- active not recruitingNA
Evaluation of Lifestyle Modification on Cardiovascular Risk
This study looks at how exercise, and a healthy Mediterranean diet, might help women aged 45-65 who are overweight or obese and have gone through menopause. It aims to improve heart health and metabolic health (like blood sugar and cholesterol) over 8 weeks.
United Kingdom - active not recruitingNA
Effect of Non-nutritive Sweeteners of High Sugar Sweetened Beverages on Metabolic Health and Gut Microbiome
This study looks at how different types of soft drinks – regular sugary ones, diet ones, and those sweetened with stevia – affect your health. Researchers want to understand if these drinks change the helpful bacteria in your gut and impact your body's metabolism over 10 weeks.
Canada - active not recruiting
Meta-Analyses of the Effect of Plant Protein Versus Animal Protein on Cardiometabolic Risk
This study looks at lots of past research to see if swapping animal protein for plant protein makes a difference to health conditions like diabetes, heart problems, and kidney issues. They want to understand if eating more plant-based protein, like from beans or nuts, can be better for our health.
Canada - active not recruitingNA
Effect of Raspberry on Gut Microbiota and Metabolic Syndrome
This study looks at how raspberry supplements might improve health by changing the tiny germs in our gut. We want to see if raspberries can help people struggling with weight and other related health issues by positively affecting their gut bacteria.
Canada - recruitingEARLY_PHASE1
Akkermansia Muciniphilia and Metabolic Side Effects of ADT
This study looks at whether apple cider vinegar can increase beneficial gut bacteria in men with prostate cancer starting hormone therapy. Researchers want to see if this helps reduce side effects like weight gain and diabetes, which can be linked to their treatment.
Canada - active not recruitingNA
WB-EMS Effects on Cardiometabolic Risk Factors
This study looks at how a type of exercise called whole-body electrical stimulation (WB-EMS) affects blood pressure and other health factors in men over 50. It wants to see if this quick, joint-friendly exercise can help people with slightly high blood pressure.
Germany - recruiting
Global Research Initiative for Patients Screening on MASH
This study aims to improve how doctors find serious liver conditions like MASH in people with health problems like diabetes or obesity. It brings together healthcare providers across Europe to use new care guidelines and raise awareness about these liver diseases.
Belgium · Czechia · France - not yet recruitingNA
Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 Diabetes
This study tests a new tool called the Snouda Metabolic Score to personalise Type 2 Diabetes treatment. It aims to see if tailoring diet, exercise, and supplements to individual metabolic needs can help people achieve remission.
United Kingdom - not yet recruitingNA
SCORE! Non-Physician Health Worker (NPHW) Implementation Protocol (SIP)
This study helps people in the SCORE! Cohort with high blood pressure, unhealthy cholesterol, or blood sugar issues. We're using trained health workers, not doctors, to support better health through lifestyle advice and check-ups over 12 months.
Canada - recruitingNA
Effects of Cranberry on Gut and Metabolic Health
This study looks at how cranberry drinks affect health in overweight people. We want to see if cranberries can help with blood sugar, fats, and gut bacteria. Participants will drink cranberry or a dummy drink for 12 weeks to see the effects.
Canada - active not recruitingPHASE3
Semaglutide 2.4 mg in Patients With Poor Weight-loss
This study is looking at whether a medicine called semaglutide, given as a 3mg injection, can help people who haven't lost enough weight after weight-loss surgery. It compares semaglutide to a dummy treatment over 68 weeks to see if it helps with weight loss and overall health.
United Kingdom - recruitingNA
Multi-organ Responses to CHronic Physical Activity and INactivity
This study looks at how physical activity and inactivity affect our bodies as we get older. We're trying to understand why staying active is so important for keeping healthy and preventing age-related problems, so we can help people live healthier for longer.
United Kingdom - not yet recruiting
Associations Between Dietary Patterns, LDL Aggregation, and Cardiometabolic Health: A Cross-sectional Analysis.
This study looks at how different diets (vegan, omnivore, carnivore) affect heart health. Researchers will see if certain diets make bad cholesterol clump together, which might lead to blocked arteries. It's for healthy adults following these diets.
United Kingdom - recruitingNA
Choroid Plexus Dysfunction in Neurological Diseases
This study looks into a problem called Cerebral Folate Deficiency (CFD) in a new condition called LHIPFOLD. Researchers think a part of the brain, the choroid plexus (CP), isn't working properly. They're using MRI scans and blood/fluid samples to find better ways to diagnose and treat this, which could help with other brain diseases too.
France - not yet recruitingNA
Comparative Effects of Carnivore and Mediterranean-style Diets on LDL Aggregation and Cardiometabolic Health
This study looks at how a Mediterranean or Carnivore diet affects heart health in people aged 30-60 with high cholesterol. Researchers will compare how these diets impact cholesterol and other heart markers over three weeks.
United Kingdom