- recruitingTherapeutic confirmatory (Phase III)
Randomized controlled clinical trial on prophylactic treatment of constipation with polyethylene glycol with electrolytes in the critically ill child.
This study looks at whether giving a gentle laxative called Movicol to very sick children in hospital can stop them from getting constipated. Researchers want to see if starting this treatment early helps children pass stools more easily and comfortably while they recover.
Spain - recruitingNA
Balloon Inflation in Biofeedback
This study looks at a new way to treat ongoing constipation, especially when muscles don't work together properly. We're testing if inflating a small balloon during special exercises helps people learn to poo more easily compared to the usual method without a balloon. This could improve how we treat constipation.
United Kingdom - recruitingNA
Multi-strain Probiotic Effects on Self-Reported Constipation
This study looks into how a special mix of good bacteria, called probiotics, might help people with constipation. We want to see if these probiotics can make symptoms better and improve daily life for those struggling with digestive issues.
United Kingdom - recruitingNA
Pelvic Health Rehabilitation After Breast and Gynecologic Cancer
This study tests a new online program for women who've had breast or gynaecological cancer and have pelvic problems like bladder leaks or painful sex. It looks at how helpful and practical the program is, offering online sessions with a physiotherapist over 12 weeks.
Canada - recruitingNA
The ReVo Study: Low-volume vs High-volume Rectal Irrigation
This study compares two ways of using 'rectal irrigation' for long-term constipation. It aims to find out if one method (small volume or large volume) works better, is easier to use, and helps people with different constipation problems feel better.
United Kingdom - recruitingPHASE2
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
This study is testing a new medicine, brenipatide (LY3537031), for people with Irritable Bowel Syndrome with Constipation (IBS-C). We want to see if it's safe, what side effects it might have, and if it helps reduce symptoms.
United States · Belgium · Canada - active not recruitingNA
Validation of a Novel Functional Food Designed to Meet the Nutritional Needs of People Living With Parkinson's Disease
This study looks at a special drink for people with Parkinson's disease who have constipation. The drink contains helpful fibres and vitamins. Researchers want to see if it improves gut health and overall well-being over 12 weeks.
United Kingdom - recruitingNA
The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological Conditions
This study looks at how gut health, especially methane gas levels, might be linked to Parkinson's disease and memory problems. It also tests if a probiotic can help reduce methane. We want to understand if gut issues affect how these conditions develop and progress.
United Kingdom