Latest studies
- RecruitingPhase II
A study to learn if ZED1227 can improve continued celiac disease symptoms despite a gluten-free diet
This study is testing a new capsule called ZED1227 for adults with coeliac disease. Researchers want to see if this medicine can protect the gut and ease lingering tummy symptoms caused by accidental gluten exposure, even in people who already follow a strict gluten-free diet.
Coeliac diseaseItaly - RecruitingPhase I/II
A trial looking at different treatments for neuroblastoma which has come back after initial therapy
The BEACON2 trial is testing new combinations of cancer medicines for children and young people whose neuroblastoma has returned or worsened after initial treatment. The goal is to find out which drug combinations are safest and work best to control the disease and improve future care.
Relapsed NeuroblastomaItaly - RecruitingPhase III
A study of the anti-inflammatory medication colchicine for people with blocked arteries of the legs
Peripheral arterial disease (PAD) causes narrowed blood vessels in the legs. This clinical trial is testing whether an anti-inflammatory tablet called colchicine can help protect arteries and reduce the risk of serious complications, such as heart attacks, strokes, and leg amputations, in people living with PAD.
Peripheral artery diseaseItaly - CompletedPhase III
A randomized, open-label phase 3 study of amivantamab + FOLFIRI versus cetuximab/bevacizumab + FOLFIRI in participants with KRAS/NRAS and BRAF wildtype recurrent, unresectable or metastatic colorectal cancer who have received prior chemotherapy
This clinical trial is testing a new targeted drug, amivantamab, combined with chemotherapy for people with advanced bowel cancer. Researchers want to see if this combination works better at slowing cancer growth and helping people live longer than current standard targeted treatments after their first chemotherapy has stopped working.
Recurrent, unresectable or metastatic colorectal cancerItaly - RecruitingPhase IV
The 3TR-PARTNER-RA study: Are RNA signatures (biomarkers) in the tissue which surrounds the joints (synovial tissue) from patients with early Rheumatoid Arthritis (symptoms <12 months) predictive of response to biologic drug treatments?
This UK clinical study investigates whether testing a tiny sample of joint tissue can help doctors choose the most effective treatment for early rheumatoid arthritis. Researchers want to see if specific biological markers can predict whether a modern medicine called abatacept works well for newly diagnosed patients.
Rheumatoid arthritisItaly - CompletedPhase II
Testing new medicine for adults with Cystic Fibrosis who do not have access to the currently available CFTR-modulating drugs due to genetic mutations
This clinical trial tests a new three-in-one medicine for adults with cystic fibrosis who have rare genetic mutations. These patients cannot access currently approved treatments. Researchers are checking whether this daily combination of capsules can safely improve lung health after promising results in laboratory tests using patient cell samples.
Treatment of Cystic Fibrosis (CF) in patients with CFTR mutations who are responders in the organoid assayItaly - RecruitingPHASE2, PHASE3
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
This study looks at a new medicine called ponsegromab for advanced pancreatic cancer that has spread, especially when patients have lost a lot of weight and feel very tired. It aims to see if adding ponsegromab to standard chemotherapy helps more than chemotherapy alone.
CachexiaMetastatic Pancreatic Ductal AdenocarcinomaItaly - RecruitingPHASE3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
This study looks at a new medicine called enicepatide for people who are overweight or have obesity and also have type 2 diabetes. We want to see if it helps with weight loss and if it's safe to use.
Obesity or OverweightType 2 Diabetes MellitusItaly - RecruitingPHASE3
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
This study compares a new medicine, Elecoglipron, to an existing one, Semaglutide, for adults with Type 2 Diabetes. It aims to see if the new drug is safe and effective for people whose diabetes isn't well-controlled and who have a higher risk of heart problems.
Type 2 Diabetes MellitusItaly - RecruitingPHASE3
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
This study, called DLLEVATE, is looking at a new treatment, ZL-1310, for people with small cell lung cancer that has come back. It compares ZL-1310 to other standard treatments to see if it's safe and works well. You might be eligible if you're over 18 and have had previous treatments.
