ago.  I've just started taking them - one a day for a month & I'm on day 4.  I just wondered if you are still feeling much better?  

Many thanks :-)  

Dear Sophia,

The preservative, Benzalkonium Chloride, and others actually go into the eye. Eileen on this site got me to research preservatives. I found that the reason they are making preservative free eye drops is that they found out that using these preservative cause problems if used over a long period of time.

The wipes do not go in the eye. They are used only on the eyelas area. If some got into the eye you can wash with a rinse or put drops in to wash the eye.

I asked the doctor why they put the antibiotics in the eye when the problem was on the lash area. He told me some gets on the lashes.

There are other doctors who work at killing the Blepharitis on the lashes with an antibiotic. They call it an "off label use".

Here I thought I discovered something and low and behold it was known already.

You may want to look online like I did and find out about the preservatives. I had to get my dad preservative free as he uses steroids and I did not want to have him have a double dose of the preservatives.

Hope this info can help,

Lynda79

 

They are prescription Jo.

Jo  I forgot to mention do ask doctor about antibiotics like doxycycline if things don't improve.  I can't take them for other reasons but I know people do say they work well.  I would be interested to know how you get on with the Bicarb instead of baby shampoo.  Good luck and all the best.

Carol

Thank you Libralady and Linda and Janmin. Just been to Boots and got everything you have suggested except the Doxycycline for which I have to have a prescription and will start all of this when I get home tonight. i am very grateful for your advice, all of you, makes me feel less upset about it. Will post how I get on.

Good luck Jo. I think knowing that you are not the only one makes a huge difference. Do post your progress .

I have had a flare up this week and will be getting maxitrol today. Fingers crossed that I get the same results as last time!

Hi Lynda,

I'm curios as to what is the dental application that you found that has the doxycycline. I'm asking because coincidentally with the super flair up of blepharitis I had some aftas in my tongue, nothing dramatic but annoying enough. and it keeps happening I'm wondering if this might help and if I can get it or ask my dr. for it.

Thanks as always for all your goodwill research!

Dear Veronica,

Here it is:

 

Dental Information

Please note: Anaerobic includes staphylococcus species

 

1In vitro testing has shown that Porphyromonas gingivalis, Prevotella intermedia, Campylobacter rectus, and Fusobacterium nucleatum, which are associated with periodontal disease, are susceptible to doxycycline at concentrations ≤ 6.0 µg/mL.2 A single-center, single-blind, randomized, clinical study in 45 subjects with periodontal disease demonstrated that a single treatment with ATRIDOX® resulted in the reduction in the numbers of P. gingivalis, P. intermedia, C. rectus, F. nucleatum, Bacteroides forsythus, and E. corrodens in subgingival plaque samples. Levels of aerobic and anaerobic bacteria were also reduced after treatment with ATRIDOX®. The clinical significance of these findings, however, is not known. During these studies, no overgrowth of opportunistic organisms such as Gram-negative bacilli and yeast were observed. However, as with other antibiotic preparations, ATRIDOX® therapy may result in the overgrowth of nonsusceptible organisms including fungi. (See PRECAUTIONS)

Pharmacokinetics

In a clinical pharmacokinetic study, subjects were randomized to receive either ATRIDOX® covered with Coe-Pak™ periodontal dressing (n=13), ATRIDOX® covered with Octyldent™ periodontal adhesive (n=13), or oral doxycycline (n=5) (according to package dosing instructions). The doxycycline release characteristics in gingival crevicular fluid (GCF), saliva, and serum were evaluated.

Doxycycline levels in GCF peaked (~1,500 µg/mL and ~2000 µg/mL for Coe-Pak™ and Octyldent™ groups, respectively) 2 hours following treatment with ATRIDOX®. These levels remained above 1000 µg/mL through 18 hours, at which time the levels began to decline gradually. However, local levels of doxycycline remained well above the minimum inhibitory concentration (MIC90) for periodontal pathogens (≤ 6.0 µg/mL)2 through Day 7. In contrast, subjects receiving oral doxycycline had peak GCF levels of ~2.5 µg/mL at 12 hours following the initial oral dosing with levels declining to ~0.2 µg/mL by Day 7. High variability was observed for doxycycline levels in GCF for both oral and ATRIDOX® treatment groups.

 

What I got from this is that Doxycycline applied topically reduced the anaerobic bacteria (Staphylococcus Species) just like the wipes did.

