Mirtazapine withdrawal

Posted , 136 users are following.

Hey everyone,

I've been on Mirtazapine 30mg since Feb his year but I've had alot of problems with. Ear infections, burning mouth syndrome etc. so my Psychiatrist think's I should come of it. He told me to cut down to 15mg and only take them for a week and then just stop. So I finally stopped taking the 15mg on Mon night and I feel terrible.

It's not just my moods (my depression/anxiety had been great before coming off med), I physically feel really sick, been feeling extremely nauseated and last night couldn't sleep because I kept thinking I was going to throw up. Is this a normal reaction coming off mirtazapine?

Because my depression/anxiety had gotten alot better, we didn't feel the need to just take me off mirtazapine and put on on another drug because I thought I was cured. Plus, I don't want to take any more antidepressants at all really.

PLEASE, any help or advice you offer would be greatly appreciated because I'm really worried now and I don't want to have to go back to taking mirtazapine sad .

Will the withdrawal last long? How long will it take to fully get the tablets out of my system?

Please help,

thanks,

Star

7 likes, 878 replies

878 Replies

Prev Next
  • Posted

    I have now been totally of Mirt. for 47 days and doing really well. It is so good to feel like myself again rather than that disconect that I felt on the Mirt. Each decrease in dosage has been a long trip to withdrawal hell for me, but did eventually pass.

    The headache that will just not quit is finally being less persistant and I am having blocks of time when it is totally gone. I beleive from my previous reductions that it will eventually go. I beleive it is the central nervous system just crying out to be dampened as it was on the Mirt. so I amy trying to be very regualted with my sleep regeime to assist.

    On Mirt. I put on 20kg and am very happy to say that 5kg of that has come of which gives me encouragement that the rest will be in the realm of reality that I can get rid of it. Always helps to start feeling better about yourself and your appearence.

    I read on one of the previous posts about not feelong so alone with all of this stuff with the help of this site and I totally agree. The various posts from others who understand were the encouragement that kept me hanging on in there.

    I would very much recomend that you use it for support as I found it invaluable and insightful.

    Best of luck on all of your roads forward, Danae

    • Posted

      I put 44kgms on in 5 years while on mirt! That's 7 stone! 😁 lost a stone but it deffo comes off alot slower than putting it on! 

      Unfortunately I had to go back on different anti ds so the weights coming off even slower but they have alot of food restrictions so half the time I can't be bothered to eat, so not a happy bunny but making progress with help from a good pyschologist, hopefully the meds will be reduced in a few months, least I will know what to expect.

  • Posted

    After getting hypomania from paroxetine last year, ive been taking mirta since november last year. Initially 30mg but since im kinda anti meds i try to keep dosage as little as possible and went down to 15mg. In the first months it really worked well, finally i could sleep a night (after a couple of years worsening insomnia). but then i started to get more and more tired so i did a quick taper within a couple of days 2.5 months ago. since  then my insomnia is worse than ever, cant sleep at night and when i finally fall aslweep at 6am i sleep half of the day. when i wake up i feel more depressed than ever, no energy at all, no motivation to get out of bed. total decrease in appetite and crying all day. all i want is to disappear and to feel nothing at all. i lost a lot of weight (i tend to be skinny so the weight gain of mirta was welcome for me). This is already more than 2 months, when will this get better?
  • Posted

    Hi Pearldrop.

    I was on mirtazapine for 2years; 30mg.

    I quit almost 3 months ago, tapered of to 15 in one month and than nothing.

    The withdrawal is/was really heavy.

    First month no sleep, no apetite, anxiety, paranoia, heart pain, headache, muscle pain, nausea, fatigue, crying moods,... I could go on.

    It was really difficult go cope with, certainly at work. I did use xanax often to ease the suffering.

    I still do take xanax when needed now.

    I have the feeling it is getting better now, but very slowly.

    Had a couple of 'good' days last week; but yesterday and today are really bad.

    It will get better again i suppose.

    Hang in there and let me know how you are doing!

    • Posted

      Hi kerkstraat,

      went to sleep last night with a temazepam. slept from 12-3, then was awake from 3-7. slept again until 11:30 and for some miraculous reason I got out of bed immediately (instead of just lying like a zombie or crying until 14:00 or longer). So today I seem to do a bitt better than the past couple of weeks. I have some private issues as well (divorce) which do not really contribute to ease my feelings.

      Furthermore I still feel very weak physcally. Sometimes kind of dizzyness attacks (but not the extreme dizzyness that paroxetine withdrawal causes), restless legs, anxiety, internal restlessness, lack of appetite, dissociation and still deeply depressed.

    • Posted

      Hi Kerkstraat,

       I am in the same boot as you were.Would you mind telling me how it ended up after 3 months? I am looking forward reading you. Nico

  • Posted

    Today is a very bad day again. yesterday I thought i felt a bit better, today im back to where i came from: general anxiety, restlessness, huge insomnia, extreme exhaustion/fatigue/weakness. Not the relaxed kind if tiredness that I used to have just before I went to sleep at night, no this is a kind of tiredness that completely disables me. Not even in my worst depressive episode I had something like this. It already started during the couple of months that I took mirta but since I stopped 10 weeks ago it only got worse. Is this a result of the messed up neurotransmitters in my brain or is something else going on? Will it get better one day? Im out of hope sad
    • Posted

      Hi Pearldrop.

      Same here...

