Latest studies
- Recruiting
Severe Complications During Ventricular Tachycardia or Premature Ventricular Complex Ablation
This study looks back at information from hospitals to understand serious problems that can happen during or soon after a heart procedure called ablation for fast or extra heartbeats (VT/PVC). Researchers want to find out why these problems occur and how they were managed.
Ventricular Tachycardia (VT)Premature Ventricular ComplexesSlovenia - RecruitingPHASE2
Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
This study is testing a new medicine, Imeroprubart, for adults with a nerve condition called Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). Researchers want to see if it's safe and helps improve symptoms compared to a dummy treatment.
Chronic Inflammatory Demyelinating PolyneuropathySlovenia - Active not recruitingPHASE3
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
This study compares a new drug, Giredestrant, with standard hormone therapy for early breast cancer. It's for people with a specific type of breast cancer (ER-positive, HER2-negative) who have already had surgery.
Early Breast CancerSlovenia - Recruiting
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
This study looks at how well Medtronic heart devices, like pacemakers and defibrillators, perform over a long time. It helps ensure these devices are reliable and safe for people with heart conditions such as irregular heartbeats or heart failure.
ArrhythmiaBradycardiaHeart FailureSinus TachycardiaSlovenia - Active not recruitingPHASE3
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-2)
This study is looking at a new medicine called remibrutinib for people with relapsing multiple sclerosis (RMS). It compares remibrutinib to an existing medicine, teriflunomide, to see how well it works and if it's safe. It's a large study, involving about 800 people.
Relapsing Multiple SclerosisSlovenia - RecruitingPHASE3
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast
This study looks at a long-term treatment called nerandomilast for people with pulmonary fibrosis. It's for those who've used it in a past study. We'll see how safe and effective it is over time, checking if it helps lung function and slows down the disease.
Idiopathic Pulmonary FibrosisProgressive Pulmonary FibrosisSlovenia - RecruitingPHASE3
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
This study looks into a new treatment for adults with heart failure. It combines two medicines, vicadrostat and empagliflozin, to see if they can improve heart health in people with a specific type of heart failure. Participants take tablets daily and are closely monitored.
Heart FailureSlovenia - Active not recruitingPHASE3
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis
This study looks at how well a medicine called risankizumab works and how safe it is for people with ulcerative colitis. It's for those who have already shown improvement with this medicine in a previous study.
Ulcerative Colitis (UC)Slovenia - RecruitingPHASE3
A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
This study is looking into the long-term safety of a new medicine called dazodalibep for people with Sjögren's Syndrome. It involves individuals who have already taken part in previous studies of this medicine.
Sjögren's SyndromeSlovenia - Active not recruitingPHASE3
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
This study looks at a new medicine called ziltivekimab for people with heart failure and inflammation. It aims to see if monthly injections of ziltivekimab can help, compared to a dummy medicine, over a few years.
Heart FailureSlovenia - Active not recruitingPHASE3
A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
This study is testing a new medicine called lutikizumab for people aged 12 and over with moderate to severe hidradenitis suppurativa (HS). It compares the new medicine to a dummy treatment (placebo) to see if it helps reduce HS symptoms and is safe.
Hidradenitis SuppurativaSlovenia - Active not recruitingPHASE3
A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State
This study is looking at a new medicine called Dazodalibep for people with Sjögren's Syndrome. It aims to see how well it helps with symptoms and whether it's safe to use, especially for those with moderate to severe symptoms.
Sjögren's Syndrome (SS)Slovenia - Active not recruitingPHASE3
A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433
This study looks at a new medicine called upadacitinib for adults with Crohn's disease. It checks how well it works and if it's safe over a long time for people who have already started treatment in previous studies. The aim is to see if it can help manage Crohn's.
Crohn's DiseaseSlovenia - Ongoing, recruitingTherapeutic use (Phase IV)
An 18-month low-interventional prospective, multicentre study to assess joint outcomes in patients with haemophilia A or B on prophylaxis with efmoroctocog alfa or eftrenonacog alfa
This study looks at how well different medicines (Elcocta and Alprolix) help people with haemophilia A or B protect their joints. Researchers will follow participants for 18 months to see if these treatments prevent joint problems.