 It took several months but the wipes did kill the Staphylococcus. Antibiotics may take less time judging from the dental application of Doxycycline.

For those who cannot use the wipes, this may be something to look into. A chemist or Dr. should be consulted as to the amount for the eye.

These wipes did not go into the eye. This antibiotic would not go into the eye. Just put on the eyelashes to kill the Staphylococcus (review of Ophthalmology on-line

If a patient has extremely mild meibomian gland disease, then hot soaks and scrubs are all she recommends. If patients have mild-to-moderate disease, she adds AzaSite rubbed into the lid margins twice a day, which is an off-label use. “Patients put one drop of AzaSite on one index finger, rub it between both index fingers, and then rub it on the four lid margins, where the eyelashes dive into the skin on the top of the eyelid wall,” she says.)

There are doctors like this one online who place the antibiotic on the eyelashes.There are other antibiotics that work in the same manner to disrupt the cell. I looked into Doxycycline as it works on Blepharitis internally. I took it and it did help Blepharitis.

Hope this info helps you.

Lyndaa79

 

 

 

 

Thanks Lynda!  I'll check with my dr/dentist.  I generally try to avoid antibiotics so I'm happy that the wetones seem to be working for me. I perfectly understand that this is an eyelid issue and I am using them on the skin around the eye and to the eyelid/eyelash margin.  It may be drying my skin a bit, but nothing more and for the first time in YEARS my eyelids are not reddish, I was so used to it that I thought it was like natural "eye shadow". I'm certain that perseverance and discipline, along with the miraculously precise formula of the wetones are working for me. I may try the topical antibiotic on my mouth if the aftas keep coming back, but other than that, I'm very grateful for this forum!

Take care,

Veronica 

Hi Lynda,

Started using the Wet Ones and it was like a miracle...my eyes improved dramatically after a month.  I have been bothered with blepharitits for years and for the first time I had hope.  Due to eye lid surgery, I did not use the Wet Ones for several weeks and the Bleph came back with a vengence.  I am back using them 4 times a day plus hot compresses and am gradually seeing improvement. I also shampoo my hair with Selsun Blue because someone said the bacteria can be on the scalp and travel to the eyelids.  Thank you for the information you shared in this forum.  It may not work for everyone, but it sure has for me.

Sandra

 

Thanks for taking so much time researching and then passing on this information.  I have a prescription for oral Doxycycline which I haven't yet collected - mainly because I'm worried about exacerbating a candida problem and also because I haven't seen information about anyone who used it and then didn't ever get blepharitis again.  My blepharitis hasn't caused any major problems for a long time - I religiously use eye wash with the same preservative as recommended by you in wet wipes.  Do you have evidence that the Doxycycline would get rid of blepharitis over the long term?  

Many thanks.

Dear  Haircrazydaisy,

I have found out that the preservatives, the same as in the wipes, actually cause problems when put in the eyes. Eileen, on this site, got me to research preservatives.

I found that it said using them over a long period of time can actually cause eye damage.

My dad uses steroids and they have preservatives in them so I switched to preservative free regular eye drops for lubrication to cut down on the amount he get. I use those now too. I was told by the doctor they can be used every half hour if I wanted to.

As for the doxycycline it did work for me on the blepharitis. I was on it for a month for another reason. I got cut by a can of beef dog food and started to get problems in my fingers. It was a run away bacterial infection.

The doctor said they do not know why it helps blepharitis.

I ended up eith Candida too. I take probiotics now and try to not do sugar. I need to get back to the diet. It is so hard.

I think the doxycycline would kill the Blepharitis if used on the eyelashes as I read a dental report that doxycycline used on the gums has a long lasting effect against staph.

You would need to go to a doctor on the amount. There are doctors online that mention using the antibiotics on the eyelash area. They call it "off label use". Guess I didn't discover that one. It is known.

It makes sense too. If these wipes can kill the staphylococcus on the eye area then an antibiotic can.

The doxycycline did not kill it even after a month so after that I found that a friend killed it topically and then I did it too.

If you are not allergic to shampoo etc. You may want to use the wipes before the meds with the candida problem.

If you decide to use the meds. I can suggest taking probiotics 2 hours after each pill to put some good back into you.

A doctor also told me to switch up the probiotics each month.

Hope this helps,

Lynda79

Thanks, Lynda, that's very useful :-)