Small-cell Lung CancerItaly - RecruitingPHASE3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
This study is testing a new medicine, enicepatide, for people who are overweight or have obesity but do not have type 2 diabetes. It aims to see if the medicine helps with weight loss and if it's safe compared to a dummy medicine.
Obesity or OverweightItaly - RecruitingPHASE3
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
This study looks at a new drug, elritercept, for people with myelofibrosis and anaemia who are already taking ruxolitinib. It compares elritercept to a dummy drug (placebo) to see if it improves anaemia and other symptoms, and how safe it is.
MyelofibrosisAnemiaItaly - Completed
Vitamin D and lifestyle Intervention for gestational diabetes mellitus (GDM) prevention
This study looks at ways to prevent gestational diabetes, which is high blood sugar during pregnancy. Researchers are testing whether vitamin D supplements, healthy eating advice, regular physical activity, or combinations of these can help pregnant women with a higher body mass index stay healthy throughout their pregnancy.
Gestational diabetesItaly - CompletedPhase II
A two-part study to assess the effectiveness, safety, and blood levels of repeat doses of inhaled ETD001 in people with cystic fibrosis
This study looks at a new inhaled medicine called ETD001 for adults with cystic fibrosis. The treatment aims to loosen sticky lung mucus to help make breathing easier. Researchers want to see if the medicine is safe, well tolerated, and improves lung function when taken alongside usual daily care.
Cystic fibrosisItaly - Recruiting
Quality of Pediatric Resuscitation in a Multicenter Collaborative
This study looks at how the quality of CPR given to children during a cardiac arrest affects their recovery. Researchers are observing children in hospitals to see if better CPR techniques and after-care improve survival and brain function.
Cardiac ArrestCardiopulmonary ArrestItaly - RecruitingPHASE2
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
This study is testing a new medicine called belzutifan for certain types of advanced cancers, including rare adrenal gland, gut, and kidney cancers. We want to see how well it works and if it's safe for people aged 12 and over.
Pheochromocytoma/ParagangliomaPancreatic Neuroendocrine TumorVon Hippel-Lindau DiseaseAdvanced Gastrointestinal Stromal TumorItaly - RecruitingPHASE3
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
This study looks at a new treatment called AAA617 for men with early-stage prostate cancer that has spread a little (oligometastatic). It compares AAA617 to careful watching, to see if it can stop the cancer from growing and help men live better for longer.
Oligometastatic Prostate Cancer (OMPC)Italy - RecruitingPhase III
Tranexamic acid (and Desmopressin) for very early bleeds in the brain
This clinical trial tests whether an affordable medicine called tranexamic acid can stop bleeding in the brain after a stroke. Doctors want to see if giving this injection quickly in the emergency room helps people survive with less long-term disability, improving recovery and everyday life six months later.
Hyperacute primary intracerebral haemorrhage (stroke)Italy - RecruitingPhase III
Phase 3, randomised, double-blind, placebo- controlled, 3-arm study to investigate the safety and efficacy of efimosfermin alfa in participants with biopsy-confirmed F2- or F3-stage metabolic dysfunction-associated steatohepatitis (MASH) (ZENITH-1)
This clinical trial is testing a new injection called efimosfermin alfa for people with metabolic dysfunction-associated steatohepatitis (MASH), an inflamed fatty liver condition. Researchers want to see if monthly injections over four years can safely reduce liver fat, ease inflammation, and improve liver scarring compared to a dummy treatment.
Medical condition: Metabolic Dysfunction-Associated Steatohepatitis (MASH) Medical condition in lay language: Metabolic Fatty Liver Inflamation Therapeutic areas: Diseases [C] - Nutritional and Metabolic Diseases [C18]Italy - Completed
Evaluation of a dermocosmetic regimen for acne-prone skin in volunteers with mild, moderate or severe skin conditions
Acne is a common skin condition that affects confidence and well-being. This study tests whether a daily skincare routine using Eucerin products helps clear mild to severe spots. Researchers want to see how well these creams work over a year in people aged 12 to 50 across the UK and worldwide.
