RecruitingPHASE3INTERVENTIONAL

The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III

This study, called Thoracic POISE, is for people in the UK having surgery for lung, stomach, or food pipe cancer. Doctors are looking into new ways to help patients feel better after their operation and reduce problems. They also want to explore if a mix of natural health interventions, like vitamin D drops, specific supplements, and advice on healthy eating and exercise, can help improve recovery and long-term health. The aim is to see if these combined approaches can make a real difference in how well patients recover, reduce the chances of cancer coming back, and improve their overall quality of life after surgery.

At a glance

Status

Recruiting

Phase

PHASE3

Sponsor

Ottawa Hospital Research Institute

Enrolment target

Start

04 Apr 2022

Estimated completion

01 Dec 2029

Lung Cancer Gastric Cancer Esophageal Cancer

What is this study about?

When people have surgery for cancers such as those in the lung, stomach, or food pipe, they often face significant challenges during their recovery. Many patients experience issues after their operation, and there's also a natural worry about the cancer returning later on. These concerns, along with the effects of treatments like chemotherapy, can really impact how someone feels and their overall quality of life.

This study, called Thoracic POISE, is trying a new approach. Instead of just looking at one treatment, it combines several different strategies, much like how people might use a variety of health methods in their daily lives. The aim is to see how a package of care, including specific supplements and advice on diet, exercise, and mental well-being, can work together with surgery to improve patient outcomes.

The main goal of this research is to make things better for patients having these operations. The study hopes to reduce the problems that can happen around the time of surgery, help people live longer and healthier lives after treatment, and improve their general well-being. It's also pioneering new ways to bring together traditional medical care with natural health approaches that might offer extra support.

Key takeaways

Aims to improve recovery and quality of life after cancer surgery.
Focuses on lung, stomach, and food pipe cancers.
Combines natural health approaches with standard treatment.
Includes advice on diet, exercise, and mental well-being.
Could help reduce problems after surgery and prevent cancer recurrence.

Who may be eligible?

To join this study, you must be an adult who is going to have surgery to completely remove lung, stomach, or food pipe cancer. This surgery must aim to fully get rid of the cancer. You also need to be at least 18 years old.

There are some reasons why you might not be able to join. For example, if you have certain types of cancer like small cell lung cancer or stomach cancers called GIST, you wouldn't be eligible. Also, if you've had cancer treatment within the last three years (unless it was for a very early bladder or skin cancer), you wouldn't be able to take part. This study is also not for pregnant or breastfeeding women. If you've been seeing a natural health practitioner recently, or if you're taking part in another medical study or using an experimental drug, you also wouldn't be able to join.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 or older?
Are you having surgery for lung, stomach, or food pipe cancer that aims to remove it completely?
Have you not had cancer treatment for other cancers (apart from very early skin or bladder cancer) in the last 3 years?
Are you not currently pregnant or breastfeeding?
Are you not taking part in another medical study or using an experimental drug?

Answer every question to see your result.

What does participation involve?

We cannot provide details on taking part in this specific study without more information. Generally, joining a study like this might involve regular visits to a clinic or hospital, providing blood samples, and filling out questionnaires about your health and how you're feeling. You would likely receive the study supplements (like vitamin D drops or other nutritional products) and follow specific recommendations for diet and exercise. Researchers would probably check your progress and health over a period of time, perhaps for several months or even years after your surgery. You would always be fully informed about what's involved before you agree to take part.

Potential risks and benefits

Participating in a study like this might offer potential benefits, such as receiving extra support and nutritional guidance that wouldn't normally be part of standard care. It could also help researchers learn more about how to improve care for future patients. However, there might also be potential risks, such as side effects from the supplements, though these would be carefully monitored. You would have the right to withdraw from the study at any time, for any reason, without affecting your usual medical care.

Locations (2)

The Ottawa Hospital
Verified postcode
Ottawa, Canada· Recruiting
Michael Garron Hospital
Verified postcode
Toronto, Canada· Recruiting

Common questions

What kind of cancers is this study looking at?

This study is for people having surgery for lung, stomach (gastric), or food pipe (oesophageal) cancer.

What are 'interventions' in this study?

Interventions are the different approaches being tested, like vitamin D drops, specific supplements, and advice on healthy eating and exercise.

What is the main goal of the study?

The main goal is to improve how patients recover from surgery, reduce problems, and enhance their overall quality of life after cancer treatment.

Will I still receive my usual cancer treatment?

Yes, this study aims to see if these extra interventions can help alongside your standard medical and surgical care.

Who is funding this research?

The study brief doesn't specify the funding body, but all clinical trials undergo ethical review to ensure patient safety and scientific rigour.

How to find out more

Anna Fazekas, MA, CCRP

afazekas@toh.ca 613-737-8899 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.