Hemophilia A and BSlovenia - Active not recruitingPHASE2
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease
This study is looking at a new combination treatment, JNJ-78934804, for people aged 18-65 with Crohn's disease that is moderate to severe. It compares this new treatment to existing medicines, guselkumab and golimumab, to see how well it works over 48 weeks.
Crohn's DiseaseSlovenia - Recruiting
Trifecta-Kidney cfDNA-MMDx Study
This study looks at new ways to check for rejection in kidney transplant patients. It compares a new blood test (DD-cfDNA) with a special biopsy test (MMDx) and traditional checks to see which is best at finding rejection accurately.
Kidney Transplant RejectionSlovenia - RecruitingPHASE2
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
This study looks at new medications for adults with moderate to severe Crohn's disease. Researchers want to see how well these 'targeted therapies' work and if they cause side effects, to find better ways to manage the condition.
Crohn's DiseaseSlovenia - Active not recruitingPHASE2
A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML
This study is testing a new combination of treatments for children and teenagers with a certain type of acute myeloid leukemia (FLT3-mutated AML). It combines a drug called midostaurin with standard chemotherapy to see if it's safe and effective for these patients.
FLT3-mutated Acute Myeloid LeukemiaSlovenia - RecruitingPHASE3
A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
This study is testing a new medicine, nipocalimab, to see if it can help prevent a serious blood condition called FNAIT in babies. FNAIT can cause low platelet counts in newborns, which can lead to bleeding problems. Researchers want to know if nipocalimab is effective and safe.
Thrombocytopenia, Neonatal AlloimmuneSlovenia - Recruiting
Defects of Keratinocytes Function in Dermatologic Patients
This study looks at a skin condition called hidradenitis suppurativa (HS). Researchers want to understand how tiny skin cells called keratinocytes work when someone has HS. They hope this will lead to better treatments for HS, an often painful and challenging long-term condition.
Hidradenitis SuppurativaSlovenia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A phase 3b open-label, multicenter study evaluating physical activity and joint health in previously treated patients ≥12 years of age with severe haemophilia A treated with intravenous recombinant coagulation factor VIII Fc-von Willebrand Factor-XTEN fusion protein (rFVIIIFc-VWF-XTEN; efanesoctocog alfa) for 24 months
This study is looking at a new treatment called efanesoctocog alfa for severe haemophilia A. It aims to see how it affects physical activity and joint health in patients aged 12 and over, comparing results over 24 months. It's a key step in understanding if this medicine helps people live more active lives.
Haemophilia ASlovenia - Active not recruiting
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
This study looks at how well certain eye medicines from Roche work for conditions like wet macular degeneration and diabetic eye disease in real patients. It's about understanding long-term results and why doctors choose specific treatments, without changing how patients are usually cared for.
Neovascular Age-related Macular DegenerationDiabetic Macular EdemaRetinal Vein OcclusionBranch Retinal Vein OcclusionSlovenia - RecruitingPHASE3
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
This study is testing a new medicine, Masitinib, for people with Motor Neurone Disease (ALS). It aims to see if Masitinib, when taken with the usual medicine Riluzole, can help slow down the disease compared to taking Riluzole with a dummy pill.
Amyotrophic Lateral SclerosisSlovenia - RecruitingPHASE3
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
This study is testing a new drug, giredestrant, against a standard treatment for advanced breast cancer. It's for people whose cancer has grown resistant to previous hormone therapy, to see if giredestrant, combined with other drugs, works better and is safe.
Estrogen Receptor-Positive, HER2-Negative Advanced Breast CancerSlovenia - Active not recruitingPHASE2
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
This study looks at new ways to treat ulcerative colitis, a condition causing gut inflammation. We're testing a combination of medicines (JNJ-78934804) for people whose current treatments aren't working well. The goal is to see if these new approaches are safe and effective.
Colitis, UlcerativeSlovenia - Enrolling by invitation
A Study Following Males With Haemophilia A on Prophylaxis With Esperoct®
This study looks at how well Esperoct® works and if it has side effects for men and boys with haemophilia A. Participants will receive their usual treatment and share information about their health over several years.