Subjects with acne-prone skin aged 12-50 years with Investigator's Global Assessment (IGA) grades 2-4, evaluating treatment of mild to severe acne vulgaris.Italy - RecruitingPhase III
A study of JNJ-78934804 in participants with moderately to severely active Crohn's disease
This clinical trial is testing a new combination medicine, JNJ-78934804, for moderate to severe Crohn’s disease. It combines two drugs into one injection to target gut inflammation. Researchers want to see if this two-in-one approach works better than a single medicine for people whose previous treatments have stopped working.
Crohn’s diseaseItaly - Not yet recruiting
Phase 3a and 3b update of the gastric cancer module, EORTC QLQ-STO22
Researchers are updating a widely used questionnaire that measures how stomach cancer and modern treatments affect daily life and well-being. If you have stomach cancer, you can help by completing the draft survey and sharing your feedback during a single, one-off chat lasting up to an hour.
Gastric adenocarcinomaItaly - RecruitingHuman Pharmacology (Phase I)- Other
A Phase 1, Open-Label, Multicenter Study of INCB160058 in Participants With Myeloproliferative Neoplasms.
This early-stage clinical trial is testing a new experimental medicine called INCB160058 for adults with myeloproliferative neoplasms (rare blood disorders). The main aim is to find out if the drug is safe, learn how the body handles it, and see what the best dose might be for future treatment.
Myeloproliferative NeoplasmsItaly - RecruitingTherapeutic exploratory (Phase II)
A Phase 2 Study to Investigate the Safety and Efficacy of Petosemtamab in Adults with Non-Small Cell Lung Cancer in Combination with Pembrolizumab.
This clinical trial is testing a new drug called petosemtamab combined with an established immunotherapy called pembrolizumab (Keytruda). It aims to find out if this combination is safe and effective at shrinking tumours in adults diagnosed with non-small cell lung cancer.
Non Small Cell Lung CancerItaly - RecruitingTherapeutic confirmatory (Phase III)
KontRASt-02: A randomized, controlled, open label, phase III study evaluating the efficacy and safety of JDQ443 versus docetaxel in previously treated subjects with locally advanced or metastatic KRAS G12C mutant non-small cell lung cancer.
This clinical trial compares a new targeted drug called JDQ443 with standard chemotherapy (docetaxel). It is for adults with advanced non-small cell lung cancer that carries a specific genetic change called KRAS G12C. Researchers want to find out which treatment keeps cancer from growing for longer.
Advanced non-small cell lung cancer harboring the KRAS G12C mutationItaly - CompletedPhase III
Prevention of complications to Improve outcome in elderly patients with acute stroke - A randomised clinical trial
This clinical trial looks at whether giving common medicines right after a stroke can prevent complications like fever, sickness, and chest infections before they start. Researchers want to see if treating older adults early with paracetamol, antibiotics, or anti-sickness medicine helps them recover better and stay independent.
Acute ischaemic stroke or intracerebral haemorrhageItaly - AuthorisedTherapeutic exploratory (Phase II)
A Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Safety, Tolerability, and Efficacy of TAK-360 for the Treatment of Narcolepsy with Cataplexy (Narcolepsy Type 1)
This clinical trial is testing an experimental medicine called TAK-360 for adults with narcolepsy type 1. Researchers want to see if the medicine is safe and helps reduce daytime sleepiness and sudden muscle weakness (cataplexy). Participants will receive either the study medicine or a dummy pill for comparison.
Narcolepsy with Cataplexy (NT1)Italy - AuthorisedTherapeutic use (Phase IV)
Sample Collection Study to Monitor the Risk of Malignancy Due to Insertional Oncogenesis in Early Onset Patients with Metachromatic Leukodystrophy Treated with OTL-200 in the Clinical Development Program
This study monitors the long-term safety of a gene therapy called Libmeldy in adults treated for metachromatic leukodystrophy (MLD). Doctors collect blood and tissue samples to check for very rare risks, such as abnormal cell growth or cancer, helping to ensure the treatment remains safe over time.
