wish me luck..losartan dose doubling tonight
Posted , 9 users are following.
After talking with the kidney doctor, he wants my blood pressure under 120 over 80. This morning it was 124 over 81. He requested I take 100 MG of losartan instead of 50 MG. He also asked me to take it right before bed time. I'm hoping I don't go to low. I take toprol Xl in the morning. Anyone who has been through doubling of the med and taking it at bedtime let me know if you have had issues with it.
0 likes, 61 replies
louise21984 todd70383
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I had to come off Losartan because I developed a cough. On Candersartan now.
todd70383
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I let the doctor know via email today. I'm sure he will tell me to stick with it.
MrsO-UK_Surrey todd70383
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I was taking both 50mg of Losartan together with Diltiazem but the latter was causing swollen ankles and a problem with my bowel so I've stopped it and continued just on the Losartan. However, it isn't controlling my blood pressure, so have to add another pill (a diuretic) shortly.
Many pills do cause vivid dreams and in fact I had a nightmare just the other night and woke up shaking!
Perhaps the exhaustion will improve as your body gets used to the higher dose - I do hope so, but do keep in touch and let us know what your doctor advises.
leslieadele todd70383
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louise21984 todd70383
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Hypertension is such a nuisance.
MrsO-UK_Surrey louise21984
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Soon after Losartan appeared on the market, the Stroke Association in its blurb on BP meds, commented that this drug does not have the side-effects associated with the other classes of drugs with the occasional exception of dizziness.
My pharmacist has recently backed up this comment by informing me that Losartan is the BP med of which he hears the least complaints of side effects from his customers. Certainly, in my experience, it is to date the only BP pill that is giving me no discernible side effects.....and I have tried 6 different pills in the last 18 months!
louise21984 MrsO-UK_Surrey
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One of my relatives is a primary care doctor, and she recommended Valsartan. It was fine, but then came off Patent and available was variable.
It's good that Losartan suits you.
I discussed Amlodipine with my doctor last week, and mentioned the side effects so many people have experienced. She said that some patients had none whatsoever.
Guess it just shows how individual we are. Some of my siblings are really overweight, and they don't have hypertension.
MrsO-UK_Surrey louise21984
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It's also true that there are some patients who are fine on Amlodipine - my hubby and a couple of close friends included. But this forum certainly seems to contain posts with many more complaints about Amlodipine than any other BP pill doesn't it. Certainly it proved a no-no for me with the unabiding side effect of swelling and inflammation in my lower legs and feet which even persisted after being in bed overnight, plus the inflammation eventually leading to a diagnosis of varicose eczema in the swollen areas.
I've also come across people for whom one brand of a med can be fine whereas the same med but produced by a different company can cause them problems.
As you say, we are individuals - what suits one may not suit another. I guess it depends on exactly what is causing each person's particular hypertension.
As far as the blurb is concerned, the manufacturers really do cover themselves when they quote that a particular pill can cause both constipation and diarrhoea. The Losartan blurb, for instance, describes the uses of Losartan, one of them being that it slows the decrease of kidney function in patients with high BP. Yet in another section it lists changes in kidney function, including kidney failure, as being "Common (1 in 10)!!! That is a subject on which my fingers and toes are tightly crossed!
Good luck with whatever treatment you are on just now.
louise21984 MrsO-UK_Surrey
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MrsO-UK_Surrey louise21984
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mike92384 MrsO-UK_Surrey
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I've had a previous sensitivity to the Amplodipine, necessitating me coming off that med..but I went back on it at the end of January/2014. About a week after taking the Amlodipine, that's when the burning began. My doctor all but insisted I persist. Now that Im complaing bitterly about the burning, he suggested I come off it...just to see if indeed this is the culprit, but my kidney specialist (Nephrologist) didn't want to change the meds when I saw him. This was at the initial consultation. He has ordered blood tests, which I've done, but don't see him for another 3 weeks. I'm hoping he finds something..or at least something minor which will help us get this bp under control. I intend on telling him about this burning..which is annoying the life out of me. It starts about 10 min. after I get up in the morning..starts at the top of my toes, then gradually works its way up my legs. After about 8 hrs. or so, my legs are on fire. I will certainly ask him about coming off the Amplodipine, but I must admit, I'm nervous of coming off for fear of the bp rising, unless he comes up with something else.
