D mannose..Not Working.... and more..

I had something similar, felt like I had a UTI, I KNEW I had a UTI, tests negative, kept getting worse.......and then came joint pain.  Doctor tried Septra (bactrim) (knocked it back but returned as soon as I stopped), Macrobid (did nothing) and Cipro (knocked it back but when stopped, symptoms came right back). Saw a urologist, nephrologist, arthritis doctor, thought I was losing my mind.   When the symptoms got very painful, it started showing up in urine tests.  It was a Proteus mirabilis infection, that I believe I had for 1 1\2 years. Only certain antibiotics work and sometimes it is resistant to even those. Proteus mirabilis infections can be treated with broad-spectrum penicillins or cephalosporins except in severe cases. It is not susceptible to nitrofurantoin (Macrobid) or tetracycline and has experienced increasing drug resistance of ampicillin, trimethoprim (Septra/Bactrim), and ciprofloxin. They also believe it is a trigger for Rheumatoid (sp?) arthritis.....hence joint pain.

Just sharing my experience, it may help someone since I know how horrible this can be.

oh, and D-mannose does nothing to help a Proteus mirabilis UTI, unlike E-coli infections.

I am so happy to have found this thread! I have MS and have suffered from chronic, repeated UTI's for years! I have one now and we are waiting on the culture to tell us what antibiotic I should take. I am scheduled for an important MS treatment to start Dec. 14th which I can't start if I have an infection so I MUST get this cleared up. I have been to a urologist who hasn't done much to help me other than to determine I don't have any kidney damage yet. This is the first time I ever even heard about e.coli being the issue. No big surprise that no one has ever told this to me. I am going to order some D Mannose powder right away and try the recommended protocol. I just want to say thank you for all the info (and to think today is Thanksgiving. How perfect)

Hey, everyone. I found this site after trying to find info on d-mannose dosing. I think I have read everyone's reply. I am so sorry y'all suffer and are on antibiotics so much. I hope someone can help me, as most of you seem very informed.

I am 53, just went through menopause. Very healthy and active. I eat right, take daily vitamin d, c, eat coconut oil, etc etc. Never been sick. Don't go to doctors.

Well about 3 months ago I started feeling a pressure after urinating. Had no idea what it was. Never had uti before. Well it wouldn't go away. After doing kiegel exercises thinking I need to make everything stronger, I Google and uti kept coming up. Bought test strips. Everyone from then until now shows positive leukocytes negative nitrates. This is long, sorry.

I have started taking high carvecol oregano oil, goldenseal and oregon grape extract. I got dmannosse 2 days ago. I'm trying natural route because I don't want antibiotics.....

However, I did go to doctor this past tuesday, got tested... yes uti...she put me on Bactrim for 3 days...it didn't work. She said stay on it...I said no.

So here I am. The test strip is lighter pink...where it was purple, and a few times it has been clear.

I would welcome any suggestions. I will pray for those of you suffering. Thank yiu!

HI Nicole. There is a new "preventative" antibiotic that works well on preventing your UTIs. It's called methemine hippurate. It is a large pill (we use a pill cutter) and it tastes awful but if you take it twice a day morning and night (not used for a UTI, you use it everyday when you don't have a UTI) you will find you don't get them. How it works is it changes your urine to formaldehyde and bacteria can't live in it. However, it's imperative that you drink tons of water, 82 oz at least, or you will find you have burning in your bladder. Also you must not miss even one dose! Be very regimented about it. Ask your Dr and try it. Yes it's expensive though as well! Grrr! Let us know if it works. Try it for a month.

This may sound weird, I was at one time convinced I had a UTI (for a long time), but urine culture came back negative, a couple of times.  I did a 24 hr urine for oxalates (can google) and found I had hyperoxaluria (high oxalates), it felt exactly like a UTI and if you google you will see the symptoms are the same.  After a low oxalate diet, I felt sooo much better.  Particularly if you feel like you have a UTI and have joint pain this might be it, just sharing my experience in order to perhaps help others.

As regards to mersa it has been found in research that copper kills it on contact. Bacteria has a negative charge and copper a positive one, the prevailing theory is copper rips the bacteria apart. You can buy a copper zinc pill zinc kills even viruses. The two are taken together due to the problem of each dumping the other from your system. A real issue too much of either is bad but together they work nicely in killing bacteria.

Ive found a new family 😉. I'm so glad I'm not the only one that struggles with uti. Ugh even writing it makes me cringe. I've suffered from them since i was about 8. Im 26 now. What's helped me is lots and lots of water, showering everyday and when i feel one coming i soak in hot hot water

it helps, even for just a moment, but if you've had them as much as i have even that brief moment of relief is a blessing. I will start the d mannose, I've never even heard of it. And pray one day there is a permanent cure for all of us who suffer so much. It is one of the worst pains. My heart goes out to all of us. We are uti warriors 😉

Hi,

I suffered with the same for months and the dis just kept giving me antibiotics after antibiotics. I was so miserable. I got recommended to a health clinic and they said I had ecoli. They gave me vibrational pills( don't laugh) and vitamins and supplements. I also take 2 waterfall dmannose each night. Touch wood I've been fine since end of October. Best £200 I've ever spent. Went back for follow up last week and the ecoli has gone.

Hi Nicole

Just reading these comments. I have had recurrent UTIs and constant burning on urination despite negative dipstick and MSUs for over 5 years! I have had USS, uti dynamics and 2 cystoscopies. Recent cystoscopy showed redness of the bladder wall but biopsy showed no inflammation so it's not interstitial cystitis/ chronic cystitis.

If you haven't had cystoscopy this is what you need. I am due to have what is known as bladder instillation therapy. From reading some of the comments below I couldn't find it mentioned. I am from the UK so there may be some differences in protocol but the theory is it stops the bacteria latching onto the bladder wall. There is evidence of effectiveness in recurrent UTIs and non-inflamed chronic bladder inflammation too. This may also help you.

I am also a doctor so I do know about this too :p

Hope it helps

Mel