Metachromatic leukodystrophyItaly - AuthorisedTherapeutic confirmatory (Phase III)
SERENDIPITY: phase III multicentric randomized study assessing the reduction of chronic prostate inflammation with Permixon®
This clinical trial looks at whether a medicine called Permixon can help men with an enlarged prostate. Researchers want to see if calming prostate inflammation lowers the need for a repeat prostate biopsy within 12 months, while also checking urinary symptoms and overall prostate health.
Benign prostatic hypertrophyItaly - Completed
Implementing the concepts of mindfulness and community engagement to self-manage chronic diseases in four European cities
This study looks at a new community programme called SEFAC. It aims to help adults with long-term health issues, such as type 2 diabetes or heart disease. By combining mindfulness workshops, local community support, and a mobile app, it helps people build confidence and manage their health better day to day.
Citizens at risk of or has coronary heart disease and/or type 2 diabetes mellitusItaly - Completed
A multi-site observational study looking at the risk factors associated with tooth sensitivity, receding gums and tooth wear
This study looks into why adults develop sensitive teeth, receding gums, and worn tooth enamel. Researchers are studying how diet, brushing, and lifestyle affect oral health across Europe. Taking part is simple: it involves completing a short lifestyle survey and having a gentle mouth check-up during a single dental appointment.
Dentine hypersensitivity Tooth wear Recession Clinical loss of attachment Oral hygiene habits Dietary habitsItaly - AuthorisedTherapeutic confirmatory (Phase III)
A Phase 3 Multicenter Double-blind Randomized Study of Taletrectinib Versus Placebo in Patients With ROS1-Fusion Positive Stage IB-IIIA Non-Small Cell Lung Cancer Who Have Undergone Complete Tumor Resection
This clinical trial looks at whether a targeted medicine called taletrectinib can stop lung cancer from returning. It is for adults who have had surgery to completely remove non-small cell lung cancer with a specific gene change known as ROS1. Participants take either taletrectinib capsules or dummy capsules.
Non Small Cell Lung Cancer (NSCLC)Italy - AuthorisedTherapeutic confirmatory (Phase III)
A Long-term Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder for Treatment of Pulmonary Hypertension Associated with Interstitial Lung Disease
This study tests an inhaled dry powder medicine called treprostinil palmitil for adults with high blood pressure in the lungs linked to lung scarring. The trial lasts up to two years to see if the medicine is safe and helps improve breathing, walking ability, and overall quality of life.
Pulmonary Hypertension Associated with Interstitial Lung DiseaseItaly - AuthorisedTherapeutic confirmatory (Phase III)
AugmENtation witH cAnnabidiol iN first episode psyChosis: a doublE blind randomised controlled trial (STEP-ENHANCE Trial)
This clinical trial looks at whether cannabidiol (CBD) can help people experiencing psychosis for the first time. Participants take either CBD liquid or a harmless dummy medicine alongside their standard care for six weeks. Researchers want to see if adding CBD helps reduce symptoms and improves overall recovery.
First Episode Psychosis (FEP)Italy - AuthorisedTherapeutic exploratory (Phase II)
A Phase 2 Randomized, Double-blind, Placebo-Controlled Study to Assess the Safety and Efficacy of MTX-474 in the Treatment of Participants with Diffuse Cutaneous Systemic Sclerosis (dcSSc)
This study tests a new medicine called MTX-474 for adults with diffuse cutaneous systemic sclerosis. This rare condition causes skin thickening and hardening across the body. Researchers want to see if MTX-474 is safe and if it helps soften the skin over 24 weeks compared to a dummy treatment.
Diffuse Cutaneous Systemic Sclerosis (dcSSc)Italy - AuthorisedTherapeutic exploratory (Phase II)
A Phase 2, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Surovatamig in Adults with Antibody-mediated Kidney Disease
This study tests a new medicine called surovatamig for adults with kidney disease caused by the immune system. Doctors want to see if it is safe and can lower protein leaking into the urine, which helps protect kidney function. Everyone in the trial receives the active study medicine.