I'd certainly appreciate anything you might suggest in the meantime.
derek76 mike92384
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MrsO-UK_Surrey mike92384
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Losartan is the only pill that after many months doesn't seem to be producing any side effects, but when they add a second pill such as Diltiazem, my bowel is severely affected.
My consultant said that he has tried the drugs that are supposed to help my kidney function, however some have caused the opposite, especially Indapamide which produced several abnormal blood test results after just a few weeks, which I think even scared the consultant!
Do ask (demand!) to be tried on Losartan.
mike92384 MrsO-UK_Surrey
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I don't think it's asking a lot of the world for me to feel better.I can only hope that something is discovered or we have an answer in the next few weeks.
By the way, I was always instructed to rest for 5 min...put the bp cuff on my LEFT arm, sit with feet flat on the floor...then take the readings. I was told the very same when I saw the Nephrologist. Although he didn't say much, I could tell my the expression on his face, that what I was experiencing at the family Drs office was not the way to take bp readings. He even pointed to a poster he had on the wall & said "THAT is the correct way to take readings"..which is exactly how I was trained.
I'd appreciate further comments from you & I thank you in advance.
mike92384
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I don't see just why because of my age or condition, which I believe isn't the worst in the world why we can't get the bp down. Going on the old fashion medicines, i.e. Vasodilators, etc. seems weird to me...but we'll see.
derek76 mike92384
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Being a very 'sensitive' person most give me side effecst but Losartan only made me light headed until my system got used to it. One other effect is that I have a very slight itching sensation that my GP says is caused by an effect losartan has on the kidneys.
You should take your BP on the arm that consistsanly gives you the highest reading and it should be checked when sitting and standing. Both the specialist hypertension consultants I have been to did that.
MrsO-UK_Surrey mike92384
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According to my consultant, we should sit quietly for a couple of minutes before taking our blood pressure, on the left arm. We should then repeat the reading twice, each with a couple of minutes between, relaxing and letting our bodies go as much as possible. I then have to record the average of the 2nd and 3rd readings to take to my consultant.
And, yes, most of us can feel anxious when having blood pressure checked in the surgery/hospital, and with a lot of people that anxiety (white coat syndrome) can result in a higher than usual reading.
I've just been to the gym (GP referral) and am being an awkward gym bunny - the teacher takes our blood pressure at the start of the class and occasionally at the end after a few minutes cool down. Everyone without exception produces a lower reading after the cool down.......except that is yours truly.
I was getting quite excited over the last couple of weeks having seen some really good readings in the low 130's; however, that unfortunately doesn't seem to have lasted and it's going up again. Grrrr!
Do you want to share why you are under a nephrologist?
mike92384 MrsO-UK_Surrey
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It isn't that I fear Losartan..not at all. You're quite right in what you say about side effects with any/all medications. I'm just of the mindset that I'm not sure I could cope with being sick half the time anymore. Usually, it takes my body approximately 2 weeks to tell me if the meds are going to be accepted by my body or not. I may have to bite the bullet if the Nephrologist changes some of the meds, but at this point, I truly don't care..let's just get on with what the problem might be so I can start to feel like a regular human being again. Leslieadele has written that Losartan is the newer than the ACE class, but among the oldest in the ARB class...please read her post. I wouldn't say my bp readings are the worst in the world, but they're not mild either. Certainly, not readings that would require an emergency visit to hospital.