      The tiredness is unpredictable and messes you up.

      I try to take it like it comes.

      Not having my best days either.

      I ran out of hope several times, but you should hang on untill the next day where you feel a bit better.

      I am seeing a neurologist in september, maybe he will have some answers for me.

      volhouden! wink

    • Posted

      Hi Pearldrop,

      I am in the same boot as you were.

      Would you mind telling me how it ended up after 10 weeks?

      I am looking forward reading you.

      Nico

  • Posted

    Hi Friend

    I have been into mirtaz for the past 2 1/2 yrs now. Iam taking 7.5mg. & would like to withdraw from the tab. The doc says to continue till the end. Iam not sure, whom to contact.If u have any advice from any good doc. let me know. Iam in india. Thank u. I pray for ur welfare and hope u too taper off.

    • Posted

      Hi

      You can talk to me .i am from delhi india and also stucked with mirtaz

      we can talk to discuss more

  • Posted

    Hello All,  I'm on about day 5 now of weaning off of Remeron.  I had almost always considered this as being the wonder drug and have been on it for a number of years.  But now I'm entirely understanding that the way I've been feeling lately is due to the terrible withdrawl symptoms.  Over the last few days, it has taken me through a real rollercoaster ride.  Some of my symptoms of withdrawl are: Insomnia (can't sleep at all), sore throat (flu like symptoms), thick mucus in the throat / constantly clearing my throat, chronic ear infection, racing thoughts, extreme tiredness, gassy / bloated, lack of appetite (this is a big one for me as I can lose weight very fast), dry mouth, feelings of being disconnected, confusion, racing thoughts (ie...can't turn off the television in my mind, especially when trying to sleep), huge mood swings, convulsions, night tremors.  There's so many really that it becomes almost difficult to define.......it just feels like crap.

    I've been on a consordium of medications that started for me about 20 years ago.  There have been so many that caused terrible side effects, I can't even begin to describe how terrible some of them were, but remeron seemed like "The one" because it caused weight gain for me and made me tired.  Now I'm at the point where I'm consciously saying that I need off of them.....for good.  I'm also very luck that I have a wife that is very understanding and  supportive.....definitely an important part for my recovery.

    What has worked so far: Well, the first few days were pretty rough, but I think one key element was to try to make things as comfortable as possible.  I have been playing on low volume very relaxing spa music.  It seems to take some of the edge off.  Also avoid things that are over stimulating (news events, high drama / violent tv programs).  I am also re-starting a CBT program to start retraining my mind to  provide positive inputs. A good trustworthy therapist is probably one of the best things I can do right now to move forward to ovecome this disease.  She is planning to assist with a relatively newer type therapy EMDR Eye Movement Desensitization and Reprogramming.  Along with this will be similar types of hypnotherapy.  I am looking forward to some day being "Brain drug" free.  I realize I'm only 5 days in, but I have the rest of my life to look forward to.

    • Posted

      Hi ryan99010, I was so interested to read of your experiences of the withdrawl symptoms. Yours is the first account I've read that includes the 'thick mucus in the throat/constantly clearing my throat'. I have been having the same problem and am due to see an ENT specialist next week as I hadn't connected these symptoms with the withdrawl from  mirtazepine. I'm also struggling with insomnia. I hope your symptoms have improved since you last posted and you're right, you HAVE got the rest of your life to look forward to smile
  • Posted

    Has anyone used periactin to help with the symptoms of remeron withdrawl.  I know that the effects of going off of remeron are appetite loss and throat tightness / scratchiness.  My biggest worry is weight loss as I'm going through the withdrawl steps.  Anyone have any insight on whether periactin has it's own withdrawl symptoms.
  • Posted

    I'm so thankful for this forum and the people who post. I am currently on 7.5 down from 15. I have tried the every other day approach and actually it's not so bad. I'm on day ten and yesterday and today I noticed tremendous fatigue ....not sleepy but exhausted and it so hard to push myself through my day and muscle aches in my hips. Some gastro disorders but nothing much no bad dream or panic. I mean if this is the worst I can deal with it. But I have a feeling this isn't the worst. No matter I will succeed in getting off this medication. I alerted my family that I'm in the process and they know, but don't understand completely...big deal neither does my doctor.

    when I quit paxil it was difficult I'd say but the withdrawl was almost immediate like day two, and each day it seemed to get better and better, about two months worth with each day brighter. The problem with the mirt is that it doesn't stat right away, might take a week or longer( I've read for some reason women metabolize it differently and it takes longer to feel the withdrawal.)

    so, I might get down to crumbs with my slow taper and still get hit pretty bad in a week or even two....I know this time I won't hop back on. I can't , it causing to much pain as it is.

    its a great drug for anxiety for me and for sleep, but people should be warned that it's very difficult to come off from. 

    i mean for me because I'm older, if it didn't cause muscle pains, I resign myself to be on it for life. Like an anti depressant it also poops out. I've been on it for several years. Soon it loses it's abilities. But it does not lose the inability to get rid of it.

    im trying to stay positive. I know for me the gastro will be the worst so I'm prepared.

    last time I got off I lost 12 pounds in 21 days. So don't worry about the weight gain, it will all come off plus some. ( I have not regained any weight since then either) 

    so I'm thinking every third night starting this Monday. If it's to much I'm back to every other night.

    I wish good luck good health...find a support system. Tell those you trust. Maybe they can help lighten the load

    peace

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.