Antibody-mediated Kidney DiseaseItaly - RecruitingTherapeutic exploratory (Phase II)
A Phase IIb, randomised, double-blind, placebo-controlled, multicentre study to evaluate the efficacy and safety of concomitant use of eplontersen and ALXN2220 compared with eplontersen and placebo in adult participants with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM).
This clinical trial looks at whether combining two medicines, eplontersen and ALXN2220, is safe and effective for adults with a heart condition called ATTR-CM. Researchers want to find out if using both treatments together helps improve breathing, exercise fitness, and overall heart health better than taking eplontersen with a dummy drug.
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)Italy - AuthorisedTherapeutic exploratory (Phase II)
A Phase 2, open-label, randomized, dose optimization study evaluating the efficacy and safety of belantamab mafodotin administered in combination with cyclophosphamide, bortezomib, and dexamethasone in adult participants with newly diagnosed amyloid light chain amyloidosis (ALANIS)
This study is testing a new drug combination for people newly diagnosed with AL amyloidosis. Researchers want to see if adding a targeted medicine called belantamab mafodotin to standard treatments helps clear abnormal proteins from the blood, improves organ health, and works safely at the right dose.
newly diagnosed amyloid light chain amyloidosisItaly - AuthorisedTherapeutic confirmatory (Phase III)
A Phase 3b, Open-Label Study of Crinecerfont to Evaluate Androgen Reduction and Related Outcomes in Adults With Classic Congenital Adrenal Hyperplasia
This clinical trial is studying a medicine called crinecerfont for adults with classic congenital adrenal hyperplasia (CAH). CAH causes the body to make too much male hormone. Researchers want to see if this daily medicine can safely lower these hormone levels over 24 weeks without needing high steroid doses.
Classic Congenital Adrenal Hyperplasia (CAH)Italy - AuthorisedTherapeutic confirmatory (Phase III)
An Open-Label, Phase 3 Study to Evaluate the Efficacy and Safety of Salanersen (BIIB115) in Participants Aged 15-60 Years With Spinal Muscular Atrophy Who Are Either Treatment-Naïve or Have Previously Been Treated With Risdiplam
This phase 3 study tests an investigational medicine called salanersen (BIIB115) for people aged 15 to 60 with spinal muscular atrophy (SMA). Researchers want to see if it helps improve physical movement, arm strength, and walking ability over time in people new to treatment or previously treated with risdiplam.
Spinal Muscular AtrophyItaly - AuthorisedPhase III and phase IV (Integrated)
4TAZPower: A Phase 3b/4, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Trial to Evaluate the Efficacy and Safety of Daily Subcutaneous Injections of Elamipretide in Patients with Genetically Confirmed Barth Syndrome
This study tests whether a medicine called elamipretide can help men with Barth syndrome. Researchers want to see if daily injections under the skin can improve physical strength, walking ability, and day-to-day energy over 72 weeks, compared to an inactive dummy injection known as a placebo.
Barth SyndromeItaly - AuthorisedPhase I and Phase II (Integrated)- First administration to humans
Phase I/II Trial to Determine Safety and Efficacy of non-Viral Allogeneic Dual CD123/33-Chimeric Antigen Receptor CIK (CARCIK-CD123/33) Cells in Adult and Pediatric Patients with Relapse/Refractory Acute Myeloid Leukemia (AML) and Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
This clinical trial tests a new type of cell therapy for adults with hard-to-treat blood cancers, including acute myeloid leukaemia and BPDCN. Doctors want to see if specially modified donor immune cells are safe, find the right dose, and find out if they can help destroy stubborn cancer cells.
Acute myeloid leukemia and Blastic plasmacytoid dendritic cell neoplasmItaly - AuthorisedTherapeutic confirmatory (Phase III)
A Phase III, Multicentre, Randomised, Open-label Study to Compare the Efficacy and Safety of AZD0486 plus Rituximab versus Chemotherapy plus Rituximab in Previously Untreated Participants with Follicular Lymphoma (SOUNDTRACK-F1)
This phase 3 trial is testing a new targeted medicine called surovatamig (AZD0486) combined with rituximab for people newly diagnosed with follicular lymphoma. Researchers want to see if this new combination works better and is safer than standard chemotherapy combined with rituximab.
