RecruitingNAINTERVENTIONAL

Development of Clinical and Biological Database

This project aims to build a comprehensive collection of information and biological samples (like blood or tissue) from adult patients diagnosed with digestive, gynaecological, breast cancer, or sarcoma who are about to start treatment. This resource, called a Clinical Biological Database (BCB), will help researchers understand cancer at a very detailed level, looking at everything from how molecules interact to how the whole body responds. By gathering this valuable data, scientists hope to discover new ways to prevent, diagnose, and treat various types of cancer more effectively. The study is particularly interested in understanding how cancers grow, spread, and become resistant to treatments, which could lead to new tests and therapies in the future. It's a key part of improving cancer care in the UK.

At a glance

Status

Recruiting

Phase

Sponsor

Institut du Cancer de Montpellier - Val d'Aurelle

Enrolment target

4,000

Start

27 Jul 2017

Estimated completion

01 Nov 2037

Digestive Cancer Gynecologic Cancer Breast Cancer Sarcoma

What is this study about?

This important project is all about creating a special database and collection of samples to help us understand cancer more deeply. Think of it as putting together a huge puzzle where each piece of information from patients helps scientists see the bigger picture. We're carefully gathering information and samples, such as blood and tissue, from adult patients who have certain types of cancer and are about to start their treatment. These cancers include digestive cancers (like stomach or bowel cancer), gynaecological cancers (like ovarian or womb cancer), breast cancer, and a rarer type called sarcoma.

The main goal is to create a resource that researchers can use to learn more about how cancer works. This includes understanding why cancer develops, how it spreads, and why some cancers stop responding to treatment. By having access to a wide range of samples and detailed patient information, scientists hope to find new warning signs, develop better ways to diagnose cancer earlier, and discover more effective treatments. Ultimately, this work is designed to improve the health and care of cancer patients.

This study is part of a national effort to bring research and patient care closer together. By making sure scientists have high-quality samples and reliable patient information, we can speed up discoveries in cancer research. This collaborative approach means that information can be shared carefully and securely between different research teams across the country, leading to faster progress in understanding and fighting cancer for everyone's benefit.

Key takeaways

This study collects vital information and samples to understand cancer better.
It helps develop new prevention, diagnosis, and treatment methods for various cancers.
You must be an adult with a specific cancer type and about to start treatment.
Participation involves providing extra blood samples during routine tests and using tissue from planned surgery.
There are no extra procedures or visits required beyond your standard care.
Your contribution helps future cancer patients, with minimal personal risk.

Who may be eligible?

To be able to take part in this study, you need to be at least 18 years old and have been diagnosed with an invasive or early-stage tumour. This diagnosis must be for one of the following types of cancer: digestive cancer (like in the food pipe, stomach, pancreas, or bowel), gynaecological cancer (like in the ovary or womb), breast cancer, or sarcoma. You must also not have received any treatment for your current cancer yet, and your treatment plan needs to include at least one surgery to remove the tumour.

Another important requirement is that you must be willing to provide extra blood samples and give your clear written permission to participate after understanding all the details of the study. Your follow-up care must also be manageable, meaning there's no reason why it would be difficult for you to keep your appointments.

There are also some reasons why you wouldn't be able to join. These include if you're not part of a social security scheme, if you're pregnant or breastfeeding, if you're under legal guardianship, or if you're in an emergency situation. People whose regular follow-up would be a problem due to personal circumstances (like family, social, or geographical reasons) would also not be able to participate.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Have you been diagnosed with digestive, gynaecological, breast cancer, or sarcoma?
Are you about to start your first treatment for this cancer, which includes surgery?
Are you willing to provide extra blood samples and a tissue sample from your planned surgery?
Can you give informed written consent to take part?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, it primarily involves allowing researchers to collect extra blood samples from you. These samples will be taken when you are already having blood tests as part of your standard care. Additionally, tissue samples from your tumour, which are collected during your planned surgery, will be used for research. You won't undergo any extra procedures solely for this study. The researchers will also collect information about your health, diagnosis, and treatment from your medical records. There are no additional visits required beyond your usual hospital appointments. The study aims to collect information and samples at different stages of your treatment to build a comprehensive picture, but this will be integrated with your routine care. The total duration of your participation will depend on how long researchers continue to collect information relevant to your cancer type and treatment, but you will not have any extra commitments once your initial samples are taken and information collected.

Potential risks and benefits

The potential benefits of taking part are not directly personal but contribute significantly to future medical knowledge, which could lead to better diagnostics and treatments for people with cancer in the future. There are minimal risks involved, as the blood samples are taken at the same time as your routine blood tests, and the tissue samples come from your planned surgery—meaning no extra invasive procedures. You have the right to withdraw from the study at any time, for any reason, without it affecting your standard medical care.

Locations (1)

Institut regional du Cancer - Val d Aurelle
Verified postcode
Montpellier, France· Recruiting

Common questions

What is a 'biological collection'?

It means gathering samples like blood or tissue from patients for research purposes. These samples help scientists understand diseases at a detailed level.

Will taking part affect my cancer treatment?

No, participating in this study will not change or affect your planned cancer treatment in any way. It works alongside your existing care.

Who will have access to my information and samples?

Only approved researchers involved in cancer studies will have access. Your personal details will be kept confidential and anonymised wherever possible to protect your privacy.

Do I have to pay to join this study?

No, there are no costs associated with taking part in this research study.

Can I leave the study if I change my mind?

Yes, you can withdraw from the study at any time without giving a reason, and it will not affect your medical care.

How to find out more

david azria

david.azria@icm.unicancer.fr +33467613102 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.