My pharmacist has told me that Amlodipine is not known for causing burning sensations...but a lot of threads I read dictate otherwise. For numbers 1 out of 100, doesn't necessarily mean anything, & again, I fully understand what derek is driving at. I know a few people who do take the Amlodipine & have no problems with it at all. Actually, I was beginning to wonder if I was some sort of rare breed for experiencing the burning, but the threads certainly indicate that I am NOT. The burning isn't painful..more like a sunburn..but extremely annoying..& more so since it's spreading.
I don't mind you asking why I will be seeing a Nephrologist. Sometimes something can be going on in the kidneys which keeps the bp elevated.
I had a CT scan..to check the overall condition of the kidneys, the structure, arteries, etc. This was over a month ago..haven't heard back, which goes to the old saying 'no news is good news". I had the bloodwork done 2 days ago, but the Lab doesn't let the patient know the results. The results are revealed when I see the Dr.
There are some days when I experience what I call an 'episode"...I go for several hours..the legs are burning although mildly. I start to feel slightly lightheaded..slightly nauseated..with a sleight weakish feeling in my arms...then it seems the burning becomes more intense. This feeling may last from 1-2 hrs...then I feel fine.
The Nephrologist told me the best way to take readings...is how I was trained...take 3 readings...throw the first one away, then average the next 2. He's asked me for readings..to take them 2x/day, 3 times/week..
but this was at the end of August, & my appt. isn't 'til Dec. 8. In no way does he need 400 readings! (exaggerating here of course! lol ). So, I'll begin taking the readings starting the first of next week. I won't be surprised if the readings are high, but I certainly will be telling him of my physical feelings (the episodes), & also the stress I've been under in my private life.
My friends are very supportive..which I appreciate so very much..but they are not experiencing what I'm going through, & don't understand a lot of it. I don't want to be talking to them about it a lot because of this,
yet they don't know how I'm feeling unless I tell them.
This is not all in the mind...what I'm experiencing is very real.
MrsO-UK_Surrey mike92384
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I also read an article produced by a hospital in the US carrying out research on Amlodipine, warning against prescribing it for women over a certain age because of a risk to their hearts. I queried this with one of my consultants some 18 months ago but he said it was never taken further. Once I read that it really put me off - 'no smoke without fire'.
At least you seem to being monitored well, with having kidney scan etc, so let's hope all is well there and you are simply being an awkward patient like me as far as BP drugs are concerned!
PS: I'm in the UK, just outside London.
derek76 mike92384
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The side effects were such that I pleaded to be taken off them. Of course it may just have been just one of them that caused the side effects. The next three prescribed caused other side effects that caused me try others.
mike92384 derek76
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When it comes to the appt with my Nephrologist, I too will plead to get off the Amlodipine. More & more I believe this drug to be the culprit of my burning legs & feet...& the spread of the fire.
mike92384 MrsO-UK_Surrey
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I'm glad for them, but the more I think of it, the more I believe this drug is the cause of my problems, unless there's something else going on in my system that we haven't discovered.
I know what you mean when you say "awkward patient" MrsO, but my body has always responded well to whatever medication may have been needed. Sure, there has been the odd time where I've needed just a little more medication to knock out whatever was making me sick, but I"ve never gone through this before in my life. As I've mentioned, & my family doctor has stated..I've taken bp meds in each of the classes...CC, ARB,ACE & Beta Blocker. I've got fingers crossed that the Nephrologist can come up with something, & we can find the right medication for me.
I hate to keep harping on the same thing, but I honestly do believe the Amlodipine is the villain. The more sites I read, the more I find people complaining about it. I went onto the Mayo Clinic site where it talks about Amlodipine..it lists side effects, etc. "Burning" IS listed although in the 'rare' category, but to me because it's rare, doesn't mean it doesn't happen. It has happened to you...to me...& several others.
derek76 mike92384
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MrsO-UK_Surrey derek76
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derek76 MrsO-UK_Surrey
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MrsO-UK_Surrey derek76
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derek76 MrsO-UK_Surrey
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Some years ago I had burst blood vessels in my eyes a nurse at the eye clinic said it was due to hypertnsion but my doctor at that time said no connection.