Haemophilia ASlovenia - Active not recruitingPHASE3
RT or No RT Following Chemotherapy in Treating Patients With Stage III/IV Hodgkin's Disease
This study looks at whether adding radiation after chemotherapy helps people with advanced Hodgkin's disease. Researchers want to see if this combination prevents the disease from coming back or helps people live longer, compared to chemotherapy alone.
LymphomaSlovenia - Active not recruitingPHASE3
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
This study is for children and young people under 25 with a type of brain tumour called low-grade glioma. It compares a new medicine, tovorafenib, with standard chemotherapy to see which works best and is safest for those needing first-time treatment.
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade GliomaSlovenia - RecruitingPHASE3
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
This study is testing a new medicine called elranatamab for people with a type of blood cancer called multiple myeloma. It's for those whose cancer has returned after other treatments. We want to see if elranatamab works better than standard medicines.
Multiple MyelomaSlovenia - RecruitingPHASE3
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
This study looks at a new medicine called mezagitamab for a kidney problem called IgA nephropathy. It compares mezagitamab to a dummy medicine to see if it lowers protein in the urine and helps protect kidneys. All adults over 18 with this condition can take part.
Kidney DiseaseSlovenia - Active not recruitingPHASE2
Frexalimab in Preservation of Endogenous Insulin Secretion Compared to Placebo in Adults, Adolescents and Children on Top of Insulin Therapy (FABULINUS)
This study looks at a new drug called frexalimab for people aged 12-35 newly diagnosed with Type 1 Diabetes. It aims to see if frexalimab, taken alongside insulin, can help the body keep making its own insulin. Half the participants will get frexalimab, and half a dummy medicine.
Type 1 Diabetes MellitusSlovenia - Not yet recruitingPHASE3
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020)
This study is looking at new ways to treat a type of childhood leukaemia called B-Cell Acute Lymphoblastic Leukaemia (ALL) when it comes back. It aims to use kinder, more targeted treatments instead of strong chemotherapy.
B-Cell Acute Lymphoblastic LeukaemiaSlovenia - RecruitingPHASE2
Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome
This study looks at a new medicine called osilodrostat (LCI699) for children and teenagers aged 2-17 with Cushing's syndrome. Researchers want to see how the medicine works in the body, its effects, and if it's safe. It's for those who have had surgery, are waiting for it, or can't have it right away.
Cushing SyndromeSlovenia - Not yet recruitingNA
Urinary Proteomics Combined With Home Blood Pressure Telemonitoring for Health Care Reform
This study looks at new ways to predict heart and kidney problems in people aged 55-75. It combines checking blood pressure at home with a urine test. Researchers want to see if this combination helps doctors treat and prevent these conditions more effectively and affordably.
Protein DeregulationBlood PressureHealth Care UtilizationCost EffectivenessSlovenia - Active not recruitingPHASE3
A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
This study looks at new drug combinations for advanced liver cancer that has already been treated. It compares atezolizumab with lenvatinib or sorafenib against lenvatinib or sorafenib alone, to see if the combinations work better and are safe.
Unresectable Hepatocellular CarcinomaSlovenia - RecruitingNA
LANDMARK Trial: a Randomised Controlled Trial of Myval THV
This study, called the LANDMARK Trial, is looking into how safe and effective a new heart valve called Myval THV is. It's compared to existing valves for people with a common heart condition called aortic valve stenosis. The goal is to see if it works just as well.
Aortic Valve StenosisSlovenia - Recruiting
SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access
This study, called SPECTA, collects information and samples from cancer patients to help scientists better understand cancer. It aims to improve how we diagnose and treat different types of cancer in the future by looking at many different aspects of the disease.
All Tumor TypesSlovenia - Active not recruitingPHASE3
Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)
This study compares a new medicine, ABP 692, with an existing one, Ocrevus, for people with a type of multiple sclerosis (RRMS). It checks if special brain scans and how the medicines act in the body are similar, aiming to offer another treatment option.
