Alcohol injections as BPH treatment

Posted , 20 users are following.

This is from the Dailymail :

Hope for millions of men with enlarged prostates as scientists discover the gland can be shrunk with direct injections of alcohol

Injecting ethanol directly into the prostate could shrink it by more than a third

And it reduces how often men need to get up in the night to urinate

One expert said the pioneering treatment is 'excellent news'

'Ethanol injection can be an effective, non-surgical alternative in treatment of patients with [an enlarged prostate].'

The scientists tested the therapy on 60 middle-aged men by injecting nine shots of pure alcohol – ethanol – directly into their prostates through the rectum.

Their prostates were around 35 per cent smaller on average.

Doctors suggest this reduction is caused by the alcohol killing off unwanted cells, shrinking any swelling. 

And the men suffered from 48 per cent fewer symptoms, which can include difficulty urinating and needing the toilet frequently.

There were no severe side-effects of the jab, whereas some currently-used drugs can reduce men's sex drives.'

1 like, 59 replies

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  • Posted

    Good idea tim

    clinicaltrials <dot> gov/ct2/show/NCT00037141

    • Posted

      I looked it up. Trial was completed 2004, but no results were posted.

  • Posted

    Go to youtube and search Fexapotide Triflutate Filter your results to the last year. This drug has been going through trials for years. I don't know if this video is a marketing ploy or not. There seems to be pretty good results reported ealier this year ( 2018 ) The video I'm talking about is the second one that shows up with above search criteria. There are other injectables that are in trials also.

    • Posted

      Thanks unckle. I looked it up. Fexapotide Triflutate was not approved in Europe, citing lack of efficacy. From the way Nymox stock is acting, it probably will not be approved in the US neither. Too bad for us sufferers.

    • Posted

      I looked it up. It was not approved in Europe due to lack of efficacy. Many suspect it will not be approved in the US either.

    • Posted

      Hank

      Which trial did you look at.

      I got some of the information from a trail that was done December of 2017There was not that much information the only thing I could come up with that the man had a 35 % improvement.

      It was done at Venezuela at a Medical Center there. I sent them a e-mail have not heard anything .

      This I think would be great for a lot of men but I also feel it would put a lot of procedure out of business. But who know Time will tell

      Oh well let me go get more Brandy....Have a good night......Ken

  • Posted

    Unless some reputable medical journals are reporting scientific advances I would not be too concerned.

    • Posted

      Hesseiny works at some very prestigious English hospitals including Charing Cross.

  • Posted

    Hi Hank 53..........I have not been able to navigate this site, so, I am sorry that it has taken a long time to answer you. I have learned much in recent times and just wanna' tell you about a little discovery of mine in relation to your "self Cath" statement of perhaps one month ago.

    In my research I discovered that some men have their prostrate massaged by a doctor and this is done via the rectum. This is one treatment that I could not allow, so thinking through the plumbing of our prostrate area, I decided to use a small soft kiddies ball to perform a similar "rolling" pressure to the prostrate area. This is done by sitting on the ball and rolling it forward and back. Over the past month, I have saved myself on two separate occasions where I would have required a catheter insertion.

    All-in-all, my 75mm prostrate has been reduced in size by the use of Tamsulosin and Finasteride tablets for the past 120 days....plus a major change of diet. I stopped the use of all sugary foods, all acidic foods and all food additives, coffee and alcohol. I have only twice reverted to coffee and/or alcohol and paid the price.....but saved by my "prostrate massage ball" method. My next step is to go back for an ultrasound and other tests. To correct my urine acid level, I use small amounts of baking soda. I find it quite easy to maintain a Ph of 7.5 to 8.0. I dont really know very much about this and guess the amount of baking soda to match my food intake....and it seems to work. Hope that this info will help you. Cheers and happy New Year.

    • Posted

      Thanks for sharing your tips. I am glad you are doing well. Re the kiddies ball, how large is it? Would a tennis ball be good enough for your prostate message?

      Re urine pH, I think the best level is 7.0. Too high or too low raises bladder stones risk. Hank

  • Posted

    Here's an abstract of the article. Not supposed to post a link.