Follicular LymphomaItaly - AuthorisedHuman Pharmacology (Phase I)- First administration to humans
A First-in-Human Study of INCA035784 in Participants With Myeloproliferative Neoplasms
This early-stage clinical trial tests a new drug, INCA035784, in humans for the first time. It is for adults with myeloproliferative neoplasms (rare blood disorders where the body makes too many blood cells). Researchers want to find out if the medicine is safe and what dose works best.
Myeloproliferative NeoplasmsItaly - AuthorisedHuman Pharmacology (Phase I)- First administration to humans
A dose escalation and expansion study of XB010 as a single agent and combination therapy in subjects with locally advanced or metastatic solid tumors
This early-stage clinical trial is testing a new drug called XB010 in adults with advanced solid tumours. Researchers want to find out if the treatment is safe, discover the best dose, and see how well it works either on its own or alongside other cancer medicines.
Locally Advanced or Metastatic Solid TumorsItaly - AuthorisedTherapeutic confirmatory (Phase III)
Premedication with dexamethasone for preventing interstitial lung disease in patients with breast cancer treated with trastuzumab deruxtecan
This study looks at whether taking a common steroid tablet called dexamethasone can protect the lungs of people with breast cancer. It tests if the steroid helps prevent lung inflammation in patients receiving an effective cancer medicine called trastuzumab deruxtecan (T-DXd) over a 12-month period.
Breast CancerItaly - AuthorisedTherapeutic exploratory (Phase II)
A RANDOMIZED, PLACEBO-CONTROLLED, MULTICENTER, CLINICAL TRIAL OF COLCHICINE IN AMYOTROPHIC LATERAL SCLEROSIS (CO-ALS II)
This clinical trial is testing whether a medicine called colchicine can help slow down amyotrophic lateral sclerosis (ALS), a form of motor neurone disease. Adult participants will take either colchicine or a dummy tablet each day for 30 weeks, followed by 36 weeks where everyone receives the trial medicine.
AMYOTROPHIC LATERAL SCLEROSISItaly - AuthorisedTherapeutic exploratory (Phase II)
AN OPEN LABEL, SINGLE ARM, EXPLORATIVE TRIAL TO EVALUATE EFFICACY AND SAFETY OF BEROTRALSTAT IN PREVENTING ANGIOEDEMA ATTACKS IN SUBJECTS WITH ACQUIRED ANGIOEDEMA DUE TO C1 INHIBITOR DEFICIENCY (AAE)
This study looks at a daily tablet called Orladeyo for adults with acquired angioedema. This rare condition causes sudden, painful swelling attacks under the skin. Researchers want to find out whether taking this medicine for six months can safely reduce the number and severity of these swelling episodes.
Acquired angioedema due to C1 inhibitor deficiencyItaly - AuthorisedTherapeutic exploratory (Phase II)
Denosumab or Zoledronic acid for erosive hand osteoarthritis (EHOA) in patients with osteoporosis a randomized controlled trial (ZODIAC trial)
This clinical trial compares two bone-strengthening medicines, denosumab and zoledronic acid, in adults with both osteoporosis and erosive hand osteoarthritis. Researchers want to see which medicine is better at protecting finger joints from bone damage, easing joint pain, and improving everyday hand movement over a 12-month period.
Erosive hand osteoarthritis (EHOA)Italy - AuthorisedTherapeutic exploratory (Phase II)
A Phase 2, randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of CRD-4730 in patients with heart failure with reduced ejection fraction (HFREF) (CALIBRATE-HF)
This study is testing a new tablet called CRD-4730 for adults with heart failure. Researchers want to see if the medicine can help the heart pump blood better, ease everyday symptoms, and improve quality of life. Participants will take either the study drug or a dummy pill for 24 weeks.
heart failureItaly