Relapsing-remitting Multiple Sclerosis (RRMS)Slovenia - Recruiting
PulseSelect™ PFA Global Registry
This study is observing how well a new treatment called PulseSelect™ PFA works for people with atrial fibrillation (an irregular heartbeat). It collects information on its safety and effectiveness in patients receiving this approved treatment as part of their routine care.
Atrial FibrillationSlovenia - Active not recruiting
DiamondTemp Global Registry
This study looks at how a treatment called DiamondTemp™ Ablation works for people with an irregular heartbeat (arrhythmia). Researchers are watching patients treated with this system in hospitals to see how well it works and if it's safe over at least 12 months.
ArrhythmiaSlovenia - Recruiting
European Registry on the Management of Helicobacter Pylori Infection
This study is gathering information from doctors across Europe about how they treat H. pylori infection. It aims to understand current practices, check if guidelines are followed, and see what treatments work best to help improve care for patients with this common stomach infection.
H. Pylori InfectionSlovenia - Active not recruitingPHASE2
A Study to Assess Adverse Events and Change in Disease Activity From Intravenous (IV) and Subcutaneous (SC) Lutikizumab in Adult Participants With Active Ulcerative Colitis
This study looks at a new medicine called lutikizumab for adults with moderate to severe ulcerative colitis. It aims to see if it's safe and how well it works compared to a common treatment called adalimumab.
Ulcerative ColitisSlovenia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase III, Double-Blinded, Multicenter, Randomized Study Evaluating the Efficacy and Safety of Neoadjuvant Treatment with Atezolizumab or Placebo in Combination with Platinum-Based Chemotherapy in Patients With resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer
This study is testing a new way to treat early-stage lung cancer before surgery. It combines standard chemotherapy with a new drug called Tecentriq, or a dummy drug, to see if it helps patients live longer and stay cancer-free.
Early-Stage Resectable Non-small cell lung cancer (NSCLC)Slovenia - Recruiting
REtroperitoneal SArcoma Registry: an International Prospective Initiative
This study aims to better understand a rare cancer called retroperitoneal sarcoma (RPS). Doctors are collecting information from patients having surgery for RPS to learn how to improve treatments and outcomes, as surgery is currently the main option.
Retroperitoneal SarcomaSlovenia - Active not recruitingPHASE3
Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma
This study looks at different chemotherapy treatments, with or without radiation, for Hodgkin's lymphoma. Researchers want to find the best way to treat this cancer, making sure treatments are effective while reducing side effects.
LymphomaSlovenia - Recruiting
E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe
The E²-RADIatE study is collecting information from cancer patients across Europe who are having radiotherapy. This helps researchers better understand how radiotherapy is used and how it works alongside other treatments to improve care for people with cancer.
CancerSlovenia - Recruiting
Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants
This study looks at how safe and effective clot-busting medicine (like Alteplase or Tenecteplase) is for people having a stroke who recently took certain blood thinners (DOACs). We want to see if it helps their recovery.
Ischemic StrokeSlovenia - RecruitingNA
Prehospital Resuscitation Intranasal Cooling Effectiveness Survival Study 2
This study looks at whether very early cooling, started by paramedics, can help people who have had a sudden heart stoppage outside of hospital. We want to see if it improves survival and brain recovery compared to keeping body temperature normal.
Out-Of-Hospital Cardiac ArrestHypothermiaVentricular FibrillationSlovenia - Active not recruitingPHASE3
A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria
This study looks at the long-term safety of a new medicine, PTC923, for people with Phenylketonuria (PKU). It also checks if the medicine helps people eat more varied foods by seeing if their usual diet and protein intake change over time.
PhenylketonuriaSlovenia - Ongoing, recruitingPhase II and Phase III (Integrated)
A Phase 2/3 Study of Navtemadlin as Maintenance Therapy in Subjects with TP53WT Advanced or Recurrent Endometrial Cancer Who Responded to Chemotherapy
This study looks at a new drug, Navtemadlin, for women with advanced endometrial cancer. It's for those who responded well to previous chemotherapy. The aim is to see if Navtemadlin can help keep the cancer from coming back for longer.
Advanced or Recurrent Endometrial CancerSlovenia