    Journal of EndourologyVol. 25, No. 3 Transurethral and Lower Tract Procedures

    Dr. El-Husseiny looks well-credentialed but you English chaps can tell me whether that is true:

    Primary medical qualifications

    MBBCh (Hons) MSc MRCS MD FEBU FRCS (Urol)

    Foreign languages

    ArabicGender

    Male

    Services

    UrologyHospitals

    Charing Cross HospitalSt Mary's Hospital

    Transurethral Ethanol Ablation of the Prostate for Symptomatic Benign Prostatic Hyperplasia: Long-Term Follow-Up

    Tamer El-Husseiny, Noor Buchholz

    Abstract

    Background and Purpose: Over the past decade, a variety of new minimally invasive therapies (MIT) have been developed for the treatment of patients with bladder outflow obstruction from benign prostatic hyperplasia (BPH). Transurethral ethanol ablation of the prostate (TEAP) has been introduced as a minimally invasive alternative treatment for patients with BPH. In this study, we present our experience and results of long-term follow-up of 54 months after treatment of symptomatic BPH with TEAP.

    Patients and Methods: Fifty-six men with symptomatic BPH were enrolled in our study; all patients were medically high-risk patients with multiple comorbidities. Procedures were performed under intravenous sedation combined with local urethral instillation of lidocaine jelly and a transrectal ultrasonography (TRUS)-guided periprostatic block. Dehydrated ethanol in a concentration of 95% to 98% was injected transurethrally by means of the Postaject Ethanol Injection System using a rigid cystoscope.

    Results: The following data were collected: International Prostate Symptom Score, prostate-specific antigen level, prostate volume using TRUS, maximum urine flow rate, and postvoid residual. There was sufficient response in 73% of our patients, while the remaining 23% showed an insufficient response and needed alternative treatment.

    Conclusion: TEAP is an effective minimally invasive treatment option for medically high-risk symptomatic patients with BPH that can be performed as an outpatient procedure under regional anesthesia. The procedure is easy, available, inexpensive, safe, and rapid. Further larger-scale, long-term multi-institutional trials are needed.

    • Posted

      Motto

      Thank you for finding this. Going to do more research on it

      Ken

    • Posted

      Hey Tim

      That may be a lot of fun.

      I was reading something today about that. You know they tells us to stay away for alcohol because it is no good for the prostate.

      I was reading a article this morning that having no more then 2 drinks a day can help the prostate. So who are you going to believe.

      I don't drink much now but if I want it I'm going to have it.

      I hope something comes out of this.........Ken

    • Posted

      Read the whole study. Looks interesting/promising. I found another article that said using injections for this has been done for 100 years. Also, the two doctors do not seem to be quacks.

    • Posted

      Metto

      Yes a few weeks ago I read something about that it was tried in 1938. But don't know why it never goes through. Will keep a eye on this. I think it will be good for many men that do not want to go through a surgery.

      Ken

    • Posted

      Thanks Motto. I've also read a trial results of transurethral injection from 2001-2005 yielding very good results. What puzzled me was why it did not go further and become more popular.

    • Posted

      Well, I'm cynical but I tend to think that here in the U.S. things that don't cost much don't tend to get adopted because doctors can't make much money doing them. What self-respecting Uro wants to do an injection for $500 when he can do a TURP for $15,000? Just a cycnical guess.

    • Posted

      Hey Tin and All Others

      Good morning. I just got a e-mail back from one of the doctors that was involved in some of the trails Professor Raj Persad for the Alcohol Injections . He does not know when it will be coming to the UK or US. For now it is only being done in Brazil.

      That is all I know for now.

      Have a good day........Ken

    • Posted

      Kenneth1955, I´m from Brazil, is it possible for you to ask Prof Raj Persad which doctor/medical hospital is doing these injections in Brazil? Actually we didn´t know nothing about here, even mainstream media didn´t talk anything about it.

      Thank you

    • Posted

      Irp1

      Good Afternoon

      I will check my e-mail. I sent it to the hospital I thought they were doing them in. I will let you know.

      Take care Ken

    • Posted

      My wife read something somewhere that they were getting rare but serious side effects.

    • Posted

      Good morning

      Sorry that you have not hear from me. Still trying to find out were. The doctor did not know where in Brazil. I just sent a e-mail to the reporter that did the article December 2017.

      I will let you know when I heard something...Ken

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