Presumably less blood should reduce the pressure. With the new reverseable BP treatment 'Rox flow coupler' on trial at the moment a device fitted in the groin diverts some blood flow from the heart to other areas. The hypertension specialist I am seeing said ' I see what it is doing but I don't understand why it works'
mike92384 MrsO-UK_Surrey
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With regard to the Amlodipine & my problem with it, or at least I STRONGLY suspect it's the problem..I find when I'm up for just only 5min or so, I can feel the heat starting on the top of my toes. I don't know if it's indeed the chemical in the Amlodipine starting to do its aggravating thing because it's certainly in the bloodstream, or it's the circulation of the blood along with the chemical. I think it's the latter...makes sense.
MrsO-UK_Surrey derek76
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Yes the jury is definitely out on whether or not high blood pressure is the cause for burst blood vessels in the eye - certainly my ophthalmologist at the time agreed that it might be the garlic in my case together with the steroids.
They admit they don't understand how most drugs work - I have a feeling that good old paracetamol might be one such drug if my memory serves me correctly.
MrsO-UK_Surrey mike92384
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The only way you are going to find an answer for your problem with 'heating' is to stop/replace the Amlodipine and see if this problem disappears.
mike92384 MrsO-UK_Surrey
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legs would be swollen quite a bit, but they're not swollen at all...just very very warm, or burning.
I fail to understand just why tests can't be run to find out...unless the only way is to come off the Amlodipine. I haven't heard from the Doctor's office as yet regarding an appt. for Ultrasound., so I'll put a call in very soon. I don't expect to hear anything about the Endocrinologist appt
for quite some time.
I do wonder though if I'll ever be able to feel human again.
MrsO-UK_Surrey mike92384
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derek76 MrsO-UK_Surrey
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mike92384 derek76
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mike92384 MrsO-UK_Surrey
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MrsO..I got a call from my Dr office on Friday...I managed to get the appt. for the ultrasound, but when I called to confirm that the appt. was suitable for me, the girl said she had a cancellation & was I interested in taking that appt...which is for Mon. Nov.24. Of course, I accepted with pleasure! So, I'll have the ultrasound done on my legs this morning. As for the appt. with the Endocrinologist...that takes place Dec. 2. I'm very pleased at getting these appts. so quickly. I was expecting a couple of months wait.
MrsO-UK_Surrey mike92384
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mike92384 MrsO-UK_Surrey
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MrsO-UK_Surrey mike92384
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mike92384 MrsO-UK_Surrey
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I haven't heard anything back form the Nephrologist's office as yet. The blood tests I had done were over a week ago, so I'm assuming "no news is good news"..but of course, I still have the appt. Dec. 8. It's in my mind though that if there were anything of great concern in the bloodwork, I'd have received a call by now rather than letting me wait a few weeks before the appt.
derek76 MrsO-UK_Surrey
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That nirse left and the new one doesn't do it. If fact each year it becomes more hurried.
MrsO-UK_Surrey mike92384
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mike92384 MrsO-UK_Surrey
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MrsO-UK_Surrey mike92384
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mike92384 MrsO-UK_Surrey
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It's fine for the medical profession or whoever to say that Amlodipine is not known for burning, but everyone's body is different. Look at the comments in this site..MANY are complaining of the same thing..burning, etc. The Mayo Clinic site lists one of the side effects of Amlodipine as burning...although listed in the 'rare' category. Because it's rare, doesn't mean it doesn't happen.
Something in the body causes burning...it's not natural.
derek76 mike92384
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Alternatively if you Google the Free Style Co-Pilot web site you can ask for a free one if you give the right answers they later make money from you having to buy lances and test strips after the samples run out.
mike92384 derek76
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I don't want to spend any money unnecessarily...my blood sugars have always been good, & about the only risk I have is that my late Mother was diabetic..that's about it.
jane6 louise21984
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louise21984 jane6
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jane6 louise21984
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